The Théâtre du Palais-Royal (or Grande Salle du Palais-Royal) on the rue Saint-Honoré in Paris was a theatre in the east wing of the Palais-Royal, which opened on 14 January 1641 with a performance of Jean Desmarets' tragicomedy Mirame. The theatre was used by the troupe of Molière from 1660 to 1673 and as an opera house by the Académie Royale de Musique from 1673 to 1763, when it was destroyed by fire. It was rebuilt and reopened in 1770, but again was destroyed by fire in 1781 and not rebuilt.