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Statements

Subject Item
dbr:Lidoflazine
rdf:type
yago:Analgesic102707683 yago:Drug103247620 yago:Vermifuge104528630 owl:Thing yago:Piperazine103946814 dbo:ChemicalSubstance yago:WikicatMolecularFormulas yago:Abstraction100002137 n17:ChemicalObject yago:Statement106722453 yago:WikicatAcetanilides wikidata:Q8386 dbo:Drug yago:Matter100020827 yago:CausalAgent100007347 yago:MolecularFormula106817173 umbel-rc:DrugProduct yago:Communication100033020 yago:WikicatPiperazines yago:Formula106816935 yago:Acetanilide102674912 yago:Message106598915 yago:Substance100020090 yago:PhysicalEntity100001930 yago:Agent114778436 yago:Medicine103740161
rdfs:label
Lidoflazina Lidoflazyna Lidoflazine
rdfs:comment
Lidoflazine is a piperazine calcium channel blocker. It is a coronary vasodilator with some antiarrhythmic action. Lidoflazine was discovered at Janssen Pharmaceutica in 1964. Lidoflazyna (łac. lidoflazinum) – wielofunkcyjny organiczny związek chemiczny, będący pochodną piperazyny, lek w przeszłości stosowany w leczeniu choroby niedokrwiennej serca, obecnie wycofany z rynku z powodu wpływu na wydłużenie odstępu QT, o działaniu blokującym kanały wapniowe oraz kanały potasowe hERG. Lidoflazina, nella fase sperimentale conosciuto anche con la sigla R 7904, è un calcio-antagonista dotato di azione vasodilatatrice coronarica, che è stato a lungo utilizzato per il trattamento dell'angina pectoris.
foaf:depiction
n15:lidoflazine.png n15:Lidoflazin_synthesis.svg
dct:subject
dbc:Calcium_channel_blockers dbc:Fluoroarenes dbc:Belgian_inventions dbc:Acetanilides dbc:HERG_blocker dbc:Janssen_Pharmaceutica dbc:Piperazines
dbo:wikiPageID
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dbo:wikiPageRevisionID
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dbo:wikiPageWikiLink
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dbp:solubility
Almost insoluble in water; Very soluble in chloroform;
dbp:wikiPageUsesTemplate
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dbo:thumbnail
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dbp:atcSuffix
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dbp:atcPrefix
8.0
dbp:c
30
dbp:casNumber
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dbp:chemspiderid
3789
dbp:f
2
dbp:h
35
dbp:iupacName
2
dbp:kegg
D04733
dbp:meltingHigh
161
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159
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3
dbp:o
1
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CC1=CNCCN2CCNCCCCC4=CC=CF
dbp:stdinchi
1
dbp:stdinchikey
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dbp:unii
J4ZHN3HBTE
dbp:verifiedfields
changed
dbp:verifiedrevid
447611733
dbp:watchedfields
changed
dbo:abstract
Lidoflazyna (łac. lidoflazinum) – wielofunkcyjny organiczny związek chemiczny, będący pochodną piperazyny, lek w przeszłości stosowany w leczeniu choroby niedokrwiennej serca, obecnie wycofany z rynku z powodu wpływu na wydłużenie odstępu QT, o działaniu blokującym kanały wapniowe oraz kanały potasowe hERG. Lidoflazine is a piperazine calcium channel blocker. It is a coronary vasodilator with some antiarrhythmic action. Lidoflazine was discovered at Janssen Pharmaceutica in 1964. Lidoflazina, nella fase sperimentale conosciuto anche con la sigla R 7904, è un calcio-antagonista dotato di azione vasodilatatrice coronarica, che è stato a lungo utilizzato per il trattamento dell'angina pectoris.
gold:hypernym
dbr:Blocker
prov:wasDerivedFrom
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dbo:pubchem
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foaf:isPrimaryTopicOf
wikipedia-en:Lidoflazine