William Neal Deramus Jr. (March 25, 1888 – December 2, 1965) was an American railroad executive. He served as the longest running president (20 years) of the Kansas City Southern Railway (KCS) from 1941 to 1961. Deramus led the Kansas City Southern Railway through the Great Depression by encouraging industry to locate on the Gulf Coast in Louisiana and Texas. He helped the railway to avoid bankruptcy in the 1930s and refinanced $67 million in bonded debt that fell due in the late 1940s.