The Susquehanna River (/ˌsʌskwəˈhænə/; Lenape: Siskëwahane) is a major river located in the Mid-Atlantic region of the United States, overlapping between the lower Northeast and the Upland South. At 444 miles (715 km) long, it is the longest river on the East Coast of the United States. By watershed area, it is the 16th-largest river in the United States, and also the longest river in the early 21st-century continental United States without commercial boat traffic.