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Statements

Subject Item
dbr:Piperidione
rdf:type
umbel-rc:DrugProduct dbo:ChemicalSubstance yago:Substance100020090 n17:ChemicalObject dbo:Drug yago:DrugOfAbuse103248958 yago:Matter100020827 yago:CausalAgent100007347 yago:Agent114778436 yago:Drug103247620 yago:Medicine103740161 yago:Antitussive102725242 owl:Thing wikidata:Q8386 yago:WikicatSedatives yago:WikicatAntitussives yago:Sedative104166553 yago:PhysicalEntity100001930
rdfs:label
Piperidione
rdfs:comment
Piperidione (trade name Sedulon) is a sedative drug, structurally related to methyprylon and pyrithyldione.It used to be marketed by Roche as a cough medicine available in liquid form. In the US, it was approved by the FDA on grounds of safety alone in 1947. After Roche failed to submit evidence of efficacy to the Drug Efficacy Study Implementation program in 1972, it was withdrawn from the US market.
foaf:depiction
n15:Piperidione.png n15:Piperidione_ball-and-stick.png
dcterms:subject
dbc:4-Piperidinones dbc:Sedatives dbc:Withdrawn_drugs dbc:GABAA_receptor_positive_allosteric_modulators dbc:Antitussives dbc:2-Piperidinones
dbo:wikiPageID
12285409
dbo:wikiPageRevisionID
1097349853
dbo:wikiPageWikiLink
dbr:Glutethimide dbc:2-Piperidinones dbc:4-Piperidinones dbr:Hoffmann-La_Roche dbc:Sedatives dbc:Withdrawn_drugs dbr:Pyrithyldione dbr:Methyprylon dbr:Sedative dbc:GABAA_receptor_positive_allosteric_modulators dbr:Cough_suppressant dbr:Drug_Efficacy_Study_Implementation dbc:Antitussives
owl:sameAs
dbpedia-sh:Piperidion dbpedia-fa:پیپریدیون freebase:m.02vyzjw n19:4tfMv wikidata:Q7197355 dbpedia-sr:Piperidion n22:பைப்பெரிடையோன் yago-res:Piperidione
dbp:wikiPageUsesTemplate
dbt:Cough_and_cold_preparations dbt:Fdacite dbt:Stdinchicite dbt:Respiratory-system-drug-stub dbt:Drugbox dbt:Drugbankcite dbt:GABAAR_PAMs dbt:Reflist dbt:Chemspidercite dbt:Hypnotics_and_sedatives dbt:Cascite
dbo:thumbnail
n15:Piperidione.png?width=300
dbp:atcSuffix
DB23
dbp:atcPrefix
R05
dbp:c
9
dbp:casNumber
77
dbp:chemspiderid
6222
dbp:h
15
dbp:image
Piperidione ball-and-stick.png
dbp:iupacName
33
dbp:n
1
dbp:o
2
dbp:pubchem
6465
dbp:smiles
O=C1CCC
dbp:stdinchi
1
dbp:stdinchikey
RGEVWUKXWFOAID-UHFFFAOYSA-N
dbp:tradename
Ascron, Dihyprylon, Dihyprylone, Sedulon, Tusseval
dbp:unii
BZ6KL0Q8UD
dbp:verifiedfields
changed
dbp:verifiedrevid
464207558
dbp:width
120 180
dbo:abstract
Piperidione (trade name Sedulon) is a sedative drug, structurally related to methyprylon and pyrithyldione.It used to be marketed by Roche as a cough medicine available in liquid form. In the US, it was approved by the FDA on grounds of safety alone in 1947. After Roche failed to submit evidence of efficacy to the Drug Efficacy Study Implementation program in 1972, it was withdrawn from the US market.
gold:hypernym
dbr:Drug
prov:wasDerivedFrom
wikipedia-en:Piperidione?oldid=1097349853&ns=0
dbo:wikiPageLength
3493
dbo:alternativeName
Ascron, Dihyprylon, Dihyprylone, Sedulon, Tusseval
dbo:casNumber
77-03-2
dbo:fdaUniiCode
BZ6KL0Q8UD
dbo:pubchem
6465
foaf:isPrimaryTopicOf
wikipedia-en:Piperidione