Scientific skepticism or rational skepticism (also spelled scepticism), sometimes referred to as skeptical inquiry, is a position in which one questions the veracity of claims lacking empirical evidence. In practice, the term most commonly references the examination of claims and theories that appear to be beyond mainstream science, rather than the routine discussions and challenges among scientists. Scientific skepticism differs from philosophical skepticism, which questions humans' ability to claim any knowledge about the nature of the world and how they perceive it, and the similar but distinct methodological skepticism, which is a systematic process of being skeptical about (or doubting) the truth of one's beliefs.