. . . "Smoking, high blood pressure, high cholesterol, diabetes, being male"@en . . . . "\u0421\u0442\u0435\u043D\u043E\u0437 \u0430\u043E\u0440\u0442\u0430\u043B\u044C\u043D\u043E\u0433\u043E \u043A\u043B\u0430\u043F\u0430\u043D\u0430"@uk . "Aortastenos eller aortaklaffsstenos inneb\u00E4r en f\u00F6rtr\u00E4ngning av utfl\u00F6det fr\u00E5n v\u00E4nster hj\u00E4rtkammare (f\u00F6rbi aortaklaffen) till den grad att det orsakar olika problem. Prevalensen \u00E4r 0,2 % 50-60 \u00E5ringar men kring 10 % hos personer \u00F6ver 80 \u00E5r . Aortastenos kan uppst\u00E5 i niv\u00E5 med aortaklaffen, men kan \u00E4ven bero p\u00E5 f\u00F6rtr\u00E4ngning \u00F6ver eller under denna niv\u00E5. Vanligen f\u00F6rv\u00E4rras stenosen \u00F6ver tid. Symptom uppkommer ofta successivt med en minskad f\u00F6rm\u00E5ga till anstr\u00E4ngning som vanligaste debutsymptom. Om hj\u00E4rtsvikt, medvetandef\u00F6rlust, eller k\u00E4rlkramp uppst\u00E5r \u00E4r det tecken p\u00E5 en allvarligare sjukdomsgrad. Svimning eller medvetandef\u00F6rlust intr\u00E4ffar vanligen d\u00E5 personen st\u00E4llt sig upp eller vid motion. Symptom p\u00E5 hj\u00E4rtsvikt kan vara andn\u00F6d som \u00E4r s\u00E4rskilt uttalad d\u00E5 man ligger ner, p\u00E5 natten, eller som uppkommer med motion. \u00C4ven bensvullnad har en koppling till aortastenos. F\u00F6rtjockning av hj\u00E4rtklaffen utan f\u00F6rtr\u00E4ngning kallas aortaskleros. Orsaker till aortastenos kan vara en medf\u00F6dd bikuspid aortaklaff (tv\u00E5- ist\u00E4llet f\u00F6r tredelad) och reumatisk feber. En bikuspid aortaklaff f\u00F6rekommer hos cirka en till tv\u00E5 procent av befolkningen medan reumatisk hj\u00E4rtsjukdom framf\u00F6rallt drabbar individer i utvecklingsl\u00E4nder. En fullt normal ursprungligen frisk klaff kan \u00E4ven h\u00E5rdna och bli stenotisk \u00F6ver tid efter flera decennier. Riskfaktorer f\u00F6r aortastenos \u00E4r mycket lika de f\u00F6r kransk\u00E4rlssjukdom och innefattar r\u00F6kning, h\u00F6gt blodtryck, h\u00F6gt kolesterol, diabetes och manligt k\u00F6n. Aortaklaffen best\u00E5r vanligen av tre \"fickor\" och ligger mellan v\u00E4nster kammare i hj\u00E4rtat och stora kroppspuls\u00E5dern (aorta). En aortastenos kan oftast h\u00F6ras som ett bl\u00E5sljud p\u00E5 hj\u00E4rtat om man lyssnar med t.ex. stetoskop. Utifr\u00E5n ultraljud av hj\u00E4rtat kan man indela sjukdomen i olika sv\u00E5righetsgrader som mild, m\u00E5ttlig, sv\u00E5r och mycket sv\u00E5r. Aortastenos f\u00F6ljs vanligen av upprepade ultraljudsunders\u00F6kningar. S\u00E5 l\u00E4nge sjukdomen \u00E4r asymtomatisk ses ingen \u00F6kad d\u00F6dlighet men om sjukdomen b\u00F6rjar att ge symtom \u00E4r den obehandlade tv\u00E5-\u00E5rs-d\u00F6dligheten kring 50 procent. Det finns ingen botande l\u00E4kemedelsbehandling utan om sjukdomen uppn\u00E5tt en sv\u00E5r sv\u00E5righetsgrad best\u00E5r behandlingen i f\u00F6rsta hand av \u00F6ppen kirurgi d\u00E4r man byter ut aortaklaffen. Hos patienter med sv\u00E5r eller medelh\u00F6g risk finns kateterburen aortaklaffimplantation (TAVI) som ett alternativ. Nyare studier har visat likv\u00E4rdiga resultat mot \u00F6ppen kirurgi \u00E4ven hos patienter med medelh\u00F6g kirurgisk risk . Klaffen ers\u00E4tts med antingen mekaniska eller biologiska proteser, b\u00E4gge med vissa risker och f\u00F6rdelar. Ett mindre invasivt ingrepp kallat BAV (balloon aorta valvuloplasty) kan vara till hj\u00E4lp men \u00E4r i regel endast en kortvarig l\u00F6sning. Komplikationer som hj\u00E4rtsvikt kan behandlas som vanligt bland de med mild eller medelsv\u00E5r aortastenos. Bland de med sv\u00E5r sjukdom finns ett antal mediciner som b\u00F6r undvikas, s\u00E5som ACE-h\u00E4mmare, nitroglycerin, och vissa beta-blockerare. Nitroprussid eller fenylefrin kan anv\u00E4ndas f\u00F6r de med okompenserad hj\u00E4rtsvikt med h\u00E4nsyn till blodtrycket. Aortastenos \u00E4r den vanligaste hj\u00E4rtklaffsjukdomen i den utvecklade v\u00E4rlden. Aortastenos drabbar ca 2 % av befolkningen som \u00E4r \u00F6ver 65 \u00E5r. F\u00F6rekomst av aortastenos \u00E4r ok\u00E4nd i de flesta av utvecklingsl\u00E4nderna enligt statistik fr\u00E5n 2014. Aortastenos beskrevs f\u00F6rsta g\u00E5ngen av den franske l\u00E4karen Lazare Rivi\u00E8re 1663."@sv . . "Aortastenose is een vernauwing van de uitstroomopening van de linkerhartkamer. Meestal wordt dit veroorzaakt door een aandoening aan de aortaklep. Bij deze aortaklepstenose is er een stenose (vernauwing) van de aortaklep, die daardoor niet wijd genoeg open kan. Bij een aortastenose kan een drukgradi\u00EBnt over de klep ontstaan. De linkerventrikel moet daardoor hogere drukken genereren om bloed in de aorta te krijgen. Er ontstaat op den duur linkerventrikelhypertrofie door drukbelasting."@nl . . . . . . . . . "\u5927\u52D5\u8108\u5F01\u72ED\u7A84\u75C7\uFF08\u3060\u3044\u3069\u3046\u307F\u3083\u304F\u3079\u3093\u304D\u3087\u3046\u3055\u304F\u3057\u3087\u3046\u3001\u82F1Aortic valve stenosis\uFF1AAS\uFF09\u306F\u3001\u5927\u52D5\u8108\u5F01\u53E3\u306E\u72ED\u7A84\u306B\u3088\u3063\u3066\u5168\u8EAB\u306B\u8840\u6DB2\u304C\u9001\u308A\u51FA\u3055\u308C\u306B\u304F\u304F\u306A\u308B\u75BE\u60A3\u3067\u3042\u308B\u3002"@ja . . . . "\u4E3B\u52D5\u8108\u74E3\u72F9\u7A84\uFF08Aortic stenosis\uFF0C\u7C21\u7A31AS\u6216AoS\uFF09\u4E43\u63CF\u8FF0\u5DE6\u5FC3\u5BA4\u901A\u5411\u4E3B\u52D5\u8108\u7684\u74E3\u819C\u53E3\u72F9\u7A84\u7684\u73FE\u8C61\u3002\u53EF\u80FD\u662F\u7531\u4E3B\u52D5\u8108\u74E3\u7684\u7D50\u69CB\u7570\u5E38\u9020\u6210\uFF0C\u6216\u4E3B\u52D5\u8108\u74E3\u7684\u4E0A\u6E38\u6216\u4E0B\u6E38\u89E3\u5256\u7D50\u69CB\u7684\u7570\u5E38\u9020\u6210\u3002\u4E00\u822C\u4F86\u8AAA\uFF0C\u5176\u75C5\u60C5\u6703\u96A8\u6642\u9593\u6108\u767C\u52A0\u91CD\u3002\u4E00\u958B\u59CB\uFF0C\u60A3\u8005\u53EF\u80FD\u6703\u767C\u73FE\u5176\u904B\u52D5\u80FD\u529B\u6E1B\u9000\u3002\u5F8C\u96A8\u75C5\u60C5\u9032\u4E00\u6B65\u767C\u5C55\uFF0C\u53EF\u80FD\u51FA\u73FE\u5FC3\u81DF\u8870\u7AED\u3001\u660F\u53A5\u3001\u5FC3\u7D5E\u75DB\u7B49\u81E8\u5E8A\u75C7\u72C0\u8207\u9AD4\u5FB5\u3002\u660F\u53A5\u5E38\u767C\u751F\u65BC\u60A3\u8005\u7AD9\u7ACB\u6216\u904B\u52D5\u6642\uFF0C\u5FC3\u81DF\u8870\u7AED\u7684\u81E8\u5E8A\u9AD4\u5FB5\u5305\u62EC\u547C\u5438\u56F0\u96E3\uFF08\u7279\u5225\u662F\u5728\u5E73\u81E5\u3001\u591C\u665A\u6216\u904B\u52D5\u6642\uFF09\uFF0C\u4EE5\u53CA\u5916\u9031\u6027\u6C34\u816B\u3002\u4E3B\u52D5\u8108\u74E3\u819C\u8B8A\u539A\u4F46\u74E3\u819C\u53E3\u672A\u8B8A\u72F9\u7A84\u5247\u7A31\u70BA\u4E3B\u52D5\u8108\u74E3\u786C\u5316\u3002 \u81F4\u75C5\u539F\u56E0\u5305\u542B\u5148\u5929\u6027\u548C\u98A8\u6FD5\u71B1\u3002\u96D9\u8449\u6027\u52D5\u8108\u74E3\u7684\u76DB\u884C\u7387\u7D04\u70BA1-2%\uFF0C\u800C\u98A8\u6FD5\u71B1\u5247\u5927\u591A\u5F71\u97FF\u958B\u767C\u4E2D\u570B\u5BB6\u7684\u4EBA\u6C11\u3002\u5148\u5929\u6B63\u5E38\u7684\u74E3\u819C\u4E5F\u53EF\u80FD\u56E0\u5F8C\u5929\u6027\u56E0\u7D20\u786C\u5316\u3002\u98A8\u96AA\u56E0\u5B50\u8207\u51A0\u72C0\u52D5\u8108\u75BE\u75C5\u985E\u4F3C\uFF0C\u5305\u542B\u5438\u83F8\u3001\u9AD8\u8840\u58D3\u3001\u81BD\u56FA\u9187\u904E\u9AD8\uFF0C\u4EE5\u53CA\u7CD6\u5C3F\u75C5\u7B49\u3002\u6B64\u5916\uFF0C\u7537\u6027\u7F79\u60A3\u6B64\u75BE\u75C5\u7684\u98A8\u96AA\u8F03\u9AD8\u3002\u4E3B\u52D5\u8108\u74E3\u901A\u5E38\u6709\u4E09\u7247\uFF0C\u4F4D\u65BC\u5FC3\u5BA4\u53CA\u4E3B\u52D5\u8108\u4E4B\u9593\u3002\u4E3B\u52D5\u8108\u74E3\u72F9\u7A84\u6703\u7522\u751F\u5FC3\u96DC\u97F3\uFF0C\u53EF\u6839\u64DA\u8D85\u8072\u5FC3\u52D5\u5716\u5206\u70BA\u8F15\u5FAE\u3001\u4E2D\u5EA6\uFF0C\u53CA\u91CD\u5EA6\u7B49\u7D1A\u5225\u3002 \u4E3B\u52D5\u8108\u74E3\u72F9\u7A84\u5728\u5DF2\u958B\u767C\u570B\u5BB6\u662F\u6700\u5E38\u898B\u7684\uFF0C\u7D04\u5F71\u97FF65\u6B72\u4EE5\u4E0A\u4EBA\u53E3\u4E2D\u76842%\u3002\u57282014\u5E74\uFF0C\u5927\u90E8\u5206\u958B\u767C\u4E2D\u570B\u5BB6\u7684\u76DB\u884C\u7387\u4ECD\u4E0D\u5F97\u800C\u77E5\u3002\u5C0D\u6709\u75C7\u72C0\u537B\u6C92\u6709\u52D5\u624B\u8853\u7684\u75C5\u4EBA\uFF0C5\u5E74\u5167\u7684\u6B7B\u4EA1\u7387\u5927\u7D04\u70BA50%\uFF0C10\u5E74\u5167\u70BA90%\u3002\u4E3B\u52D5\u8108\u74E3\u72F9\u7A84\u6700\u65E9\u57281663\u5E74\u7531\u6CD5\u570B\u91AB\u751FLazare Rivi\u00E8re\u6240\u63CF\u8FF0\u3002"@zh . "157"^^ . . "\u0421\u0442\u0435\u043D\u043E\u0437 \u0430\u043E\u0440\u0442\u0430\u043B\u044C\u043D\u043E\u0433\u043E \u043A\u043B\u0430\u043F\u0430\u043D\u0430"@ru . . . . . . . "I06.0"@en . . . . . . . . . "March 2022"@en . . . . . . "Zw\u0119\u017Cenie zastawki aortalnej (stenoza/zw\u0119\u017Cenie zastawki aorty, zw\u0119\u017Cenie lewego uj\u015Bcia t\u0119tniczego, \u0142ac. stenosis ostii arteriosi sinistri, stenosis ostii aortae, ang. aortic stenosis, AS) \u2013 wada serca polegaj\u0105ca na zmniejszeniu powierzchni uj\u015Bcia aortalnego w stopniu utrudniaj\u0105cym wyp\u0142yw krwi z lewej komory do aorty. Jest trzeci\u0105 pod wzgl\u0119dem cz\u0119sto\u015Bci chorob\u0105 serca w krajach rozwini\u0119tych, po nadci\u015Bnieniu t\u0119tniczym i chorobie niedokrwiennej serca. Rozpoznanie opiera si\u0119 na obrazie echokardiograficznym. Leczenie jest operacyjne; jako pierwszy walwuloplastyk\u0119 zastawki aortalnej wykona\u0142 w 1982 roku ."@pl . . "L'estenosi a\u00F2rtica \u00E9s una valvulopatia que consisteix en una estenosi (estrenyiment) de la v\u00E0lvula a\u00F2rtica. T\u00E9 major incid\u00E8ncia en homes."@ca . . . "I35.0"@en . . . . "2"^^ . . . "Die Aortenklappenstenose, meistens verk\u00FCrzt Aortenstenose genannt, ist eine angeborene oder erworbene Einengung des Ausflusstraktes der linken Herzkammer und geh\u00F6rt zu den h\u00E4ufigsten prim\u00E4ren Herzklappenerkrankungen. Man unterscheidet: Die erste transaortale Sprengung einer Aortenstenose f\u00FChrte 1950 Charles P. Bailey durch. Zwei Jahre sp\u00E4ter wurde von ihm erstmals der transventrikul\u00E4re Zugang zur instrumentellen Sprengung einer valvul\u00E4ren Aortenstenose angewendet."@de . "844" . "\u0421\u0442\u0435\u043D\u043E\u0437 \u0430\u043E\u0440\u0442\u0430\u043B\u044C\u043D\u043E\u0433\u043E \u043A\u043B\u0430\u043F\u0430\u043D\u0430 (\u0441\u0438\u043D\u043E\u043D\u0456\u043C: \u0441\u0442\u0435\u043D\u043E\u0437 \u0433\u0438\u0440\u043B\u0430 \u0430\u043E\u0440\u0442\u0438) \u2014 \u0437\u0432\u0443\u0436\u0435\u043D\u043D\u044F \u043E\u0442\u0432\u043E\u0440\u0443 \u0430\u043E\u0440\u0442\u0430\u043B\u044C\u043D\u043E\u0433\u043E \u043A\u043B\u0430\u043F\u0430\u043D\u0430, \u0449\u043E \u043F\u0435\u0440\u0435\u0448\u043A\u043E\u0434\u0436\u0430\u0454 \u043D\u043E\u0440\u043C\u0430\u043B\u044C\u043D\u043E\u043C\u0443 \u0442\u043E\u043A\u0443 \u043A\u0440\u043E\u0432\u0456 \u0437 \u043B\u0456\u0432\u043E\u0433\u043E \u0448\u043B\u0443\u043D\u043E\u0447\u043A\u0430 \u0432 \u0430\u043E\u0440\u0442\u0443."@uk . "\u5927\u52D5\u8108\u5F01\u72ED\u7A84\u75C7"@ja . . . "\u4E3B\u52D5\u8108\u74E3\u72F9\u7A84\uFF08Aortic stenosis\uFF0C\u7C21\u7A31AS\u6216AoS\uFF09\u4E43\u63CF\u8FF0\u5DE6\u5FC3\u5BA4\u901A\u5411\u4E3B\u52D5\u8108\u7684\u74E3\u819C\u53E3\u72F9\u7A84\u7684\u73FE\u8C61\u3002\u53EF\u80FD\u662F\u7531\u4E3B\u52D5\u8108\u74E3\u7684\u7D50\u69CB\u7570\u5E38\u9020\u6210\uFF0C\u6216\u4E3B\u52D5\u8108\u74E3\u7684\u4E0A\u6E38\u6216\u4E0B\u6E38\u89E3\u5256\u7D50\u69CB\u7684\u7570\u5E38\u9020\u6210\u3002\u4E00\u822C\u4F86\u8AAA\uFF0C\u5176\u75C5\u60C5\u6703\u96A8\u6642\u9593\u6108\u767C\u52A0\u91CD\u3002\u4E00\u958B\u59CB\uFF0C\u60A3\u8005\u53EF\u80FD\u6703\u767C\u73FE\u5176\u904B\u52D5\u80FD\u529B\u6E1B\u9000\u3002\u5F8C\u96A8\u75C5\u60C5\u9032\u4E00\u6B65\u767C\u5C55\uFF0C\u53EF\u80FD\u51FA\u73FE\u5FC3\u81DF\u8870\u7AED\u3001\u660F\u53A5\u3001\u5FC3\u7D5E\u75DB\u7B49\u81E8\u5E8A\u75C7\u72C0\u8207\u9AD4\u5FB5\u3002\u660F\u53A5\u5E38\u767C\u751F\u65BC\u60A3\u8005\u7AD9\u7ACB\u6216\u904B\u52D5\u6642\uFF0C\u5FC3\u81DF\u8870\u7AED\u7684\u81E8\u5E8A\u9AD4\u5FB5\u5305\u62EC\u547C\u5438\u56F0\u96E3\uFF08\u7279\u5225\u662F\u5728\u5E73\u81E5\u3001\u591C\u665A\u6216\u904B\u52D5\u6642\uFF09\uFF0C\u4EE5\u53CA\u5916\u9031\u6027\u6C34\u816B\u3002\u4E3B\u52D5\u8108\u74E3\u819C\u8B8A\u539A\u4F46\u74E3\u819C\u53E3\u672A\u8B8A\u72F9\u7A84\u5247\u7A31\u70BA\u4E3B\u52D5\u8108\u74E3\u786C\u5316\u3002 \u81F4\u75C5\u539F\u56E0\u5305\u542B\u5148\u5929\u6027\u548C\u98A8\u6FD5\u71B1\u3002\u96D9\u8449\u6027\u52D5\u8108\u74E3\u7684\u76DB\u884C\u7387\u7D04\u70BA1-2%\uFF0C\u800C\u98A8\u6FD5\u71B1\u5247\u5927\u591A\u5F71\u97FF\u958B\u767C\u4E2D\u570B\u5BB6\u7684\u4EBA\u6C11\u3002\u5148\u5929\u6B63\u5E38\u7684\u74E3\u819C\u4E5F\u53EF\u80FD\u56E0\u5F8C\u5929\u6027\u56E0\u7D20\u786C\u5316\u3002\u98A8\u96AA\u56E0\u5B50\u8207\u51A0\u72C0\u52D5\u8108\u75BE\u75C5\u985E\u4F3C\uFF0C\u5305\u542B\u5438\u83F8\u3001\u9AD8\u8840\u58D3\u3001\u81BD\u56FA\u9187\u904E\u9AD8\uFF0C\u4EE5\u53CA\u7CD6\u5C3F\u75C5\u7B49\u3002\u6B64\u5916\uFF0C\u7537\u6027\u7F79\u60A3\u6B64\u75BE\u75C5\u7684\u98A8\u96AA\u8F03\u9AD8\u3002\u4E3B\u52D5\u8108\u74E3\u901A\u5E38\u6709\u4E09\u7247\uFF0C\u4F4D\u65BC\u5FC3\u5BA4\u53CA\u4E3B\u52D5\u8108\u4E4B\u9593\u3002\u4E3B\u52D5\u8108\u74E3\u72F9\u7A84\u6703\u7522\u751F\u5FC3\u96DC\u97F3\uFF0C\u53EF\u6839\u64DA\u8D85\u8072\u5FC3\u52D5\u5716\u5206\u70BA\u8F15\u5FAE\u3001\u4E2D\u5EA6\uFF0C\u53CA\u91CD\u5EA6\u7B49\u7D1A\u5225\u3002 \u4E3B\u52D5\u8108\u74E3\u72F9\u7A84\u7684\u75C7\u72C0\u53EF\u7528\u8D85\u8072\u6CE2\u8FFD\u8E64\u3002\u7576\u75C5\u60C5\u56B4\u91CD\u6642\uFF0C\u5176\u6CBB\u7642\u4E3B\u8981\u63A1\u7528\uFF0C\u82E5\u75C5\u4EBA\u96E3\u4EE5\u627F\u53D7\u958B\u653E\u624B\u8853\u98A8\u96AA\uFF0C\u5247\u4E00\u822C\u63A1\u7528\u7D93\u76AE\u4E3B\u52D5\u8108\u74E3\u7F6E\u63DB\u8853\uFF08TAVR\uFF09\u3002\u76EE\u524D\u5E02\u9762\u4E0A\u7684\u4EBA\u5DE5\u74E3\u819C\u4E3B\u8981\u6709\u8207\u5169\u7A2E\uFF0C\u5169\u7A2E\u5404\u6709\u5176\u512A\u7F3A\u9EDE\u3002\u53E6\u4E00\u500B\u4FB5\u5165\u6027\u8F03\u5C0F\u7684\u8853\u5F0F\u2014\u2014\uFF08BAV\uFF09\u53EA\u80FD\u5728\u5E7E\u500B\u6708\u4E4B\u5167\u5C0D\u75C5\u4EBA\u6709\u4E00\u5B9A\u76CA\u8655\u3002\u624B\u8853\u4F75\u767C\u75C7\u4E4B\u4E00\u2014\u2014\u5FC3\u81DF\u8870\u7AED\u53EF\u6309\u5176\u4ED6\u60A3\u6709\u8F15\u5EA6\u81F3\u4E2D\u5EA6\u4E3B\u52D5\u8108\u74E3\u72F9\u7A84\u7684\u60A3\u8005\u7684\u65B9\u6848\u6CBB\u7642\u3002\u75C5\u60C5\u56B4\u91CD\u60A3\u8005\u9700\u907F\u514D\u670D\u7528\u8840\u7BA1\u5F35\u529B\u7D20I\u578B\u8F49\u5316\u9176\u6291\u5236\u5291\u3001\u785D\u9178\u7518\u6CB9\u4EE5\u53CA\u4E00\u4E9B\u03B2\u53D7\u4F53\u963B\u65AD\u836F\u3002\u4F9D\u7167\u60A3\u8005\u8840\u58D3\u3001\u785D\u666E\u9209\u53CA\u53EF\u7528\u65BC\u540C\u6642\u60A3\u6709\u7684\u60A3\u8005\u3002 \u4E3B\u52D5\u8108\u74E3\u72F9\u7A84\u5728\u5DF2\u958B\u767C\u570B\u5BB6\u662F\u6700\u5E38\u898B\u7684\uFF0C\u7D04\u5F71\u97FF65\u6B72\u4EE5\u4E0A\u4EBA\u53E3\u4E2D\u76842%\u3002\u57282014\u5E74\uFF0C\u5927\u90E8\u5206\u958B\u767C\u4E2D\u570B\u5BB6\u7684\u76DB\u884C\u7387\u4ECD\u4E0D\u5F97\u800C\u77E5\u3002\u5C0D\u6709\u75C7\u72C0\u537B\u6C92\u6709\u52D5\u624B\u8853\u7684\u75C5\u4EBA\uFF0C5\u5E74\u5167\u7684\u6B7B\u4EA1\u7387\u5927\u7D04\u70BA50%\uFF0C10\u5E74\u5167\u70BA90%\u3002\u4E3B\u52D5\u8108\u74E3\u72F9\u7A84\u6700\u65E9\u57281663\u5E74\u7531\u6CD5\u570B\u91AB\u751FLazare Rivi\u00E8re\u6240\u63CF\u8FF0\u3002"@zh . . . "I06.0" . ""@en . . . . . . . . . "Gradual"@en . . . . . . . . . . . "\u062A\u0636\u064A\u0642 \u0627\u0644\u0635\u0645\u0627\u0645 \u0627\u0644\u0623\u0628\u0647\u0631\u064A \u0647\u0648 \u062A\u0636\u064A\u0642 \u064A\u0635\u064A\u0628 \u0627\u0644\u0635\u0645\u0627\u0645 \u0627\u0644\u0642\u0644\u0628\u064A \u0639\u0646\u062F \u0645\u062E\u0631\u062C \u0627\u0644\u0628\u0637\u064A\u0646 \u0627\u0644\u0623\u064A\u0633\u0631 \u0625\u0644\u0649 \u0627\u0644\u0634\u0631\u064A\u0627\u0646 \u0627\u0644\u0623\u0628\u0647\u0631\u064A\u060C \u0648\u0627\u0644\u0630\u064A \u0645\u0646\u0647 \u064A\u0645\u0631 \u0627\u0644\u062F\u0645 \u0625\u0644\u0649 \u0643\u0627\u0641\u0629 \u0623\u0646\u062D\u0627\u0621 \u0627\u0644\u062C\u0633\u0645. \u0647\u0630\u0627 \u0627\u0644\u062A\u0636\u064A\u0642 \u064A\u062A\u0633\u0628\u0628 \u0641\u064A \u0632\u064A\u0627\u062F\u0629 \u0627\u0644\u0639\u0646\u0627\u0621 \u0644\u0639\u0636\u0644\u0629 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u062A\u064A \u062A\u062D\u0627\u0648\u0644 \u062A\u0633\u064A\u064A\u0631 \u0627\u0644\u062F\u0645 \u0644\u0644\u062C\u0633\u0645 \u0645\u0646 \u062E\u0644\u0627\u0644 \u0627\u0644\u0635\u0645\u0627\u0645 \u0627\u0644\u0645\u062A\u0636\u064A\u0642. \u0647\u0630\u0627 \u064A\u0624\u062F\u064A \u0644\u0627\u0631\u062A\u0641\u0627\u0639 \u0627\u0644\u0636\u063A\u0637 \u0641\u064A \u0627\u0644\u0628\u0637\u064A\u0646 \u0627\u0644\u0623\u064A\u0633\u0631 \u0645\u0645\u0627 \u064A\u0624\u062F\u064A \u0625\u0644\u0649 \u062A\u0636\u062E\u0645\u0647\u060C \u0648\u062A\u0642\u062F\u0645 \u0627\u0644\u0645\u0631\u0636 \u064A\u0645\u0643\u0646 \u0623\u0646 \u064A\u0624\u062F\u064A - \u0628\u062F\u0648\u0646 \u0639\u0644\u0627\u062C - \u0644\u0644\u0648\u0641\u0627\u0629. \u064A\u062A\u0645\u062B\u0644 \u0627\u0644\u0639\u0644\u0627\u062C \u0628\u0625\u062C\u0631\u0627\u0621 \u0639\u0645\u0644\u064A\u0629 \u0627\u0633\u062A\u0628\u062F\u0627\u0644 \u0644\u0644\u0635\u0645\u0627\u0645 \u0627\u0644\u0623\u0628\u0647\u0631\u064A."@ar . . . . . "Aortic stenosis (AS or AoS) is the narrowing of the exit of the left ventricle of the heart (where the aorta begins), such that problems result. It may occur at the aortic valve as well as above and below this level. It typically gets worse over time. Symptoms often come on gradually with a decreased ability to exercise often occurring first. If heart failure, loss of consciousness, or heart related chest pain occur due to AS the outcomes are worse. Loss of consciousness typically occurs with standing or exercising. Signs of heart failure include shortness of breath especially when lying down, at night, or with exercise, and swelling of the legs. Thickening of the valve without narrowing is known as aortic sclerosis."@en . . . . "I35.0" . . . . "med"@en . . "Aortic stenosis"@en . . . . . "Estenosis a\u00F3rtica"@es . . . . . . . "In the center an aortic valve with severe stenosis due to rheumatic heart disease. The valve is surrounded by the aorta. The pulmonary trunk is at the lower right. The right coronary artery, cut lengthwise, is at the lower left. The left main coronary artery, also cut lengthwise, is on the right."@en . . "\u5927\u52D5\u8108\u5F01\u72ED\u7A84\u75C7\uFF08\u3060\u3044\u3069\u3046\u307F\u3083\u304F\u3079\u3093\u304D\u3087\u3046\u3055\u304F\u3057\u3087\u3046\u3001\u82F1Aortic valve stenosis\uFF1AAS\uFF09\u306F\u3001\u5927\u52D5\u8108\u5F01\u53E3\u306E\u72ED\u7A84\u306B\u3088\u3063\u3066\u5168\u8EAB\u306B\u8840\u6DB2\u304C\u9001\u308A\u51FA\u3055\u308C\u306B\u304F\u304F\u306A\u308B\u75BE\u60A3\u3067\u3042\u308B\u3002"@ja . "\u062A\u0636\u064A\u0642 \u0627\u0644\u0635\u0645\u0627\u0645 \u0627\u0644\u0623\u0628\u0647\u0631\u064A"@ar . "Aorta-balbularen estenosia, baita estenosi aortikoa ere, balbulopatia bat da, bihotzeko balbula aortikoaren zuloaren estutze anormala ezaugarri duena. Balbula-zuloaren murrizketa hori sortzetikoa edo hartutakoa izan daiteke, normalean sukar erreumatikoaren edo kaltzifikazioaren bigarren mailako ondorioa. Balbula aortikoak odol-fluxuaren norabidea kontrolatzen du ezkerreko bentrikulutik aortara."@eu . "Estenose a\u00F3rtica (EAo), tamb\u00E9m chamada estenose de v\u00E1lvula a\u00F3rtica ou estenose valvar a\u00F3rtica, \u00E9 uma doen\u00E7a de curso progressivo caracterizada pela obstru\u00E7\u00E3o \u00E0 passagem do fluxo sangu\u00EDneo da via de sa\u00EDda do ventr\u00EDculo esquerdo do cora\u00E7\u00E3o pela calcifica\u00E7\u00E3o das estruturas valvares, associada ou n\u00E3o \u00E0 fus\u00E3o das v\u00E1lvulas da valva a\u00F3rtica. Os sintomas s\u00E3o graduais e por vezes insidiosos, mas muitos indiv\u00EDduos com quadro grave de estenose podem ser assintom\u00E1ticos. Assim, os sinais cl\u00EDnicos de insufici\u00EAncia card\u00EDaca (dispneia ou ortopneia e edema de membros inferiores), perda de consci\u00EAncia (em p\u00E9 ou em exerc\u00EDcio) ou dores no peito, decorrentes do processo de calcifica\u00E7\u00E3o valvar, costumam surgir normalmente ap\u00F3s os 60 anos de idade. O espessamento da valva sem estreitamento de sua luz \u00E9 conhecido como esclerose a\u00F3rtica. A estenose a\u00F3rtica pode ser cong\u00EAnita ou adquirida. No primeiro caso, que afeta cerca de 2% da popula\u00E7\u00E3o, est\u00E3o os indiv\u00EDduos que nasceram com valva a\u00F3rtica bic\u00FAspide. No segundo caso, enquadram-se aqueles que desenvolveram a cardiopatia em virtude da febre reum\u00E1tica e os portadores da forma degenerativa da doen\u00E7a. As les\u00F5es de etiologia reum\u00E1tica s\u00E3o t\u00EDpicas de pa\u00EDses em desenvolvimento. Uma valva normal, no entanto, tamb\u00E9m pode enrijecer ao longo do tempo. Os fatores de risco s\u00E3o semelhantes aos da doen\u00E7a arterial coronariana e incluem tabagismo, hipertens\u00E3o arterial, n\u00EDveis elevados de colesterol, o diabetes e indiv\u00EDduos do sexo masculino. A valva a\u00F3rtica normal \u00E9 tric\u00FAspide e est\u00E1 localizada entre o ventr\u00EDculo esquerdo do cora\u00E7\u00E3o e a aorta. A estenose a\u00F3rtica geralmente causa sopro card\u00EDaco e pode ser classificada, com base em achados ecocardiogr\u00E1ficos, em leve, moderada, severa e grave. O diagn\u00F3stico da estenose a\u00F3rtica baseia-se na anamnese, exame f\u00EDsico e exames complementares. Desses, a ecocardiografia \u00E9 o teste de escolha para confirma\u00E7\u00E3o do diagn\u00F3stico e estabelece a severidade da estenose, detecta complica\u00E7\u00F5es e determina o tratamento mais apropriado. Se classificada como grave, o tratamento preconizado \u00E9 o cir\u00FArgico. Nos pacientes com risco cir\u00FArgico alto, os m\u00E9todos menos invasivos s\u00E3o a melhor escolha, como o implante percut\u00E2neo de valva a\u00F3rtica ou a valvoplastia mitral percut\u00E2nea por bal\u00E3o. Complica\u00E7\u00F5es, como a insufici\u00EAncia card\u00EDaca, podem ser tratadas conforme os protocolos estabelecidos nos casos classificados como estenose leve a moderada. Nos pacientes com doen\u00E7a grave, h\u00E1 uma s\u00E9rie de medicamentos a ser evitada, como os inibidores da enzima conversora de angiotensina (IECAs), nitroglicerina e alguns betabloqueadores. Dependendo da press\u00E3o arterial, o nitroprussiato ou a fenilefrina podem ser utilizados por pessoas com insufici\u00EAncia card\u00EDaca descompensada. A estenose a\u00F3rtica \u00E9 a mais comum das doen\u00E7as valvares card\u00EDacas. Ela afeta cerca de 2% das pessoas com mais de 65 anos de idade. Em pacientes sintom\u00E1ticos sem tratamento, as chances de \u00F3bito em cinco anos \u00E9 de cerca de 50% e aos 10 anos \u00E9 de cerca de 90%. A doen\u00E7a foi descrita pela primeira vez pelo m\u00E9dico franc\u00EAs Lazare Rivi\u00E8re, em 1663."@pt . . . . . "," . . . . . . . . . . "Aorta-balbularen estenosia, baita estenosi aortikoa ere, balbulopatia bat da, bihotzeko balbula aortikoaren zuloaren estutze anormala ezaugarri duena. Balbula-zuloaren murrizketa hori sortzetikoa edo hartutakoa izan daiteke, normalean sukar erreumatikoaren edo kaltzifikazioaren bigarren mailako ondorioa. Balbula aortikoak odol-fluxuaren norabidea kontrolatzen du ezkerreko bentrikulutik aortara."@eu . . . . "La estenosis de la v\u00E1lvula a\u00F3rtica o estenosis a\u00F3rtica (EA o AS, por sus siglas en ingl\u00E9s: Aortic Stenosis) es una valvulopat\u00EDa (cardiopat\u00EDa valvular) caracterizada por el estrechamiento anormal del orificio de la v\u00E1lvula a\u00F3rtica del coraz\u00F3n. Esta reducci\u00F3n del orificio valvular puede ser cong\u00E9nito o adquirida, generalmente secundaria a la fiebre reum\u00E1tica o calcificaci\u00F3n. La v\u00E1lvula a\u00F3rtica controla la direcci\u00F3n del flujo sangu\u00EDneo desde el ventr\u00EDculo izquierdo hacia la aorta. En su buen funcionamiento, la v\u00E1lvula no impide el flujo de sangre entre esos dos espacios, pero en ciertas circunstancias, la v\u00E1lvula se vuelve m\u00E1s estrecha de lo normal, dificultando el flujo sangu\u00EDneo y generando un importante gradiente de presi\u00F3n entre el ventr\u00EDculo izquierdo y la aorta."@es . . "746.3"^^ . . "Stenosis aorta"@in . . . "Aortastenose"@nl . . "Aorta stenozo estas streti\u011Do de la elflua malfermo de la maldekstra ventriklo. Kutime \u0109i tiu estas ka\u016Dzita de malordo de la aorta valvo. En tiu aorta stenozo estas streti\u011Do de la aorta valvo, kiu tiamaniere ne povas sufi\u0109e malfermi\u011Di. \u0108e aorta stenozo povas ekesti premgradiento super la valvo. La maldekstra ventriklo devas tiel generi pli altan premon por akiri \u011Din. Sango eventuale \u015Dprucas en la aorton pro troa premo."@eo . . "Aortic stenosis (AS or AoS) is the narrowing of the exit of the left ventricle of the heart (where the aorta begins), such that problems result. It may occur at the aortic valve as well as above and below this level. It typically gets worse over time. Symptoms often come on gradually with a decreased ability to exercise often occurring first. If heart failure, loss of consciousness, or heart related chest pain occur due to AS the outcomes are worse. Loss of consciousness typically occurs with standing or exercising. Signs of heart failure include shortness of breath especially when lying down, at night, or with exercise, and swelling of the legs. Thickening of the valve without narrowing is known as aortic sclerosis. Causes include being born with a bicuspid aortic valve, and rheumatic fever; a normal valve may also harden over the decades. A bicuspid aortic valve affects about one to two percent of the population. As of 2014 rheumatic heart disease mostly occurs in the developing world. Risk factors are similar to those of coronary artery disease and include smoking, high blood pressure, high cholesterol, diabetes, and being male. The aortic valve usually has three leaflets and is located between the left ventricle of the heart, and the aorta. AS typically results in a heart murmur. Its severity can be divided into mild, moderate, severe, and very severe, distinguishable by ultrasound scan of the heart. Aortic stenosis is typically followed using repeated ultrasound scans. Once it has become severe, treatment primarily involves valve replacement surgery, with transcatheter aortic valve replacement (TAVR) being an option in some who are at high risk from surgery. Valves may either be mechanical or bioprosthetic, with each having risks and benefits. Another less invasive procedure, balloon aortic valvuloplasty (BAV), may result in benefit, but for only a few months. Complications such as heart failure may be treated in the same way as in those with mild to moderate AS. In those with severe disease a number of medications should be avoided, including ACE inhibitors, nitroglycerin, and some beta blockers. Nitroprusside or phenylephrine may be used in those with decompensated heart failure depending on the blood pressure. Aortic stenosis is the most common valvular heart disease in the developed world. It affects about 2% of people who are over 65 years of age. Estimated rates were not known in most of the developing world as of 2014. In those who have symptoms, without repair the chance of death at five years is about 50% and at 10 years is about 90%. Aortic stenosis was first described by French physician Lazare Rivi\u00E8re in 1663."@en . . "157"@en . "Per stenosi aortica si indica un restringimento dell'anulus aortico, molto diffuso soprattutto in soggetti con difetti valvolari. Nelle persone apparentemente sane, ovvero senza sintomi, il rischio \u00E8 maggiore dopo i 60 anni di et\u00E0, con la naturale modifica che interviene con l'invecchiamento. Questo restringimento determina un gradiente pressorio che impone al ventricolo sinistro di sviluppare una maggiore pressione con la sistole al fine di mantenere una gittata cardiaca adeguata alle richieste metaboliche. Il miocardio nel corso degli anni e man mano che la stenosi si fa pi\u00F9 grave, sviluppa un'ipertrofia concentrica come meccanismo di compenso."@it . "Q23.0" . . . . . . "\u4E3B\u52D5\u8108\u74E3\u72F9\u7A84"@zh . . . . . "," . . . . . "396.0" . . . "Per stenosi aortica si indica un restringimento dell'anulus aortico, molto diffuso soprattutto in soggetti con difetti valvolari. Nelle persone apparentemente sane, ovvero senza sintomi, il rischio \u00E8 maggiore dopo i 60 anni di et\u00E0, con la naturale modifica che interviene con l'invecchiamento. Questo restringimento determina un gradiente pressorio che impone al ventricolo sinistro di sviluppare una maggiore pressione con la sistole al fine di mantenere una gittata cardiaca adeguata alle richieste metaboliche. Il miocardio nel corso degli anni e man mano che la stenosi si fa pi\u00F9 grave, sviluppa un'ipertrofia concentrica come meccanismo di compenso."@it . . . . "Aorta-balbularen estenosi"@eu . "Aorta stenozo"@eo . . . "178"^^ . . . "000178" . . . . "Aortastenos"@sv . "Aortastenose is een vernauwing van de uitstroomopening van de linkerhartkamer. Meestal wordt dit veroorzaakt door een aandoening aan de aortaklep. Bij deze aortaklepstenose is er een stenose (vernauwing) van de aortaklep, die daardoor niet wijd genoeg open kan. Bij een aortastenose kan een drukgradi\u00EBnt over de klep ontstaan. De linkerventrikel moet daardoor hogere drukken genereren om bloed in de aorta te krijgen. Er ontstaat op den duur linkerventrikelhypertrofie door drukbelasting."@nl . . . . . . . . . . . . . . . ","@en . . "Aorta stenozo estas streti\u011Do de la elflua malfermo de la maldekstra ventriklo. Kutime \u0109i tiu estas ka\u016Dzita de malordo de la aorta valvo. En tiu aorta stenozo estas streti\u011Do de la aorta valvo, kiu tiamaniere ne povas sufi\u0109e malfermi\u011Di. \u0108e aorta stenozo povas ekesti premgradiento super la valvo. La maldekstra ventriklo devas tiel generi pli altan premon por akiri \u011Din. Sango eventuale \u015Dprucas en la aorton pro troa premo."@eo . "396"^^ . . "Die Aortenklappenstenose, meistens verk\u00FCrzt Aortenstenose genannt, ist eine angeborene oder erworbene Einengung des Ausflusstraktes der linken Herzkammer und geh\u00F6rt zu den h\u00E4ufigsten prim\u00E4ren Herzklappenerkrankungen. Man unterscheidet: \n* die angeborene Aortenstenose (subvalvul\u00E4r, valvul\u00E4r oder supravalvul\u00E4r) \n* die durch Entz\u00FCndungen (Endokarditis), Fehlbildungen oder degenerative Prozesse erworbene Aortenklappenstenose \n* die angeborene hypertrophe Kardiomyopathie mit dynamischer Obstruktion (sog. HOCM \u2013 hypertroph-obstruktive Kardiomyopathie), die sich im Kinder-, Jugend- oder Erwachsenenalter manifestieren kann Angina Pectoris, Synkope und Dyspnoe sind bei Aortenstenose wichtige Leitsymptome, die vor allem bei Belastung und bei einer \u00D6ffnungsfl\u00E4che der Aortenklappe von unter 0,8 cm\u00B2 auftreten k\u00F6nnen. Ein Anstieg der Herzfrequenz f\u00FChrt zu einem Abfall des Schlagvolumens, aber tendenziell zu einer Zunahme des Herzzeitvolumens. Weitere Symptome sind eine blasse Gesichtsfarbe und ein niedriger Blutdruck mit verkleinerter Amplitude (Pulsdruck). Bei der Auskultation des Brustkorbs \u00FCber dem Herzen ist ein meist lautes (bei der Phonokardiographie auch \u201Espindelf\u00F6rmiges\u201C) systolisches Ger\u00E4usch, das nach dem h\u00E4ufig abgeschw\u00E4chten 1. und vor dem meist ebenfalls abgeschw\u00E4chten 2. Herzton auftritt, bis \u00FCber der Aortenregion bis zu den Karotiden fortgeleitet wahrzunehmen. \u00D6fter ist auch ein 4. Ton als Extraton zu h\u00F6ren. Die erste transaortale Sprengung einer Aortenstenose f\u00FChrte 1950 Charles P. Bailey durch. Zwei Jahre sp\u00E4ter wurde von ihm erstmals der transventrikul\u00E4re Zugang zur instrumentellen Sprengung einer valvul\u00E4ren Aortenstenose angewendet."@de . "notwithstanding exactly what?"@en . . . "395"^^ . . "395.0" . . "Q23.0"@en . . . . . "Aort\u00E1ln\u00ED sten\u00F3za (AS), jinak t\u00E9\u017E sten\u00F3za aort\u00E1ln\u00ED chlopn\u011B (z\u00FA\u017Een\u00ED aort\u00E1ln\u00ED chlopn\u011B), je srde\u010Dn\u00ED vada, p\u0159i kter\u00E9 doch\u00E1z\u00ED ke z\u00FA\u017Een\u00ED aort\u00E1ln\u00ED chlopn\u011B a t\u00EDm p\u00E1dem vzniku p\u0159ek\u00E1\u017Eky p\u0159i odvodu krve z lev\u00E9 srde\u010Dn\u00ED komory. N\u00E1sledkem toho doch\u00E1z\u00ED k tlakov\u00E9mu p\u0159et\u00ED\u017Een\u00ED t\u00E9to komory a jej\u00EDmu postupn\u00E9mu zbytn\u011Bn\u00ED."@cs . . "746.3" . . . . . . "med"@en . . . . . "\u0410\u043E\u0440\u0442\u0430\u0301\u043B\u044C\u043D\u044B\u0439 \u0441\u0442\u0435\u043D\u043E\u0301\u0437 (\u0441\u0438\u043D\u043E\u043D\u0438\u043C: \u0441\u0442\u0435\u043D\u043E\u0437 \u0443\u0441\u0442\u044C\u044F \u0430\u043E\u0440\u0442\u044B) \u2014 \u0441\u0443\u0436\u0435\u043D\u0438\u0435 \u043E\u0442\u0432\u0435\u0440\u0441\u0442\u0438\u044F \u0430\u043E\u0440\u0442\u044B \u0437\u0430 \u0441\u0447\u0451\u0442 \u0441\u0440\u0430\u0449\u0438\u0432\u0430\u043D\u0438\u044F \u0441\u0442\u0432\u043E\u0440\u043E\u043A \u0435\u0451 \u043A\u043B\u0430\u043F\u0430\u043D\u0430, \u043F\u0440\u0435\u043F\u044F\u0442\u0441\u0442\u0432\u0443\u044E\u0449\u0435\u0435 \u043D\u043E\u0440\u043C\u0430\u043B\u044C\u043D\u043E\u043C\u0443 \u0442\u043E\u043A\u0443 \u043A\u0440\u043E\u0432\u0438 \u0438\u0437 \u043B\u0435\u0432\u043E\u0433\u043E \u0436\u0435\u043B\u0443\u0434\u043E\u0447\u043A\u0430 \u0432 \u0430\u043E\u0440\u0442\u0443."@ru . "54707"^^ . . . . . "844"^^ . . "Estenose a\u00F3rtica"@pt . "Decreased ability to exercise, loss of consciousness, shortness of breath, heart related chest pain, leg swelling"@en . "Aortenklappenstenose"@de . . . . . "St\u00E9nose aortique"@fr . . . . . . . "Five-year survival ~50% without treatment in symptomatic patients"@en . . . . . . . . "Aort\u00E1ln\u00ED sten\u00F3za (AS), jinak t\u00E9\u017E sten\u00F3za aort\u00E1ln\u00ED chlopn\u011B (z\u00FA\u017Een\u00ED aort\u00E1ln\u00ED chlopn\u011B), je srde\u010Dn\u00ED vada, p\u0159i kter\u00E9 doch\u00E1z\u00ED ke z\u00FA\u017Een\u00ED aort\u00E1ln\u00ED chlopn\u011B a t\u00EDm p\u00E1dem vzniku p\u0159ek\u00E1\u017Eky p\u0159i odvodu krve z lev\u00E9 srde\u010Dn\u00ED komory. N\u00E1sledkem toho doch\u00E1z\u00ED k tlakov\u00E9mu p\u0159et\u00ED\u017Een\u00ED t\u00E9to komory a jej\u00EDmu postupn\u00E9mu zbytn\u011Bn\u00ED. Aort\u00E1ln\u00ED sten\u00F3za m\u016F\u017Ee b\u00FDt vrozen\u00E1 nebo z\u00EDskan\u00E1 (minim\u00E1ln\u011B 10 %; m\u016F\u017Ee j\u00EDt nap\u0159\u00EDklad o revmatickou hore\u010Dku). Mezi p\u0159\u00EDznaky aort\u00E1ln\u00ED sten\u00F3zy pat\u0159\u00ED , bolest na hrudi, bu\u0161en\u00ED srdce, \u010Dast\u00E1 \u00FAnava \u010Di ka\u0161el. U l\u00E9\u010Dby z\u00E1vis\u00ED na z\u00E1va\u017Enosti AS, m\u016F\u017Ee b\u00FDt chirurgick\u00E1 a doch\u00E1z\u00ED p\u0159i n\u00ED k v\u00FDm\u011Bn\u011B aort\u00E1ln\u00ED chlopn\u011B. Ve vysp\u011Bl\u00FDch st\u00E1tech sv\u011Bta pat\u0159\u00ED AS mezi nej\u010Dast\u011Bji operovan\u00E9 srde\u010Dn\u00ED vady."@cs . . . "1109557679"^^ . . . "194278"^^ . . "Estenose a\u00F3rtica (EAo), tamb\u00E9m chamada estenose de v\u00E1lvula a\u00F3rtica ou estenose valvar a\u00F3rtica, \u00E9 uma doen\u00E7a de curso progressivo caracterizada pela obstru\u00E7\u00E3o \u00E0 passagem do fluxo sangu\u00EDneo da via de sa\u00EDda do ventr\u00EDculo esquerdo do cora\u00E7\u00E3o pela calcifica\u00E7\u00E3o das estruturas valvares, associada ou n\u00E3o \u00E0 fus\u00E3o das v\u00E1lvulas da valva a\u00F3rtica. Os sintomas s\u00E3o graduais e por vezes insidiosos, mas muitos indiv\u00EDduos com quadro grave de estenose podem ser assintom\u00E1ticos. Assim, os sinais cl\u00EDnicos de insufici\u00EAncia card\u00EDaca (dispneia ou ortopneia e edema de membros inferiores), perda de consci\u00EAncia (em p\u00E9 ou em exerc\u00EDcio) ou dores no peito, decorrentes do processo de calcifica\u00E7\u00E3o valvar, costumam surgir normalmente ap\u00F3s os 60 anos de idade. O espessamento da valva sem estreitamento de sua luz \u00E9 conhecido"@pt . . . . . . "\u0410\u043E\u0440\u0442\u0430\u0301\u043B\u044C\u043D\u044B\u0439 \u0441\u0442\u0435\u043D\u043E\u0301\u0437 (\u0441\u0438\u043D\u043E\u043D\u0438\u043C: \u0441\u0442\u0435\u043D\u043E\u0437 \u0443\u0441\u0442\u044C\u044F \u0430\u043E\u0440\u0442\u044B) \u2014 \u0441\u0443\u0436\u0435\u043D\u0438\u0435 \u043E\u0442\u0432\u0435\u0440\u0441\u0442\u0438\u044F \u0430\u043E\u0440\u0442\u044B \u0437\u0430 \u0441\u0447\u0451\u0442 \u0441\u0440\u0430\u0449\u0438\u0432\u0430\u043D\u0438\u044F \u0441\u0442\u0432\u043E\u0440\u043E\u043A \u0435\u0451 \u043A\u043B\u0430\u043F\u0430\u043D\u0430, \u043F\u0440\u0435\u043F\u044F\u0442\u0441\u0442\u0432\u0443\u044E\u0449\u0435\u0435 \u043D\u043E\u0440\u043C\u0430\u043B\u044C\u043D\u043E\u043C\u0443 \u0442\u043E\u043A\u0443 \u043A\u0440\u043E\u0432\u0438 \u0438\u0437 \u043B\u0435\u0432\u043E\u0433\u043E \u0436\u0435\u043B\u0443\u0434\u043E\u0447\u043A\u0430 \u0432 \u0430\u043E\u0440\u0442\u0443."@ru . . . . . "Zw\u0119\u017Cenie zastawki aortalnej"@pl . . . . . . . . . . . . "Estenosi a\u00F2rtica"@ca . . "Zw\u0119\u017Cenie zastawki aortalnej (stenoza/zw\u0119\u017Cenie zastawki aorty, zw\u0119\u017Cenie lewego uj\u015Bcia t\u0119tniczego, \u0142ac. stenosis ostii arteriosi sinistri, stenosis ostii aortae, ang. aortic stenosis, AS) \u2013 wada serca polegaj\u0105ca na zmniejszeniu powierzchni uj\u015Bcia aortalnego w stopniu utrudniaj\u0105cym wyp\u0142yw krwi z lewej komory do aorty. Jest trzeci\u0105 pod wzgl\u0119dem cz\u0119sto\u015Bci chorob\u0105 serca w krajach rozwini\u0119tych, po nadci\u015Bnieniu t\u0119tniczym i chorobie niedokrwiennej serca. Rozpoznanie opiera si\u0119 na obrazie echokardiograficznym. Leczenie jest operacyjne; jako pierwszy walwuloplastyk\u0119 zastawki aortalnej wykona\u0142 w 1982 roku ."@pl . "Aortastenos eller aortaklaffsstenos inneb\u00E4r en f\u00F6rtr\u00E4ngning av utfl\u00F6det fr\u00E5n v\u00E4nster hj\u00E4rtkammare (f\u00F6rbi aortaklaffen) till den grad att det orsakar olika problem. Prevalensen \u00E4r 0,2 % 50-60 \u00E5ringar men kring 10 % hos personer \u00F6ver 80 \u00E5r . Aortastenos kan uppst\u00E5 i niv\u00E5 med aortaklaffen, men kan \u00E4ven bero p\u00E5 f\u00F6rtr\u00E4ngning \u00F6ver eller under denna niv\u00E5. Vanligen f\u00F6rv\u00E4rras stenosen \u00F6ver tid. Symptom uppkommer ofta successivt med en minskad f\u00F6rm\u00E5ga till anstr\u00E4ngning som vanligaste debutsymptom. Om hj\u00E4rtsvikt, medvetandef\u00F6rlust, eller k\u00E4rlkramp uppst\u00E5r \u00E4r det tecken p\u00E5 en allvarligare sjukdomsgrad. Svimning eller medvetandef\u00F6rlust intr\u00E4ffar vanligen d\u00E5 personen st\u00E4llt sig upp eller vid motion. Symptom p\u00E5 hj\u00E4rtsvikt kan vara andn\u00F6d som \u00E4r s\u00E4rskilt uttalad d\u00E5 man ligger ner, p\u00E5 natten, eller som upp"@sv . . . . . "Aortic stenosis"@en . "La estenosis de la v\u00E1lvula a\u00F3rtica o estenosis a\u00F3rtica (EA o AS, por sus siglas en ingl\u00E9s: Aortic Stenosis) es una valvulopat\u00EDa (cardiopat\u00EDa valvular) caracterizada por el estrechamiento anormal del orificio de la v\u00E1lvula a\u00F3rtica del coraz\u00F3n. Esta reducci\u00F3n del orificio valvular puede ser cong\u00E9nito o adquirida, generalmente secundaria a la fiebre reum\u00E1tica o calcificaci\u00F3n. La v\u00E1lvula a\u00F3rtica controla la direcci\u00F3n del flujo sangu\u00EDneo desde el ventr\u00EDculo izquierdo hacia la aorta. En su buen funcionamiento, la v\u00E1lvula no impide el flujo de sangre entre esos dos espacios, pero en ciertas circunstancias, la v\u00E1lvula se vuelve m\u00E1s estrecha de lo normal, dificultando el flujo sangu\u00EDneo y generando un importante gradiente de presi\u00F3n entre el ventr\u00EDculo izquierdo y la aorta."@es . . . 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"Aort\u00E1ln\u00ED sten\u00F3za"@cs . . "L'estenosi a\u00F2rtica \u00E9s una valvulopatia que consisteix en una estenosi (estrenyiment) de la v\u00E0lvula a\u00F2rtica. T\u00E9 major incid\u00E8ncia en homes."@ca . . . . . . . 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