Santa Cruz de Coya was a city established by the governor of Chile Martín García Oñez de Loyola on the site of the fort of Santa Cruz de Oñez, in 1595. It was named for his wife Beatriz Clara Coya, a member of the royal Incan house. The Mapuche called the city Millacoya, meaning gold princess from the mapudungun milla, gold and the quechua coya, princess.