Ruthwell is a village and parish on the Solway Firth between Dumfries and Annan in Dumfries and Galloway, Scotland. Thomas Randolph, Earl of Moray, gave Ruthwell to his nephew, Sir William Murray, confirmed to Sir John Murray, of Cockpool, in 1509 by King James VI. He was later given the title Earl of Annandale: their landownings in Ruthwell passed by inheritance to Lord Stormont in 1658, and after 1792 to the Earls of Mansfield. The village was once served by Ruthwell railway station.