Soyuz MS-22 is a Russian Soyuz spaceflight to the International Space Station with a crew of three launched from Baikonur Cosmodrome on 21 September 2022. The launch was previously planned for 13 September 2022, but in the provisional flight manifest prepared by Roscosmos by the end of Summer 2020, the launch of Soyuz MS-22 was delayed to 21 September 2022, for a mission length of 188 days. The mission was planned before the 2022 Russian invasion of Ukraine, however, continued international collaboration around the ISS has been thrown into doubt by the ongoing event and related sanctions on Russia.