San Angelo (/sæn ˈændʒəloʊ/ SAN AN-jə-loh) is a city in and the county seat of Tom Green County, Texas, United States. Its location is in the Concho Valley, a region of West Texas between the Permian Basin to the northwest, Chihuahuan Desert to the southwest, Osage Plains to the northeast, and Central Texas to the southeast. According to a 2019 Census estimate, San Angelo had a total population of 101,004. It is the principal city and center of the San Angelo metropolitan area, which had a population of 118,182.