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Statements

Subject Item
dbr:Hookworm_vaccine
rdf:type
yago:Antigen115037339 dbo:Drug yago:Matter100020827 yago:Substance100020090 yago:WikicatVaccines yago:Vaccine104517535 yago:PhysicalEntity100001930 yago:Immunogen103562739
rdfs:label
Hookworm vaccine Hakenwurmimpfstoff
rdfs:comment
Ein Hakenwurmimpfstoff ist ein Impfstoff gegen Hakenwürmer. Hookworm vaccine is a vaccine against hookworm. No effective vaccine for the disease in humans has yet been developed. Hookworms, parasitic nematodes transmitted in soil, infect approximately 700 million humans, particularly in tropical regions of the world where endemic hookworms include Ancylostoma duodenale and Necator americanus. Hookworms feed on blood and those infected with hookworms may develop chronic anaemia and malnutrition. Helminth infection can be effectively treated with benzimidazole drugs (such as mebendazole or albendazole), and efforts led by the World Health Organization have focused on one to three yearly de-worming doses in schools because hookworm infections with the heaviest intensities are most common in school-age children. However, these drugs only eliminate exis
foaf:depiction
n12:Hookworm_LifeCycle.gif n12:Hookworms.jpg
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dbc:Vaccines
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dbo:thumbnail
n12:Hookworms.jpg?width=300
dbo:abstract
Ein Hakenwurmimpfstoff ist ein Impfstoff gegen Hakenwürmer. Hookworm vaccine is a vaccine against hookworm. No effective vaccine for the disease in humans has yet been developed. Hookworms, parasitic nematodes transmitted in soil, infect approximately 700 million humans, particularly in tropical regions of the world where endemic hookworms include Ancylostoma duodenale and Necator americanus. Hookworms feed on blood and those infected with hookworms may develop chronic anaemia and malnutrition. Helminth infection can be effectively treated with benzimidazole drugs (such as mebendazole or albendazole), and efforts led by the World Health Organization have focused on one to three yearly de-worming doses in schools because hookworm infections with the heaviest intensities are most common in school-age children. However, these drugs only eliminate existing adult parasites and re-infection can occur soon after treatment. School-based de-worming efforts do not treat adults or pre-school children and concerns exist about drug resistance developing in hookworms against the commonly used treatments, thus a vaccine against hookworm disease is sought to provide more permanent resistance to infection. Hookworm infection is considered a neglected disease as it disproportionately affects poorer localities and has received little attention from pharmaceutical companies.
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dbr:Vaccine
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