The Sebec-Piscataquis River Confluence Prehistoric Archeological District encompasses a collection of important prehistoric archaeological sites in Milo, Maine. Located near the mouth of the Sebec River where it meets the Piscataquis River, these sites include several deeply stratified sites covering 5,000 years of history dating back to 8,300 BCE. The area was listed on the National Register of Historic Places in 1986.