Santa Ana is one of the 28 barangays of Taguig, Metro Manila, Philippines. It is located in the north eastern part of the city and is bounded by the barangays of Calzada and Palingon on the north, the Bambang and Wawa on the south and the barangays of Tuktukan and Ususan on the west, and the Laguna de Bay on the southeast. It was the old municipal center of Taguig from its establishment in 1587 during the Spanish colonization of the Philippines. Saint Anne is the patroness of the barangay.