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Princípio de Krogh Principio de Krogh Krogh's principle 克罗原则
rdfs:comment
克罗原则（Krogh's principle）是生物学中的一个原则，指对大多数问题，总会有某种动物最适合于这一问题的研究。这一原则在依赖比较方法的领域，如神经行为学、、等中，都有广泛的应用。 克罗原则是以丹麦生理学家、诺贝尔奖得主奥古斯特·克罗的名字命名的。1975年，另一诺贝尔奖得主、生物化学家汉斯·阿道夫·克雷布斯最早使用了这一术语。 El principio de Krogh establece que "para un número tan grande de problemas habrá algún animal de elección, o algunos animales de este tipo, en los que se pueda estudiar más convenientemente". Este concepto es fundamental para aquellas disciplinas de la biología que se basan en el método comparativo, como la neuroetología, la fisiología comparada y, más recientemente, la genómica funcional. O princípio de Krogh afirma que "para cada problema fisiológico existe um animal-modelo adequado ao seu estudo". Este conceito é central para aquelas disciplinas da biologia que se amparam no método comparativo tais como a neuroetologia, a e mais recentemente a genómica funcional. Krogh's principle states that "for such a large number of problems there will be some animal of choice, or a few such animals, on which it can be most conveniently studied." This concept is central to those disciplines of biology that rely on the comparative method, such as neuroethology, comparative physiology, and more recently functional genomics.
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August Krogh Claude Bernard
dbp:source
The American Journal of Physiology, 1929. 90 pp. 243-251 J.B. Baillière et Fils, Libraires de L'Académie Impériale de Médecine, 1865. pp. 400
dbp:text
Dans l'investigation scientifique, les moindres procédés sont de la plus haute importance. Le choix heureux d'un animal, d'un instrument construit d'une certaine façon, l'emploi d'un réactif au lieu d'un autre, suffisent souvent pour résoudre les questions générales les plus élevées. ...I want to emphasize that the route by which we can strive toward the ideal is by a study of the vital functions in all their aspects throughout the myriads of organisms. We may find out, nay, we will find out before very long the essential mechanisms of mammalian kidney function, but the general problem of excretion can be solved only when excretory organs are studied wherever we find them and in all their essential modifications. Such studies will be sure, moreover, to expand and deepen our insight into problems of the human kidney and will prove of value also from the narrowest utilitarian point of view. For such a large number of problems there will be some animal of choice or a few such animals on which it can be most conveniently studied. Many years ago when my teacher, Christian Bohr, was interested in the respiratory mechanism of the lung and devised the method of studying the exchange through each lung separately, he found that a certain kind of tortoise possessed a trachea dividing into the main bronchi high up in the neck, and we used to say as a laboratory joke that this animal had been created expressly for the purposes of respiration physiology. I have no doubt that there is quite a number of animals which are similarly "created" for special physiological purposes, but I am afraid that most of them are unknown to the men for whom they were "created," and we must apply to the zoologists to find them and lay our hands on them."
dbp:title
Introduction à l'étude de la médecine expérimentale The Progress of Physiology
dbo:abstract
El principio de Krogh establece que "para un número tan grande de problemas habrá algún animal de elección, o algunos animales de este tipo, en los que se pueda estudiar más convenientemente". Este concepto es fundamental para aquellas disciplinas de la biología que se basan en el método comparativo, como la neuroetología, la fisiología comparada y, más recientemente, la genómica funcional. 克罗原则（Krogh's principle）是生物学中的一个原则，指对大多数问题，总会有某种动物最适合于这一问题的研究。这一原则在依赖比较方法的领域，如神经行为学、、等中，都有广泛的应用。 克罗原则是以丹麦生理学家、诺贝尔奖得主奥古斯特·克罗的名字命名的。1975年，另一诺贝尔奖得主、生物化学家汉斯·阿道夫·克雷布斯最早使用了这一术语。 Krogh's principle states that "for such a large number of problems there will be some animal of choice, or a few such animals, on which it can be most conveniently studied." This concept is central to those disciplines of biology that rely on the comparative method, such as neuroethology, comparative physiology, and more recently functional genomics. O princípio de Krogh afirma que "para cada problema fisiológico existe um animal-modelo adequado ao seu estudo". Este conceito é central para aquelas disciplinas da biologia que se amparam no método comparativo tais como a neuroetologia, a e mais recentemente a genómica funcional.
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