Needles is a city in San Bernardino County, California, in the Mojave Desert region of Southern California. Situated on the western banks of the Colorado River, Needles is located near the Californian border with Arizona and Nevada. The city is accessible via Interstate 40 and U.S. Route 95. The population was 4,959 at the 2020 census, up from 4,844 at the 2010 census.