Samuel Shepheard (1677–1748), of Exning, Suffolk, near Newmarket, Cambridgeshire, was an English Tory politician who sat in the English House of Commons in 1701 and in the British House of Commons almost continually for forty years from 1708 to 1748. Shepheard was the second surviving son of Samuel Shepheard and his wife Mary Chamberlayne, daughter of Edward Chamberlayne of Princethorpe, Warwickshire. He was a director of the East India Company from 1717 to 1720. When his unmarried elder brother Francis died in 1739, he inherited his estate, including .