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Statements

Subject Item
dbr:CFP-10
rdf:type
yago:Part113809207 yago:Thing100002452 umbel-rc:ProteinMolecule yago:Abstraction100002137 yago:Molecule114682133 yago:Macromolecule114944888 yago:Compound114818238 yago:PhysicalEntity100001930 yago:Matter100020827 yago:Substance100019613 yago:OrganicCompound114727670 yago:Material114580897 yago:Relation100031921 dbo:Protein yago:Chemical114806838 yago:Unit109465459 yago:Protein114728724
rdfs:label
CFP-10
rdfs:comment
CFP-10 within bacterial proteins (also known as ESAT-6-like protein esxB or secreted antigenic protein MTSA-10 or 10 kDa culture filtrate antigen CFP-10) is a protein that is encoded by the esxB gene. CFP-10 is a 10 kDa secreted antigen from Mycobacterium tuberculosis. It forms a 1:1 heterodimeric complex with ESAT-6. Both genes are expressed from the RD1 region of the bacterial genome and play a key role in the virulence of the infection.
dbp:name
10
foaf:depiction
n13:CFP-10.jpg
dct:subject
dbc:Tuberculosis dbc:Bacterial_proteins
dbo:wikiPageID
11561317
dbo:wikiPageRevisionID
1105807277
dbo:wikiPageWikiLink
dbr:Bacterial_proteins dbr:Protein dbr:Amino-acid dbr:Genome dbr:Mycobacterium_tuberculosis dbc:Tuberculosis dbr:Gene dbc:Bacterial_proteins dbr:ESAT-6 dbr:QuantiFERON dbr:Antigen dbr:Macrophage dbr:Heterodimer dbr:Monocyte dbr:Virulence
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dbp:wikiPageUsesTemplate
dbt:Refend dbt:Reflist dbt:Cite_journal dbt:Cn dbt:Refbegin dbt:Infobox_nonhuman_protein
dbo:thumbnail
n13:CFP-10.jpg?width=300
dbp:caption
Structure of the CFP10-ESAT6 complex from M. tuberculosis.
dbp:organism
Mycobacterium tuberculosis
dbp:symbol
esxB
dbp:taxid
83332
dbp:uniprot
P0A566
dbo:abstract
CFP-10 within bacterial proteins (also known as ESAT-6-like protein esxB or secreted antigenic protein MTSA-10 or 10 kDa culture filtrate antigen CFP-10) is a protein that is encoded by the esxB gene. CFP-10 is a 10 kDa secreted antigen from Mycobacterium tuberculosis. It forms a 1:1 heterodimeric complex with ESAT-6. Both genes are expressed from the RD1 region of the bacterial genome and play a key role in the virulence of the infection.
dbp:chromosome
genome
dbp:entrezchromosome
NC_000962.2
dbp:entrezgene
886194
dbp:genlocEnd
4352620
dbp:genlocStart
4352228
dbp:pdb
3
dbp:refseqprotein
NP_218391
gold:hypernym
dbr:Protein
prov:wasDerivedFrom
wikipedia-en:CFP-10?oldid=1105807277&ns=0
dbo:wikiPageLength
4955
foaf:isPrimaryTopicOf
wikipedia-en:CFP-10