Vyazemsky District (Russian: Вя́земский райо́н) is an administrative and municipal district (raion), one of the seventeen in Khabarovsk Krai, Russia. It is located in the southwest of the krai. The area of the district is 4,318 square kilometers (1,667 sq mi). Its administrative center is the town of Vyazemsky. As of the 2010 Census, the total population of the district was 22,974, with the population of the administrative center accounting for 63.4% of that number.