Yerseke (Dutch: [ˈirsəkə], Zeelandic: [ˈisə]) is a village situated on the southern shore of the Oosterschelde (Eastern Scheldt) estuary in the Dutch province of Zeeland. A separate municipality until 1970, it today forms part of the municipality of Reimerswaal. As of 2010 Yerseke had a recorded population of 6,695 inhabitants, living in 2,680 households.