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Statements

Subject Item
dbr:4-Fluoroestradiol
rdf:type
wikidata:Q8386 owl:Thing dbo:Drug dbo:ChemicalSubstance n16:ChemicalObject
rdfs:label
4-Fluoroestradiol
rdfs:comment
4-Fluoroestradiol (4-FE2) is a synthetic estrogen and a derivative of estradiol which was never marketed. It is specifically the 4-fluoro analogue of estradiol. 4-Fluoroestradiol has 180 ± 43% of the affinity of estradiol for the estrogen receptor of rat uterine cytosol and shows potent uterotrophic activity similar to that of estradiol in mice and rats. It has been labeled with fluorine-18 (18F) for potential use in medical imaging.
owl:differentFrom
dbr:16α-Fluoroestradiol
foaf:depiction
n10:4-Fluoroestradiol.svg
dct:subject
dbc:Estranes dbc:Abandoned_drugs dbc:Synthetic_estrogens dbc:Phenols dbc:Secondary_alcohols dbc:Fluoroarenes
dbo:wikiPageID
64332510
dbo:wikiPageRevisionID
1120783435
dbo:wikiPageWikiLink
dbr:Chemical_derivative dbr:Structural_analog dbr:Cytosol dbr:Uterine dbc:Fluoroarenes dbr:Fluoro dbc:Estranes dbr:Estrogen_receptor dbr:Medical_imaging dbr:Potency_(pharmacology) dbc:Abandoned_drugs dbr:Estrogen_(medication) dbr:Fluorine-18 dbc:Phenols dbc:Secondary_alcohols dbr:Uterotrophic dbr:Estradiol_(medication) dbc:Synthetic_estrogens dbr:Affinity_(pharmacology) dbr:Radiolabel dbr:16α-Fluoroestradiol dbr:Synthetic_compound
owl:sameAs
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dbt:Distinguish dbt:Drugbox dbt:Short_description dbt:Estrogen_receptor_modulators dbt:Reflist dbt:Genito-urinary-drug-stub dbt:Selected_biological_properties_of_endogenous_estrogens_in_rats dbt:Steroid-stub
dbo:thumbnail
n10:4-Fluoroestradiol.svg?width=300
dbp:c
18
dbp:casNumber
1881
dbp:chembl
1627337
dbp:chemspiderid
8261159
dbp:class
dbr:Estrogen_(medication)
dbp:f
1
dbp:h
23
dbp:iupacName
-4
dbp:o
2
dbp:pubchem
10085622
dbp:smiles
C[C@]12CC[C@H]3[C@H]CCC4=C3C=CCO
dbp:stdinchi
1
dbp:stdinchikey
QZFXMXJXAUMHQR-ZHIYBZGJSA-N
dbp:synonyms
4
dbo:abstract
4-Fluoroestradiol (4-FE2) is a synthetic estrogen and a derivative of estradiol which was never marketed. It is specifically the 4-fluoro analogue of estradiol. 4-Fluoroestradiol has 180 ± 43% of the affinity of estradiol for the estrogen receptor of rat uterine cytosol and shows potent uterotrophic activity similar to that of estradiol in mice and rats. It has been labeled with fluorine-18 (18F) for potential use in medical imaging.
prov:wasDerivedFrom
wikipedia-en:4-Fluoroestradiol?oldid=1120783435&ns=0
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4439
dbo:casNumber
1881-37-4
dbo:chEMBL
1627337
dbo:pubchem
10085622
dbo:class
dbr:Estrogen_(medication)
foaf:isPrimaryTopicOf
wikipedia-en:4-Fluoroestradiol