USS Spruance (DD-963) was the lead ship of the United States Navy's Spruance class of destroyers and was named after Admiral Raymond A. Spruance. Spruance was built by the Ingalls Shipbuilding Division of Litton Industries at Pascagoula, Mississippi, and launched by Mrs. Raymond A. Spruance. Spruance served in the U.S. Atlantic Fleet, assigned to Destroyer Squadron 24 and operating out of Naval Station Mayport, Florida. Spruance was decommissioned on 23 March 2005 and then was sunk as a target on 8 December 2006.