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Statements

Subject Item
dbr:Platinosis
rdf:type
dbo:Disease yago:Condition113920835 yago:PhysicalCondition114034177 yago:Disorder114052403 yago:State100024720 yago:Abstraction100002137 yago:Attribute100024264 yago:WikicatOccupationalDisorders owl:Thing wikidata:Q12136
rdfs:label
Platinosis
rdfs:comment
Platinosis is an allergy-like reaction to exposure to soluble salts of platinum. The symptoms of platinosis may include asthma, dermatitis, dyspnea, conjunctival vasodilatation, and rhinopharyngitis. The symptoms are progressive, sometimes taking months to years to appear. Platinosis is usually associated with workers in industries related to platinum production.The effects are permanent. Halogeno-platinum compounds are among the most potent respiratory and skin sensitisers known, therefore it is vital that exposure via the skin and by breathing contaminated air is carefully controlled.
dct:subject
dbc:Allergology dbc:Toxic_effects_of_metals dbc:Platinum dbc:Occupational_diseases
dbo:wikiPageID
2585714
dbo:wikiPageRevisionID
1090045146
dbo:wikiPageWikiLink
dbr:Conjunctiva dbr:Dermatitis dbc:Toxic_effects_of_metals dbr:Allergy dbr:Asthma dbr:Platinum dbr:Hexachloroplatinic_acid dbc:Allergology dbc:Platinum dbr:Platinum_nitrate dbr:Ammonium_hexachloroplatinate dbr:Ammonium_tetrachloroplatinate dbr:Vasodilator dbr:Heavy_metal_poisoning dbr:Cis-platin dbr:Pharyngitis dbr:Dyspnea dbc:Occupational_diseases dbr:Salt_(chemistry)
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dbo:abstract
Platinosis is an allergy-like reaction to exposure to soluble salts of platinum. The symptoms of platinosis may include asthma, dermatitis, dyspnea, conjunctival vasodilatation, and rhinopharyngitis. The symptoms are progressive, sometimes taking months to years to appear. Platinosis is usually associated with workers in industries related to platinum production.The effects are permanent. Halogeno-platinum compounds are among the most potent respiratory and skin sensitisers known, therefore it is vital that exposure via the skin and by breathing contaminated air is carefully controlled. In practice, the compounds mainly responsible for platinum sensitisation are typically the soluble, ionic, platinum-chloro compounds such as ammonium hexachloroplatinate and , and hexachloroplatinic acid. Other ionic halogeno compounds are also sensitisers, the order of allergenicity being Cl > Br > I. Neutral compounds such as cis-platin and ammine and nitro complexes such as [Pt(NH3)4]Cl2, K2[Pt(NO2)4] and are not considered to be allergenic; neither is the metal.
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dbr:Reaction
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