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Statements

Subject Item
dbr:Death_Domain_database
rdf:type
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rdfs:label
Death Domain database
rdfs:comment
The Death Domain database is a secondary database of protein-protein interactions (PPI) of the death domain superfamily. Members of this superfamily are key players in apoptosis, inflammation, necrosis, and immune cell signaling pathways. Negative death domain superfamily-mediated signaling events result in various human diseases which include, cancers, neurodegenerative diseases, and immunological disorders. Creating death domain databases are of particular interest to researchers in the biomedical field as it enables a further understanding of the molecular mechanisms involved in death domain interactions while also providing easy access to tools such as an interaction map that illustrates the protein-protein interaction network and information. There is currently only one database that
foaf:homepage
n16:www.deathdomain.org
dc:description
protein-protein interaction database for theDeath Domainsuperfamily.
dcterms:subject
dbc:Biological_databases dbc:Protein_domains
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owl:sameAs
n13:4j3RY freebase:m.0j28bgy yago-res:Death_Domain_database wikidata:Q5247117
dbp:wikiPageUsesTemplate
dbt:Orphan dbt:Third-party dbt:Infobox_biodatabase dbt:Multiple_issues dbt:Manual dbt:Reflist
dbp:author
Dongseop Kwon
dbp:description
protein-protein interaction database for the Death Domain superfamily.
dbp:released
2011
dbp:title
Death Domain Database
dbp:url
n16:www.deathdomain.org
dbo:abstract
The Death Domain database is a secondary database of protein-protein interactions (PPI) of the death domain superfamily. Members of this superfamily are key players in apoptosis, inflammation, necrosis, and immune cell signaling pathways. Negative death domain superfamily-mediated signaling events result in various human diseases which include, cancers, neurodegenerative diseases, and immunological disorders. Creating death domain databases are of particular interest to researchers in the biomedical field as it enables a further understanding of the molecular mechanisms involved in death domain interactions while also providing easy access to tools such as an interaction map that illustrates the protein-protein interaction network and information. There is currently only one database that exclusively looks at death domains but there are other databases and resources that have information on this superfamily. According to PubMed, this database has been cited by seven peer-reviewed articles to date because of its extensive and specific information on the death domains and their PPI summaries.
dbp:pmid
Kwon & al.
prov:wasDerivedFrom
wikipedia-en:Death_Domain_database?oldid=1047556332&ns=0
dbo:wikiPageLength
20652
dbo:title
Death Domain Database
foaf:isPrimaryTopicOf
wikipedia-en:Death_Domain_database