William Custis (1633 – 1698) was a North American Colonial British merchant, planter and politician, and one of the founders of the Custis Family of Virginia, one of the First Families of Virginia. The Netherlands-born younger brother of merchant was naturalized with his brother in 1658. Their father, Henry Custis, had emigrated to Rotterdam in the Netherlands from Gloucester County in England to escape the English Civil Wars, and operated a tavern catering to fellow emigrants, as well as engaged in commerce. His elder sister Ann married , the son of Sir George Yeardley, who twice served as Governor of the Virginia Colony, where Sir George died in 1627. In 1649 or 1650, John Custis II traveled to Jamestown with his sister and her husband, and William Custis also emigrated to the colony.