. . . "L'ACTA2 (pour \u00AB actine alpha 2 \u00BB) est l'une des isoforme de l'actine. Son g\u00E8ne est ACTA2 situ\u00E9 sur le chromosome 10 humain."@fr . . . . "L'ACTA2 (pour \u00AB actine alpha 2 \u00BB) est l'une des isoforme de l'actine. Son g\u00E8ne est ACTA2 situ\u00E9 sur le chromosome 10 humain."@fr . . "14754358"^^ . . . . . . . . . "ACTA2"@en . . . . . "\u0410\u043B\u044C\u0444\u0430-\u0430\u043A\u0442\u0438\u043D 2 (\u0430\u043D\u0433\u043B. Actin, alpha 2, smooth muscle, aorta) \u2013 \u0431\u0456\u043B\u043E\u043A, \u044F\u043A\u0438\u0439 \u043A\u043E\u0434\u0443\u0454\u0442\u044C\u0441\u044F \u0433\u0435\u043D\u043E\u043C ACTA2, \u0440\u043E\u0437\u0442\u0430\u0448\u043E\u0432\u0430\u043D\u0438\u043C \u0443 \u043B\u044E\u0434\u0435\u0439 \u043D\u0430 \u043A\u043E\u0440\u043E\u0442\u043A\u043E\u043C\u0443 \u043F\u043B\u0435\u0447\u0456 10-\u0457 \u0445\u0440\u043E\u043C\u043E\u0441\u043E\u043C\u0438. \u0414\u043E\u0432\u0436\u0438\u043D\u0430 \u043F\u043E\u043B\u0456\u043F\u0435\u043F\u0442\u0438\u0434\u043D\u043E\u0433\u043E \u043B\u0430\u043D\u0446\u044E\u0433\u0430 \u0431\u0456\u043B\u043A\u0430 \u0441\u0442\u0430\u043D\u043E\u0432\u0438\u0442\u044C 377 \u0430\u043C\u0456\u043D\u043E\u043A\u0438\u0441\u043B\u043E\u0442, \u0430 \u043C\u043E\u043B\u0435\u043A\u0443\u043B\u044F\u0440\u043D\u0430 \u043C\u0430\u0441\u0430 \u2014 42 009. \u041F\u043E\u0441\u043B\u0456\u0434\u043E\u0432\u043D\u0456\u0441\u0442\u044C \u0430\u043C\u0456\u043D\u043E\u043A\u0438\u0441\u043B\u043E\u0442 A: \u0410\u043B\u0430\u043D\u0456\u043DC: \u0426\u0438\u0441\u0442\u0435\u0457\u043DD: \u0410\u0441\u043F\u0430\u0440\u0430\u0433\u0456\u043D\u043E\u0432\u0430 \u043A\u0438\u0441\u043B\u043E\u0442\u0430E: \u0413\u043B\u0443\u0442\u0430\u043C\u0456\u043D\u043E\u0432\u0430 \u043A\u0438\u0441\u043B\u043E\u0442\u0430F: \u0424\u0435\u043D\u0456\u043B\u0430\u043B\u0430\u043D\u0456\u043DG: \u0413\u043B\u0456\u0446\u0438\u043DH: \u0413\u0456\u0441\u0442\u0438\u0434\u0438\u043DI: \u0406\u0437\u043E\u043B\u0435\u0439\u0446\u0438\u043DK: \u041B\u0456\u0437\u0438\u043DL: \u041B\u0435\u0439\u0446\u0438\u043DM: \u041C\u0435\u0442\u0456\u043E\u043D\u0456\u043DN: \u0410\u0441\u043F\u0430\u0440\u0430\u0433\u0456\u043DP: \u041F\u0440\u043E\u043B\u0456\u043DQ: \u0413\u043B\u0443\u0442\u0430\u043C\u0456\u043DR: \u0410\u0440\u0433\u0456\u043D\u0456\u043DS: \u0421\u0435\u0440\u0438\u043DT: \u0422\u0440\u0435\u043E\u043D\u0456\u043DV: \u0412\u0430\u043B\u0456\u043DW: \u0422\u0440\u0438\u043F\u0442\u043E\u0444\u0430\u043D Y: \u0422\u0438\u0440\u043E\u0437\u0438\u043D \u0426\u0435\u0439 \u0431\u0456\u043B\u043E\u043A \u0437\u0430 \u0444\u0443\u043D\u043A\u0446\u0456\u0454\u044E \u043D\u0430\u043B\u0435\u0436\u0438\u0442\u044C \u0434\u043E . \u0411\u0456\u043B\u043E\u043A \u043C\u0430\u0454 \u0441\u0430\u0439\u0442 \u0434\u043B\u044F \u0437\u0432'\u044F\u0437\u0443\u0432\u0430\u043D\u043D\u044F \u0437 \u0410\u0422\u0424, \u043D\u0443\u043A\u043B\u0435\u043E\u0442\u0438\u0434\u0430\u043C\u0438. \u041B\u043E\u043A\u0430\u043B\u0456\u0437\u043E\u0432\u0430\u043D\u0438\u0439 \u0443 \u0446\u0438\u0442\u043E\u043F\u043B\u0430\u0437\u043C\u0456, \u0446\u0438\u0442\u043E\u0441\u043A\u0435\u043B\u0435\u0442\u0456."@uk . . . . "ACTA2\u200F (Actin, alpha 2, smooth muscle, aorta) \u0647\u0648\u064E \u0628\u0631\u0648\u062A\u064A\u0646 \u064A\u064F\u0634\u064E\u0641\u0631 \u0628\u0648\u0627\u0633\u0637\u0629 \u062C\u064A\u0646 ACTA2 \u0641\u064A \u0627\u0644\u0625\u0646\u0633\u0627\u0646."@ar . . . . . . "ACTA2 es un gen humano que codifica para la alfa actina 2 situado en el cromosoma 10. Esta isoforma de actina es propia del m\u00FAsculo esquel\u00E9tico y los alelos que disminuyen su funci\u00F3n ocasionan un tipo de aneurisma tor\u00E1cico. Existen varias variantes de splicing alternativo. La alfa actina de m\u00FAsculo liso puede emplearse como marcador para evaluar la progresi\u00F3n de la cirrosis hep\u00E1tica.\u200B"@es . . "ACTA2"@ar . . . . . . . . . . "ACTA2"@fr . . "\u0410\u043B\u044C\u0444\u0430-\u0430\u043A\u0442\u0438\u043D 2"@uk . . . . "ACTA2 (actin alpha 2) is an actin protein with several aliases including alpha-actin, alpha-actin-2, aortic smooth muscle or alpha smooth muscle actin (\u03B1-SMA, SMactin, alpha-SM-actin, ASMA). Actins are a family of globular multi-functional proteins that form microfilaments. ACTA2 is one of 6 different actin isoforms and is involved in the contractile apparatus of smooth muscle. ACTA2 (as with all the actins) is extremely highly conserved and found in nearly all mammals."@en . "ACTA2\u200F (Actin, alpha 2, smooth muscle, aorta) \u0647\u0648\u064E \u0628\u0631\u0648\u062A\u064A\u0646 \u064A\u064F\u0634\u064E\u0641\u0631 \u0628\u0648\u0627\u0633\u0637\u0629 \u062C\u064A\u0646 ACTA2 \u0641\u064A \u0627\u0644\u0625\u0646\u0633\u0627\u0646."@ar . . . . . "ACTA2"@es . . . . . . . . . . . . . . . . "1115901224"^^ . . . "\u0410\u043B\u044C\u0444\u0430-\u0430\u043A\u0442\u0438\u043D 2 (\u0430\u043D\u0433\u043B. Actin, alpha 2, smooth muscle, aorta) \u2013 \u0431\u0456\u043B\u043E\u043A, \u044F\u043A\u0438\u0439 \u043A\u043E\u0434\u0443\u0454\u0442\u044C\u0441\u044F \u0433\u0435\u043D\u043E\u043C ACTA2, \u0440\u043E\u0437\u0442\u0430\u0448\u043E\u0432\u0430\u043D\u0438\u043C \u0443 \u043B\u044E\u0434\u0435\u0439 \u043D\u0430 \u043A\u043E\u0440\u043E\u0442\u043A\u043E\u043C\u0443 \u043F\u043B\u0435\u0447\u0456 10-\u0457 \u0445\u0440\u043E\u043C\u043E\u0441\u043E\u043C\u0438. \u0414\u043E\u0432\u0436\u0438\u043D\u0430 \u043F\u043E\u043B\u0456\u043F\u0435\u043F\u0442\u0438\u0434\u043D\u043E\u0433\u043E \u043B\u0430\u043D\u0446\u044E\u0433\u0430 \u0431\u0456\u043B\u043A\u0430 \u0441\u0442\u0430\u043D\u043E\u0432\u0438\u0442\u044C 377 \u0430\u043C\u0456\u043D\u043E\u043A\u0438\u0441\u043B\u043E\u0442, \u0430 \u043C\u043E\u043B\u0435\u043A\u0443\u043B\u044F\u0440\u043D\u0430 \u043C\u0430\u0441\u0430 \u2014 42 009. \u041F\u043E\u0441\u043B\u0456\u0434\u043E\u0432\u043D\u0456\u0441\u0442\u044C \u0430\u043C\u0456\u043D\u043E\u043A\u0438\u0441\u043B\u043E\u0442 A: \u0410\u043B\u0430\u043D\u0456\u043DC: \u0426\u0438\u0441\u0442\u0435\u0457\u043DD: \u0410\u0441\u043F\u0430\u0440\u0430\u0433\u0456\u043D\u043E\u0432\u0430 \u043A\u0438\u0441\u043B\u043E\u0442\u0430E: \u0413\u043B\u0443\u0442\u0430\u043C\u0456\u043D\u043E\u0432\u0430 \u043A\u0438\u0441\u043B\u043E\u0442\u0430F: \u0424\u0435\u043D\u0456\u043B\u0430\u043B\u0430\u043D\u0456\u043DG: \u0413\u043B\u0456\u0446\u0438\u043DH: \u0413\u0456\u0441\u0442\u0438\u0434\u0438\u043DI: \u0406\u0437\u043E\u043B\u0435\u0439\u0446\u0438\u043DK: \u041B\u0456\u0437\u0438\u043DL: \u041B\u0435\u0439\u0446\u0438\u043DM: \u041C\u0435\u0442\u0456\u043E\u043D\u0456\u043DN: \u0410\u0441\u043F\u0430\u0440\u0430\u0433\u0456\u043DP: \u041F\u0440\u043E\u043B\u0456\u043DQ: \u0413\u043B\u0443\u0442\u0430\u043C\u0456\u043DR: \u0410\u0440\u0433\u0456\u043D\u0456\u043DS: \u0421\u0435\u0440\u0438\u043DT: \u0422\u0440\u0435\u043E\u043D\u0456\u043DV: \u0412\u0430\u043B\u0456\u043DW: \u0422\u0440\u0438\u043F\u0442\u043E\u0444\u0430\u043D Y: \u0422\u0438\u0440\u043E\u0437\u0438\u043D"@uk . "9434"^^ . "ACTA2 es un gen humano que codifica para la alfa actina 2 situado en el cromosoma 10. Esta isoforma de actina es propia del m\u00FAsculo esquel\u00E9tico y los alelos que disminuyen su funci\u00F3n ocasionan un tipo de aneurisma tor\u00E1cico. Existen varias variantes de splicing alternativo. La alfa actina de m\u00FAsculo liso puede emplearse como marcador para evaluar la progresi\u00F3n de la cirrosis hep\u00E1tica.\u200B"@es . . . . . . . . . . . "ACTA2 (actin alpha 2) is an actin protein with several aliases including alpha-actin, alpha-actin-2, aortic smooth muscle or alpha smooth muscle actin (\u03B1-SMA, SMactin, alpha-SM-actin, ASMA). Actins are a family of globular multi-functional proteins that form microfilaments. ACTA2 is one of 6 different actin isoforms and is involved in the contractile apparatus of smooth muscle. ACTA2 (as with all the actins) is extremely highly conserved and found in nearly all mammals. In humans, ACTA2 is encoded by the ACTA2 gene located on 10q22-q24. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, Moyamoya disease, and multisystemic smooth muscle dysfunction syndrome. ACTA2 (commonly referred to as alpha-smooth muscle actin or \u03B1-SMA) is often used as a marker of myofibroblast formation. Studies have shown that ACTA2 is associated with TGF \u03B2 pathway that enhances contractile properties of Hepatic Stellate Cells leading to liver fibrosis and cirrhosis."@en . . .