Rodolfo Pio da Carpi (22 February 1500 – 2 May 1564) was an Italian Cardinal, humanist and patron of the arts. The nephew of a diplomat, he himself became a diplomat by the age of thirty, and came to know both Emperor Charles V and King Francis of France, and he negotiated with both on behalf of the pope. His uncle, Alberto Pio da Carpi, had been educated by Pico della Mirandola, and had become a noted humanist scholar. These associations formed Rodolfo's background and education. He formed a notable library and participated in the humanist studies of 16th-century Rome; he also served on the Roman Inquisition. He helped to establish the Inquisition at Milan.