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Statements

Subject Item
dbr:Dystrophic_calcification
rdf:type
yago:PhysicalCondition114034177 yago:Abstraction100002137 dbo:Disease yago:Condition113920835 yago:Attribute100024264 yago:Disorder114052403 yago:WikicatMetabolicDisorders yago:MetabolicDisorder114084502 yago:State100024720
rdfs:label
تكلس ضموري (أنسجة) Calcificazione distrofica Dystrophic calcification
rdfs:comment
Dystrophic calcification (DC) is the calcification occurring in degenerated or necrotic tissue, as in hyalinized scars, degenerated foci in leiomyomas, and caseous nodules. This occurs as a reaction to tissue damage, including as a consequence of medical device implantation. Dystrophic calcification can occur even if the amount of calcium in the blood is not elevated (a systemic mineral imbalance would elevate calcium levels in the blood and all tissues) and cause metastatic calcification. Basophilic calcium salt deposits aggregate, first in the mitochondria, then progressively throughout the cell. These calcifications are an indication of previous microscopic cell injury, occurring in areas of cell necrosis when activated phosphatases bind calcium ions to phospholipids in the membrane. La calcificazione distrofica in campo medico, è il processo patologico di deposito del calcio in tessuti necrotici o in via di degenerazione. Questi più frequentemente sono valvole cardiache, cicatrici e vasi sanguigni aterosclerotici. A differenza della calcificazione metastatica qui non si mostrano ipercalcemia, o alterazioni del metabolismo del calcio. التكلس الضمور ( DC ) هو التكلس الذي يحدث في الأنسجة المتدهورة أو النخرية، كما هو الحال في الندوب المتحللة، والبؤر المتدهورة في الورم العضلي الأملس، والعقيدات الجبنية. يحدث هذا كرد فعل لتلف الأنسجة، بما في ذلك نتيجة زرع جهاز طبي.
foaf:depiction
n12:Amyloidosis,_dystrophic_calcification,_H&E.jpg
dcterms:subject
dbc:Histopathology
dbo:wikiPageID
1061554
dbo:wikiPageRevisionID
1062816036
dbo:wikiPageWikiLink
dbr:Haematoma dbr:Thrombus dbr:Calcification dbr:Calcinosis dbr:Calcinosis_cutis dbr:Toxoplasmosis dbc:Histopathology dbr:Mitochondria dbr:Infarct dbr:Fat_necrosis n13:Amyloidosis,_dystrophic_calcification,_H&E.jpg dbr:Schistosoma dbr:Monckeberg's_arteriosclerosis dbr:Angioid_streaks dbr:Hyalin dbr:Caseous_necrosis dbr:Atheroma dbr:Basophilic dbr:Phlebolith dbr:Phosphatase dbr:Cyst dbr:Rubella n13:Cardiovascular_calcification_-_Sergio_Bertazzo.tif dbr:Pseudoxanthoma_elasticum dbr:Hyaline dbr:Aorta dbr:Liquefactive_necrosis dbr:Metastatic_calcification dbr:Leiomyoma dbr:Bruch's_membrane dbr:Necrotic_tissue
owl:sameAs
yago-res:Dystrophic_calcification wikidata:Q3650238 dbpedia-ar:تكلس_ضموري_(أنسجة) n18:3NRWy dbpedia-it:Calcificazione_distrofica freebase:m.042mcz
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dbt:Short_description dbt:Electrolyte_abnormalities dbt:Reflist
dbo:thumbnail
n12:Amyloidosis,_dystrophic_calcification,_H&E.jpg?width=300
dbo:abstract
La calcificazione distrofica in campo medico, è il processo patologico di deposito del calcio in tessuti necrotici o in via di degenerazione. Questi più frequentemente sono valvole cardiache, cicatrici e vasi sanguigni aterosclerotici. A differenza della calcificazione metastatica qui non si mostrano ipercalcemia, o alterazioni del metabolismo del calcio. Dystrophic calcification (DC) is the calcification occurring in degenerated or necrotic tissue, as in hyalinized scars, degenerated foci in leiomyomas, and caseous nodules. This occurs as a reaction to tissue damage, including as a consequence of medical device implantation. Dystrophic calcification can occur even if the amount of calcium in the blood is not elevated (a systemic mineral imbalance would elevate calcium levels in the blood and all tissues) and cause metastatic calcification. Basophilic calcium salt deposits aggregate, first in the mitochondria, then progressively throughout the cell. These calcifications are an indication of previous microscopic cell injury, occurring in areas of cell necrosis when activated phosphatases bind calcium ions to phospholipids in the membrane. التكلس الضمور ( DC ) هو التكلس الذي يحدث في الأنسجة المتدهورة أو النخرية، كما هو الحال في الندوب المتحللة، والبؤر المتدهورة في الورم العضلي الأملس، والعقيدات الجبنية. يحدث هذا كرد فعل لتلف الأنسجة، بما في ذلك نتيجة زرع جهاز طبي. يمكن أن يحدث تكلس ضمور حتى لو لم ترتفع كمية الكالسيوم في الدم (يؤدي اختلال التوازن المعدني الجهازي إلى ارتفاع مستويات الكالسيوم في الدم وجميع الأنسجة) ويسبب تكلسًا نقليًا . تتجمع رواسب ملح الكالسيوم القاعدية ، أولاً في الميتوكوندريا، ثم تدريجياً في جميع أنحاء الخلية. هذه التكلسات هي مؤشر على إصابة الخلايا المجهرية السابقة، والتي تحدث في مناطق نخر الخلية عندما تربط الفوسفاتازات المنشطة أيونات الكالسيوم بالفوسفوليبيدات في الغشاء.
gold:hypernym
dbr:Calcification
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wikipedia-en:Dystrophic_calcification?oldid=1062816036&ns=0
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wikipedia-en:Dystrophic_calcification