Regina Pizzeria, also known as Pizzeria Regina, and originally called Regina Pizza, is a regional pizza chain in New England. The company was founded in 1926 by Luigi D'Auria in Boston's North End neighborhood. It has been run by the Polcari family since 1956. The chain is a part of Boston Restaurant Associates and is headquartered in Woburn, Massachusetts. Regina Pizzeria is one of the most well-known pizza restaurants in Boston, and has a rivalry with the also-well-known Santarpio's Pizza.