Tirli is a village in Tuscany, central Italy, administratively a frazione of the comune of Castiglione della Pescaia, province of Grosseto. At the time of the 2001 census its population amounted to 284. Tirli is about 28 km from Grosseto and 18 km from Castiglione della Pescaia, and it is situated on a hill next to the top of Poggio Ballone.