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Statements

Subject Item
dbr:Pertussis_toxin
rdf:type
yago:Unit108189659 yago:Abstraction100002137 dbo:Biomolecule yago:Family108078020 yago:YagoLegalActor yago:YagoLegalActorGeo yago:YagoPermanentlyLocatedEntity yago:Organization108008335 wikidata:Q8054 owl:Thing wikidata:Q206229 yago:Group100031264 dbo:Protein yago:WikicatProteinFamilies yago:SocialGroup107950920
rdfs:label
Pertussis-Toxin 百日咳毒素 Pertussis toxin Pertussistoxin Toxina pertussis
rdfs:comment
Das Pertussis-Toxin (PT) ist ein Protein, das von dem Bakterium Bordetella pertussis hergestellt und an seine Umgebung abgegeben wird (Exotoxin). Es ist ursächlich für die Krankheitssymptome des Keuchhustens. La toxina Pertussis (PT) es una exotoxina formada a base de proteínas producida por la bacteria Bordetella pertussis.​ PT está involucrada en la colonización del tracto respiratorio y el establecimiento de la infección. Diversas investigaciones sugieren que PT puede desempeñar un papel terapéutico en cierto número de dolencias humanas comunes tales como la hipertensión,​ inhibición viral​ e inhibición autoinmune.​ Pertussis toxin (PT) is a protein-based AB5-type exotoxin produced by the bacterium Bordetella pertussis, which causes whooping cough. PT is involved in the colonization of the respiratory tract and the establishment of infection. Research suggests PT may have a therapeutic role in treating a number of common human ailments, including hypertension, viral infection, and autoimmunity. 百日咳毒素(ひゃくにちぜきどくそ、英: pertussis toxin、略称: PT)とは、百日咳の原因である百日咳菌(Bordetella pertussis)によって産生される毒素であり、百日咳菌の気管上皮への付着等に働いているとされる。作用機序としては3量体Gタンパク質のαiサブユニットに対するADPリボース転位酵素活性を持っている。 Pertussistoxin (PT) är ett exotoxin som utsöndras av bakterien Bordetella pertussis. Toxinet gör att epitelvävnaden i de övre luftvägarna blir känsliga för histamin och serotonin, och orsakar kikhosta hos den patient som infekterats med bakterien.
dbp:name
Pertussis toxin, subunit 5 Pertussis toxin, subunit 1 Pertussis toxin, subunit 4 Pertussis toxin, subunit 2 and 3
foaf:depiction
n26:Pertussis_toxin_complex.png
dct:subject
dbc:AB5_toxins dbc:Protein_families dbc:Whooping_cough dbc:Signal_transduction
dbo:wikiPageID
2864360
dbo:wikiPageRevisionID
1105110859
dbo:wikiPageWikiLink
dbr:Bordetella_pertussis dbr:ADP-ribosylation dbr:Chemotaxis dbr:Pertussis dbc:AB5_toxins dbr:Cell_membrane dbr:Gi_alpha_subunit dbr:Hypoglycemia dbr:Bordetella_parapertussis dbr:Endoplasmic_reticulum dbr:Macrophages dbr:AB5_toxin dbr:Operon dbr:Bordetella dbr:Lysine dbr:CyaA dbr:Insulin dbc:Protein_families dbc:Whooping_cough dbr:Exotoxin dbr:G_protein-coupled_receptor dbr:Glutathione dbr:Pathogenesis dbr:Chemokine dbr:Guillaume_de_Baillou dbr:Heterotrimeric_G_protein dbr:Ubiquitin dbc:Signal_transduction dbr:Trans-Golgi_network dbr:Adenosine_triphosphate dbr:Receptor_(biochemistry) dbr:ERAD dbr:Lymphocytosis dbr:Neutrophils dbr:Respiratory_tract dbr:Endosome dbr:CXCL5 dbr:Proteasome dbr:Enzyme dbr:Pasteur_Institute dbr:Whooping_cough dbr:Bacterium
owl:sameAs
wikidata:Q4859345 yago-res:Pertussis_toxin dbpedia-ja:百日咳毒素 freebase:m.087nwt dbpedia-sr:Pertuzijski_toksin n17:4Vn2j dbpedia-sh:Pertuzijski_toksin dbpedia-sl:Toksin_oslovskega_kašlja dbpedia-es:Toxina_pertussis dbpedia-sv:Pertussistoxin dbpedia-de:Pertussis-Toxin
dbp:wikiPageUsesTemplate
dbt:Pfam_box dbt:Short_description dbt:Glycosyltransferases dbt:Toxins dbt:Reflist
dbo:thumbnail
n26:Pertussis_toxin_complex.png?width=300
dbp:scop
1
dbp:caption
The crystal structure of pertussis toxin,
dbp:interpro
IPR015355 IPR003898 IPR015356 IPR003899
dbp:pfam
PF02918 PF02917 PF09275 PF09276
dbp:symbol
Pertus-S5-tox Pertussis_S2S3 Pertussis_S1 Pertus-S4-tox
dbo:abstract
Das Pertussis-Toxin (PT) ist ein Protein, das von dem Bakterium Bordetella pertussis hergestellt und an seine Umgebung abgegeben wird (Exotoxin). Es ist ursächlich für die Krankheitssymptome des Keuchhustens. 百日咳毒素(ひゃくにちぜきどくそ、英: pertussis toxin、略称: PT)とは、百日咳の原因である百日咳菌(Bordetella pertussis)によって産生される毒素であり、百日咳菌の気管上皮への付着等に働いているとされる。作用機序としては3量体Gタンパク質のαiサブユニットに対するADPリボース転位酵素活性を持っている。 Pertussis toxin (PT) is a protein-based AB5-type exotoxin produced by the bacterium Bordetella pertussis, which causes whooping cough. PT is involved in the colonization of the respiratory tract and the establishment of infection. Research suggests PT may have a therapeutic role in treating a number of common human ailments, including hypertension, viral infection, and autoimmunity. Pertussistoxin (PT) är ett exotoxin som utsöndras av bakterien Bordetella pertussis. Toxinet gör att epitelvävnaden i de övre luftvägarna blir känsliga för histamin och serotonin, och orsakar kikhosta hos den patient som infekterats med bakterien. La toxina Pertussis (PT) es una exotoxina formada a base de proteínas producida por la bacteria Bordetella pertussis.​ PT está involucrada en la colonización del tracto respiratorio y el establecimiento de la infección. Diversas investigaciones sugieren que PT puede desempeñar un papel terapéutico en cierto número de dolencias humanas comunes tales como la hipertensión,​ inhibición viral​ e inhibición autoinmune.​
gold:hypernym
dbr:Exotoxin
prov:wasDerivedFrom
wikipedia-en:Pertussis_toxin?oldid=1105110859&ns=0
dbo:wikiPageLength
23354
dbo:symbol
Pertussis_S2S3 Pertus-S5-tox Pertussis_S1 Pertus-S4-tox
foaf:isPrimaryTopicOf
wikipedia-en:Pertussis_toxin