Col. Thomas Lee (c. 1690–November 14, 1750) was a planter and politician in colonial Virginia. He was a member of the Lee family, a political dynasty which included many figures from the colonial era until the late twentieth century. Lee became involved in politics in 1710 and became the resident manager of the Northern Neck Proprietary for Lady Catherine Fairfax. After his father died, Lee inherited land in Northumberland and Charles County. Lee later acquired vast holdings in what are now Arlington, Fairfax, Fauquier, Prince William, and Loudoun Counties. These properties were developed as tobacco plantations.