The Thirty Years' War was one of the longest and most destructive conflicts in European history, lasting from 1618 to 1648. Fought primarily in Central Europe, an estimated 4.5 to 8 million soldiers and civilians died as a result of battle, famine, and disease, while some areas of what is now modern Germany experienced population declines of over 50%. Related conflicts include the Eighty Years' War, the War of the Mantuan Succession, the Franco-Spanish War, and the Portuguese Restoration War.