Samuel George (1795 – September 24, 1873) was an influential Onondaga Indian chief, holding the title Hononwirehdonh, or "Great Wolf" for twenty-three years. He served in the War of 1812 and was a renowned healer and orator among Indians and whites. Modern-day historian Laurence Hauptman describes George as an Iroquoian conservative who supported traditional Iroquoian ceremonies, language, and land rights, but also allowed missionaries and schools on the reservation.