. . "Anandamide"@nl . "\u0410\u043D\u0430\u043D\u0434\u0430\u043C\u0438\u0434"@ru . "Arachidonylethanolamid, auch Anandamid genannt, ist das Ethanolamin-Derivat der Arachidons\u00E4ure, einer vierfach unges\u00E4ttigten Fetts\u00E4ure, die besonders h\u00E4ufig im zentralen Nervensystem vorkommt. Anandamid wird vom K\u00F6rper selbst gebildet (sofern Linols\u00E4ure vorliegt) und ist somit eine endogene Substanz."@de . . . . . "changed"@en . . "Anandamide is een neurotransmitter. Het speelt een rol bij pijn, depressie, geheugen, vruchtbaarheid en het hongergevoel. De stof wordt in het lichaam afgebroken door hydrolase. De naam anandamide is afgeleid van het woord ananda dat in het Sanskriet 'geluk' of 'gelukzaligheid' betekent. Anandamide is belangrijk in hersendelen die te maken hebben met het geheugen, hogere denkprocessen en controle over de motoriek."@nl . . . . . "Anandamid"@cs . . . . . "\u0410\u043D\u0430\u043D\u0434\u0430\u043C\u0456\u0434 (\u0435\u0442\u0430\u043D\u043E\u043B\u0430\u043C\u0456\u0434 \u0430\u0440\u0430\u0445\u0456\u0434\u043E\u043D\u043E\u0432\u043E\u0457 \u043A\u0438\u0441\u043B\u043E\u0442\u0438) \u2014 \u0435\u043D\u0434\u043E\u0433\u0435\u043D\u043D\u0438\u0439 \u043B\u0456\u0433\u0430\u043D\u0434 \u043A\u0430\u043D\u0430\u0431\u0456\u043D\u043E\u0457\u0434\u043D\u0438\u0445 \u0440\u0435\u0446\u0435\u043F\u0442\u043E\u0440\u0456\u0432, \u0431\u0456\u043E\u043B\u043E\u0433\u0456\u0447\u043D\u043E \u0430\u043A\u0442\u0438\u0432\u043D\u0430 \u0440\u0435\u0447\u043E\u0432\u0438\u043D\u0430, \u044F\u043A\u0430 \u0443\u0442\u0432\u043E\u0440\u044E\u0454\u0442\u044C\u0441\u044F \u0432 \u043E\u0440\u0433\u0430\u043D\u0456\u0437\u043C\u0456 \u043B\u044E\u0434\u0438\u043D\u0438 \u0442\u0430 \u0442\u0432\u0430\u0440\u0438\u043D; \u0435\u043D\u0434\u043E\u043A\u0430\u043D\u0430\u0431\u0456\u043D\u043E\u0457\u0434\u043D\u0438\u0439 \u043D\u0435\u0439\u0440\u043E\u0442\u0440\u0430\u043D\u0441\u043C\u0456\u0442\u0435\u0440."@uk . . . . . "Anandamide"@en . . "Anandamide (ANA), also known as N-arachidonoylethanolamine (AEA), is a fatty acid neurotransmitter. Anandamide was the first endocannabinoid to be discovered: it participates in the body's endocannabinoid system by binding to cannabinoid receptors, the same receptors that the psychoactive compound THC in cannabis acts on. Anandamide is found in nearly all tissues in a wide range of animals. Anandamide has also been found in plants, including small amounts in chocolate. The name 'anandamide' is taken from the Sanskrit word ananda, which means \"joy, bliss, delight\", plus amide. Anandamide is derived from the non-oxidative metabolism of arachidonic acid, an essential omega-6 fatty acid. It is synthesized from N-arachidonoyl phosphatidylethanolamine by multiple pathways. It is degraded primarily by the fatty acid amide hydrolase (FAAH) enzyme, which converts anandamide into ethanolamine and arachidonic acid. As such, inhibitors of FAAH lead to elevated anandamide levels and are being pursued for therapeutic use."@en . . "Anandamid"@pl . . . . . . . "L\u2019anandamide ou N-arachidonoylethanolamide ou AEA, est un neurotransmetteur cannabino\u00EFde endog\u00E8ne pr\u00E9sent dans l'organisme des animaux comme des humains, en particulier dans le cerveau. Il est aussi pr\u00E9sent en faible quantit\u00E9 dans le cacao. Son nom est la contraction du sanskrit ananda, qui signifie \u00AB b\u00E9atitude \u00BB et amide, sa fonction chimique. Elle est synth\u00E9tis\u00E9e \u00E0 partir du N-arachidonoyl phosphatidyl\u00E9thanolamine par de nombreuses voies m\u00E9taboliques. Elle est d\u00E9grad\u00E9e essentiellement par l'enzyme Fatty Acid Amide Hydrolase (FAAH), qui convertit l'anandamide en \u00E9thanolamine et en acide arachidonique. Ainsi, les inhibiteurs de la FAAH entra\u00EEnent une augmentation des niveaux d'anandamide et sont utilis\u00E9s pour un usage th\u00E9rapeutique."@fr . . . . . "Anandamide"@fr . . "464364547"^^ . . . . . . . "Anandamide"@it . "Anandamide is een neurotransmitter. Het speelt een rol bij pijn, depressie, geheugen, vruchtbaarheid en het hongergevoel. De stof wordt in het lichaam afgebroken door hydrolase. De naam anandamide is afgeleid van het woord ananda dat in het Sanskriet 'geluk' of 'gelukzaligheid' betekent. Anandamide is belangrijk in hersendelen die te maken hebben met het geheugen, hogere denkprocessen en controle over de motoriek."@nl . . "\u82B1\u751F\u56DB\u70EF\u4E59\u9187\u80FA\uFF0C\u4EA6\u7A31N-\u82B1\u751F\u56DB\u70EF\u4E59\u9187\u80FA\u6216AEA\uFF0C\u662F\u4E00\u7A2E\u5167\u6E90\u6027\u7684\u5927\u9EBB\u9187\u985E\u795E\u7D93\u50B3\u5C0E\u7269\u8CEA\u3002\u6B64\u547D\u540D\u53D6\u81EA\u68B5\u6587\uFF08\u548C\u5370\u5EA6\u534A\u5CF6\u5B97\u6559\u7528\u8A9E\uFF09\u7684\u300C\u963F\u96E3\u9640\uFF08ananda\uFF09\u300D\uFF0C\u610F\u4E3A\u300C\u559C\u6085\u3001\u6975\u6A02\u3001\u6B23\u559C\u300D\uFF0C\u4EE5\u53CA\u91AF\u80FA\u3002\u5B83\u662F\u7531N-\u82B1\u751F\u56DB\u70EF\u9170\u78F7\u8102\u9170\u4E59\u9187\u80FA\u900F\u904E\u591A\u7A2E\u9014\u5F91\u5408\u6210\u3002\u82B1\u751F\u56DB\u70EF\u4E59\u9187\u80FA\uFF0C\u4E3B\u8981\u662F\u7531(FAAH)\u5C07\u5176\u964D\u89E3\u6210\u4E59\u9187\u80FA\u548C\u82B1\u751F\u56DB\u70EF\u9178\u3002\u5982\u6B64\uFF0C(FAAH)\u7684\u6291\u5236\u7269\u5C0E\u81F4\u82B1\u751F\u56DB\u70EF\u4E59\u9187\u80FA\u5C64\u7D1A\u7684\u63D0\u5347\uFF0C\u4E26\u88AB\u7528\u4E8E\u6CBB\u7642\u3002"@zh . . . "N-arachidonoylethanolamine"@en . . . . . . . . . . . . "\u30A2\u30CA\u30F3\u30C0\u30DF\u30C9 (anandamide) \u307E\u305F\u306F\u30A2\u30CA\u30F3\u30C0\u30DE\u30A4\u30C9\u306F\u3001\u30A2\u30E9\u30AD\u30C9\u30CE\u30A4\u30EB\u30A8\u30BF\u30CE\u30FC\u30EB\u30A2\u30DF\u30C9 (arachidonoylethanolamide, AEA) \u3068\u3082\u547C\u3070\u308C\u308B\u3001\u795E\u7D4C\u4F1D\u9054\u7269\u8CEA\u3042\u308B\u3044\u306F\u8102\u8CEA\u30E1\u30C7\u30A3\u30A8\u30FC\u30BF\u30FC\u306E\u4E00\u7A2E\u3067\u3001\u5185\u56E0\u6027\u306E\u30AB\u30F3\u30CA\u30D3\u30CE\u30A4\u30C9\u53D7\u5BB9\u4F53\u30EA\u30AC\u30F3\u30C9\uFF08\u5185\u56E0\u6027\u30AB\u30F3\u30CA\u30D3\u30CE\u30A4\u30C9\uFF09\u3068\u3057\u3066\u6700\u521D\u306B\u767A\u898B\u3055\u308C\u305F\u7269\u8CEA\u3067\u3042\u308B\u3002\u52D5\u7269\u4F53\u5185\u306B\u3042\u308A\u3001\u7279\u306B\u8133\u306B\u591A\u3044\u3002\u5FEB\u611F\u306A\u3069\u306B\u95A2\u4FC2\u3059\u308B\u8133\u5185\u9EBB\u85AC\u7269\u8CEA\u306E\u4E00\u3064\u3068\u3082\u8003\u3048\u3089\u308C\u308B\u304C\u3001\u4E2D\u67A2\u795E\u7D4C\u7CFB\u304A\u3088\u3073\u672B\u68A2\u3067\u591A\u69D8\u306A\u6A5F\u80FD\u3092\u6301\u3063\u3066\u3044\u308B\u3002\u69CB\u9020\u7684\u306B\u306F\u30A2\u30E9\u30AD\u30C9\u30F3\u9178\u306B\u7531\u6765\u3059\u308B\u30A8\u30A4\u30B3\u30B5\u30CE\u30A4\u30C9\u306E\u4E00\u7A2E\u3067\u3042\u308B\u3002\u307E\u305FN-\u30A2\u30B7\u30EB\u30A8\u30BF\u30CE\u30FC\u30EB\u30A2\u30DF\u30F3\u3068\u898B\u308B\u3053\u3068\u3082\u3067\u304D\u308B\u3002 1992\u5E74\u3001\u30D8\u30D6\u30E9\u30A4\u5927\u5B66\u306ERaphael Mechoulam\u306E\u7814\u7A76\u5BA4\u306B\u304A\u3044\u3066\u3001\u30C1\u30A7\u30B3\u306E\u5206\u6790\u5316\u5B66\u8005Lum\u00EDr Ond\u0159ej Hanu\u0161\u3068\u30A2\u30E1\u30EA\u30AB\u306E\u5206\u5B50\u85AC\u7406\u5B66\u8005William Anthony Devane\u306B\u3088\u3063\u3066\u5206\u96E2\u30FB\u69CB\u9020\u6C7A\u5B9A\u304C\u884C\u308F\u308C\u3001\u547D\u540D\u3055\u308C\u305F\u3002\u30A2\u30CA\u30F3\u30C0\u30DF\u30C9\u3068\u306F\u3001\u30B5\u30F3\u30B9\u30AF\u30EA\u30C3\u30C8\u306E\u30A2\u30FC\u30CA\u30F3\u30C0\uFF08\u6CD5\u60A6\u3001\u6B53\u559C\u306E\u610F\uFF09\u3068\u30A2\u30DF\u30C9\u3092\u5408\u308F\u305B\u305F\u9020\u8A9E\u3067\u3042\u308B\u3002"@ja . . . . "L'anandamide, o arachidonoiletanolammide (AEA), fa parte di una nuova classe di mediatori lipidici, ad azione prevalentemente autocrina e paracrina, collettivamente noti come endocannabinoidi.L'AEA \u00E8 un neuro-modulatore che mima gli effetti dei composti psicoattivi presenti nella cannabis, noti come cannabinoidi. Questo composto, il cui nome deriva dal sanscrito \"\u0101nanda\", beatitudine interiore, \u00E8 stato isolato e caratterizzato dal chimico ceco Lum\u00EDr Ond\u0159ej Hanu\u0161 e dal farmacologo americano nel laboratorio di Raphael Mechoulam dell'Universit\u00E0 di Gerusalemme nel 1992. L'anandamide \u00E8 principalmente prodotta a partire dal fosfolipide (NarPE), per mezzo di una via metabolica in cui entrano in gioco gli enzimi N-aciltransferasi e fosfodiesterasi NAPE-PLD (N-Arachidonil-fosfatidiletanolamina fosfolipasi di tipo D).L'inattivazione invece \u00E8 promossa da un'idrolisi catalizzata dall'enzima (Amide Idrolasi degli Acidi Grassi) con conseguente formazione di acido arachidonico ed etanolammina. La sua localizzazione nel SNC \u00E8 a livello della membrana postsinaptica e se liberata lega i recettori presinaptici CB1 agendo quindi in maniera retrograda.La sua presenza \u00E8 stata inoltre osservata nel plasma suggerendo anche un suo ruolo di tipo ormonale."@it . . "Anandamid, \u00E4ven kallad arakidonyletanolamin, \u00E4r en endokannabinoid som uppt\u00E4cktes av \u00E5r 1992. Namnet kommer fr\u00E5n ananda (sanskrit f\u00F6r \"lycksalighet\") och amid. Man fann f\u00F6rst att \u03949-tetrahydrocannabinol, vilken \u00E4r en av de psykoaktiva cannabinoider man finner i cannabis, dockar i vad man b\u00F6rjade kalla cannabinoidreceptorer i hj\u00E4rnan. Man b\u00F6rjade d\u00E5 s\u00F6ka efter den kroppsegna substans som normalt dockar i dem. Cannabidiol utvinns vanligtvis fr\u00E5n hampa och saknar de psykoaktiva egenskaperna som har. Senare forskning har visat att intag av CBD-olja p\u00E5visat en \u00F6kad koncentration av anandamid i kroppen genom att bromsa \u00E5terupptaget och nedbrytningen av substansen. Anandamid syntetiseras, likt arakidonsyra och kv\u00E4veoxid, vid behov till skillnad fr\u00E5n \"vanliga\" signalsubstanser som l\u00E4ggs p\u00E5 lagring. Anandamid bryts ner genom hydrolys. \u00C4mnets effekter kan antingen vara centrala, i hj\u00E4rna och ryggm\u00E4rg, eller perifera, i andra delar av kroppen. Anandamid och liknande \u00E4mnen finner man \u00E4ven i mycket sm\u00E5 kvantiteter i kakaob\u00F6nan och i choklad. Anandamid p\u00E5verkar bland annat v\u00E5rt generella sinnestillst\u00E5nd och har kopplingar till flera neuroaktiva system i hj\u00E4rnan som reglerar bl.a. uts\u00F6ndring/\u00E5terupptag av serotonin och dopamin, signalsubstanser som p\u00E5verkar v\u00E5rt psykiska m\u00E5ende och kognitiva funktioner. Studier har visat att patienter med depression, \u00E5ngest-problematik, ADD/ADHD och liknande tillst\u00E5nd uppvisar l\u00E4gre niv\u00E5er av anandamid \u00E4n m\u00E4nniskor utan dessa tillst\u00E5nd. Det p\u00E5g\u00E5r intensiv forskning runt om i v\u00E4rlden f\u00F6r att b\u00E4ttre f\u00F6rst\u00E5 hur anandamid reglerar/p\u00E5verkar v\u00E5r h\u00E4lsa samt hur olika tillskott i sin tur p\u00E5verkar kroppens uts\u00F6ndring/\u00E5terupptag av \u00E4mnet. Anandamid spelar en viktigt roll i reglering av matvanor samt neural reglering av motivation och v\u00E4lbehag."@sv . . . . "104526"^^ . "Anandamida"@es . . "Anandamida o araquidonoiletanolamida o (abreviadamente) AEA,\u200B compuesto qu\u00EDmico org\u00E1nico que forma parte de una misma clase de mediadores lip\u00EDdicos de acci\u00F3n prevalentemente y colectivamente conocidos como endocanabinoides. Los compuestos psicoactivos presentes en la cannabis, llamados canabinoides, imitan los efectos del neurotransmisor AEA. Este compuesto, cuyo nombre deriva, por la sensaci\u00F3n que produce, de la palabra s\u00E1nscrita \"ananda\" (beatitud interior o portador de paz y felicidad interna) y la palabra usada en qu\u00EDmica amida, fue aislado y descubierto por el qu\u00EDmico checo y el farmac\u00E9utico estadounidense en el laboratorio de Raphael Mechoulam en la Universidad de Jerusal\u00E9n en 1992. La f\u00F3rmula qu\u00EDmica de la anandamida es: C22H37NO2. La masa molar es 347,53 g/mol El n\u00FAmero CAS: 94421\u201368\u20138"@es . . . "Anandamid"@de . . "Anandamida o araquidonoiletanolamida o (abreviadamente) AEA,\u200B compuesto qu\u00EDmico org\u00E1nico que forma parte de una misma clase de mediadores lip\u00EDdicos de acci\u00F3n prevalentemente y colectivamente conocidos como endocanabinoides. Los compuestos psicoactivos presentes en la cannabis, llamados canabinoides, imitan los efectos del neurotransmisor AEA. La f\u00F3rmula qu\u00EDmica de la anandamida es: C22H37NO2. La masa molar es 347,53 g/mol El n\u00FAmero CAS: 94421\u201368\u20138"@es . . . . . . . . . . "Anandamida, tamb\u00E9m conhecida como N-araquidonoiletanolamina (AEA), \u00E9 um \u00E1cido graxo que atua como neurotransmissor derivado do metabolismo n\u00E3o oxidativo do \u00E1cido araquid\u00F4nico, um \u00E1cido graxo essencial da fam\u00EDlia dos \u00F4mega 6. O nome \u00E9 uma jun\u00E7\u00E3o dos termos ananda (que em s\u00E2nscrito significa \"alegria\", \"felicidade\") e amida. \u00C9 sintetizada a partir do N-araquidonoilfosfatidiletanolamina atrav\u00E9s de m\u00FAltiplas vias metab\u00F3licas. \u00C9 hidrolisada pela enzima FAAH (amida hidrolase de \u00E1cidos graxos), sendo convertida em etanolamina e \u00E1cido araquid\u00F4nico. Assim sendo, inibidores da FAAH levam \u00E0 eleva\u00E7\u00E3o dos n\u00EDveis de anandamida e est\u00E3o sendo pesquisados para fins terap\u00EAuticos."@pt . . "arachidonoylethanolamide"@en . . . . . . "1112942407"^^ . . . . "Anandamid"@sv . "\u30A2\u30CA\u30F3\u30C0\u30DF\u30C9 (anandamide) \u307E\u305F\u306F\u30A2\u30CA\u30F3\u30C0\u30DE\u30A4\u30C9\u306F\u3001\u30A2\u30E9\u30AD\u30C9\u30CE\u30A4\u30EB\u30A8\u30BF\u30CE\u30FC\u30EB\u30A2\u30DF\u30C9 (arachidonoylethanolamide, AEA) \u3068\u3082\u547C\u3070\u308C\u308B\u3001\u795E\u7D4C\u4F1D\u9054\u7269\u8CEA\u3042\u308B\u3044\u306F\u8102\u8CEA\u30E1\u30C7\u30A3\u30A8\u30FC\u30BF\u30FC\u306E\u4E00\u7A2E\u3067\u3001\u5185\u56E0\u6027\u306E\u30AB\u30F3\u30CA\u30D3\u30CE\u30A4\u30C9\u53D7\u5BB9\u4F53\u30EA\u30AC\u30F3\u30C9\uFF08\u5185\u56E0\u6027\u30AB\u30F3\u30CA\u30D3\u30CE\u30A4\u30C9\uFF09\u3068\u3057\u3066\u6700\u521D\u306B\u767A\u898B\u3055\u308C\u305F\u7269\u8CEA\u3067\u3042\u308B\u3002\u52D5\u7269\u4F53\u5185\u306B\u3042\u308A\u3001\u7279\u306B\u8133\u306B\u591A\u3044\u3002\u5FEB\u611F\u306A\u3069\u306B\u95A2\u4FC2\u3059\u308B\u8133\u5185\u9EBB\u85AC\u7269\u8CEA\u306E\u4E00\u3064\u3068\u3082\u8003\u3048\u3089\u308C\u308B\u304C\u3001\u4E2D\u67A2\u795E\u7D4C\u7CFB\u304A\u3088\u3073\u672B\u68A2\u3067\u591A\u69D8\u306A\u6A5F\u80FD\u3092\u6301\u3063\u3066\u3044\u308B\u3002\u69CB\u9020\u7684\u306B\u306F\u30A2\u30E9\u30AD\u30C9\u30F3\u9178\u306B\u7531\u6765\u3059\u308B\u30A8\u30A4\u30B3\u30B5\u30CE\u30A4\u30C9\u306E\u4E00\u7A2E\u3067\u3042\u308B\u3002\u307E\u305FN-\u30A2\u30B7\u30EB\u30A8\u30BF\u30CE\u30FC\u30EB\u30A2\u30DF\u30F3\u3068\u898B\u308B\u3053\u3068\u3082\u3067\u304D\u308B\u3002 1992\u5E74\u3001\u30D8\u30D6\u30E9\u30A4\u5927\u5B66\u306ERaphael Mechoulam\u306E\u7814\u7A76\u5BA4\u306B\u304A\u3044\u3066\u3001\u30C1\u30A7\u30B3\u306E\u5206\u6790\u5316\u5B66\u8005Lum\u00EDr Ond\u0159ej Hanu\u0161\u3068\u30A2\u30E1\u30EA\u30AB\u306E\u5206\u5B50\u85AC\u7406\u5B66\u8005William Anthony Devane\u306B\u3088\u3063\u3066\u5206\u96E2\u30FB\u69CB\u9020\u6C7A\u5B9A\u304C\u884C\u308F\u308C\u3001\u547D\u540D\u3055\u308C\u305F\u3002\u30A2\u30CA\u30F3\u30C0\u30DF\u30C9\u3068\u306F\u3001\u30B5\u30F3\u30B9\u30AF\u30EA\u30C3\u30C8\u306E\u30A2\u30FC\u30CA\u30F3\u30C0\uFF08\u6CD5\u60A6\u3001\u6B53\u559C\u306E\u610F\uFF09\u3068\u30A2\u30DF\u30C9\u3092\u5408\u308F\u305B\u305F\u9020\u8A9E\u3067\u3042\u308B\u3002"@ja . . . "\u0410\u043D\u0430\u043D\u0434\u0430\u043C\u0456\u0434 (\u0435\u0442\u0430\u043D\u043E\u043B\u0430\u043C\u0456\u0434 \u0430\u0440\u0430\u0445\u0456\u0434\u043E\u043D\u043E\u0432\u043E\u0457 \u043A\u0438\u0441\u043B\u043E\u0442\u0438) \u2014 \u0435\u043D\u0434\u043E\u0433\u0435\u043D\u043D\u0438\u0439 \u043B\u0456\u0433\u0430\u043D\u0434 \u043A\u0430\u043D\u0430\u0431\u0456\u043D\u043E\u0457\u0434\u043D\u0438\u0445 \u0440\u0435\u0446\u0435\u043F\u0442\u043E\u0440\u0456\u0432, \u0431\u0456\u043E\u043B\u043E\u0433\u0456\u0447\u043D\u043E \u0430\u043A\u0442\u0438\u0432\u043D\u0430 \u0440\u0435\u0447\u043E\u0432\u0438\u043D\u0430, \u044F\u043A\u0430 \u0443\u0442\u0432\u043E\u0440\u044E\u0454\u0442\u044C\u0441\u044F \u0432 \u043E\u0440\u0433\u0430\u043D\u0456\u0437\u043C\u0456 \u043B\u044E\u0434\u0438\u043D\u0438 \u0442\u0430 \u0442\u0432\u0430\u0440\u0438\u043D; \u0435\u043D\u0434\u043E\u043A\u0430\u043D\u0430\u0431\u0456\u043D\u043E\u0457\u0434\u043D\u0438\u0439 \u043D\u0435\u0439\u0440\u043E\u0442\u0440\u0430\u043D\u0441\u043C\u0456\u0442\u0435\u0440."@uk . . . . . "Anandamida, tamb\u00E9m conhecida como N-araquidonoiletanolamina (AEA), \u00E9 um \u00E1cido graxo que atua como neurotransmissor derivado do metabolismo n\u00E3o oxidativo do \u00E1cido araquid\u00F4nico, um \u00E1cido graxo essencial da fam\u00EDlia dos \u00F4mega 6. O nome \u00E9 uma jun\u00E7\u00E3o dos termos ananda (que em s\u00E2nscrito significa \"alegria\", \"felicidade\") e amida. \u00C9 sintetizada a partir do N-araquidonoilfosfatidiletanolamina atrav\u00E9s de m\u00FAltiplas vias metab\u00F3licas. \u00C9 hidrolisada pela enzima FAAH (amida hidrolase de \u00E1cidos graxos), sendo convertida em etanolamina e \u00E1cido araquid\u00F4nico. Assim sendo, inibidores da FAAH levam \u00E0 eleva\u00E7\u00E3o dos n\u00EDveis de anandamida e est\u00E3o sendo pesquisados para fins terap\u00EAuticos."@pt . . "Anandamid (AEA) \u2013 organiczny zwi\u0105zek chemiczny z grupy psychoaktywnych kannabinoid\u00F3w wyst\u0119puj\u0105cy w organizmach \u017Cywych. Wchodzi w sk\u0142ad uk\u0142adu endokannabinoidowego. Jest neuroprzeka\u017Anikiem wydzielaj\u0105cym si\u0119 podczas snu i relaksu. Dzia\u0142a zar\u00F3wno o\u015Brodkowo jak i obwodowo. Anandamid jest alkaloidem kakaowca. Okaza\u0142o si\u0119, \u017Ce w niskich st\u0119\u017Ceniach anandamid aktywuje enzym zwany kinaz\u0105 i w ten spos\u00F3b u\u0142atwia implantacj\u0119 zarodka w macicy. Jednak ju\u017C przy czterokrotnie wy\u017Cszym st\u0119\u017Ceniu, zamiast aktywowa\u0107 ERK, anandamid blokuje procesy prowadz\u0105ce do implantacji zarodka."@pl . . "28911"^^ . . "Arachidonylethanolamid, auch Anandamid genannt, ist das Ethanolamin-Derivat der Arachidons\u00E4ure, einer vierfach unges\u00E4ttigten Fetts\u00E4ure, die besonders h\u00E4ufig im zentralen Nervensystem vorkommt. Anandamid wird vom K\u00F6rper selbst gebildet (sofern Linols\u00E4ure vorliegt) und ist somit eine endogene Substanz."@de . "N-arachidonoylethanolamine"@en . . . . . . . . . . . . . . . . . . "Anandamida"@pt . . . . "\u0410\u043D\u0430\u043D\u0434\u0430\u043C\u0438\u0434 (\u044D\u0442\u0430\u043D\u043E\u043B\u0430\u043C\u0438\u0434 \u0430\u0440\u0430\u0445\u0438\u0434\u043E\u043D\u043E\u0432\u043E\u0439 \u043A\u0438\u0441\u043B\u043E\u0442\u044B; \u0441\u043E\u043A\u0440. \u0410\u0415\u0410) \u2014 \u043E\u0440\u0433\u0430\u043D\u0438\u0447\u0435\u0441\u043A\u043E\u0435 \u0441\u043E\u0435\u0434\u0438\u043D\u0435\u043D\u0438\u0435, \u044D\u043D\u0434\u043E\u0433\u0435\u043D\u043D\u044B\u0439 \u043A\u0430\u043D\u043D\u0430\u0431\u0438\u043D\u043E\u0438\u0434\u043D\u044B\u0439 \u043D\u0435\u0439\u0440\u043E\u0442\u0440\u0430\u043D\u0441\u043C\u0438\u0442\u0442\u0435\u0440. \u042D\u0442\u043E \u0441\u043E\u0435\u0434\u0438\u043D\u0435\u043D\u0438\u0435 \u0441\u043E\u0434\u0435\u0440\u0436\u0438\u0442\u0441\u044F \u0432\u043E \u043C\u043D\u043E\u0433\u0438\u0445 \u043E\u0440\u0433\u0430\u043D\u0430\u0445 \u0436\u0438\u0432\u043E\u0442\u043D\u044B\u0445 \u0438 \u0447\u0435\u043B\u043E\u0432\u0435\u043A\u0430. \u0421\u043E\u0435\u0434\u0438\u043D\u0435\u043D\u0438\u0435 \u0432\u043F\u0435\u0440\u0432\u044B\u0435 \u0432\u044B\u0434\u0435\u043B\u0435\u043D\u043E \u0447\u0435\u0448\u0441\u043A\u0438\u043C \u0445\u0438\u043C\u0438\u043A\u043E\u043C-\u0430\u043D\u0430\u043B\u0438\u0442\u0438\u043A\u043E\u043C \u041B\u044E\u043C\u0438\u0440\u043E\u043C \u0425\u0430\u043D\u0443\u0448\u0435\u043C (\u0447\u0435\u0448. Lum\u00EDr Ond\u0159ej Hanu\u0161) \u0438 \u0430\u043C\u0435\u0440\u0438\u043A\u0430\u043D\u0441\u043A\u0438\u043C \u043C\u043E\u043B\u0435\u043A\u0443\u043B\u044F\u0440\u043D\u044B\u043C \u0444\u0430\u0440\u043C\u0430\u043A\u043E\u043B\u043E\u0433\u043E\u043C (\u0430\u043D\u0433\u043B. William Anthony Devane) \u0432 \u043B\u0430\u0431\u043E\u0440\u0430\u0442\u043E\u0440\u0438\u0438 \u0420\u0430\u0444\u0430\u044D\u043B\u044F \u041C\u0435\u0448\u0443\u043B\u0430\u043C\u0430 \u043D\u0430 \u043A\u0430\u0444\u0435\u0434\u0440\u0435 \u0445\u0438\u043C\u0438\u0438 \u043F\u0440\u0438\u0440\u043E\u0434\u043D\u044B\u0445 \u0432\u0435\u0449\u0435\u0441\u0442\u0432 (Department of Natural Products) \u0415\u0432\u0440\u0435\u0439\u0441\u043A\u043E\u0433\u043E \u0443\u043D\u0438\u0432\u0435\u0440\u0441\u0438\u0442\u0435\u0442\u0430 \u0432 \u0418\u0435\u0440\u0443\u0441\u0430\u043B\u0438\u043C\u0435 \u0432 1992 \u0433\u043E\u0434\u0443; \u0432 \u0434\u0430\u043B\u044C\u043D\u0435\u0439\u0448\u0435\u043C \u0438\u043C\u0438 \u0436\u0435 \u0431\u044B\u043B\u0430 \u043E\u043F\u0440\u0435\u0434\u0435\u043B\u0435\u043D\u0430 \u0435\u0433\u043E \u0441\u0442\u0440\u0443\u043A\u0442\u0443\u0440\u0430."@ru . . "\u82B1\u751F\u56DB\u70EF\u4E59\u9187\u80FA"@zh . . "Anandamid (arachidonoylethanolamid; AEA) je kanabinoidn\u00ED ligand (endokanabinoid; endokanabinoidn\u00ED neurotransmiter) na kanabinoidn\u00ED receptory. Nal\u00E9z\u00E1 se v n\u011Bkter\u00FDch zv\u00ED\u0159ec\u00EDch a lidsk\u00FDch org\u00E1nech, p\u0159edev\u0161\u00EDm pak v mozku. Izoloval jej a jeho strukturu ur\u010Dil \u010Desk\u00FD analytick\u00FD chemik Lum\u00EDr Ond\u0159ej Hanu\u0161 a americk\u00FD molekul\u00E1rn\u00ED farmakolog v laborato\u0159i Raphaela Mechoulama na Hebrejsk\u00E9 Univerzit\u011B v Jeruzal\u00E9m\u011B v roce 1992. Jeho n\u00E1zev je odvozen ze sanskrtsk\u00E9ho slova ananda, co\u017E znamen\u00E1 \u201Ebla\u017Eenost\u201C \u010Di \u201Edokonal\u00E9 \u0161t\u011Bst\u00ED\u201C a slova amid, kter\u00E9 vyjad\u0159uje chemickou podstatu t\u00E9to l\u00E1tky. Je to endogenn\u00ED kanabinoid, nebo\u0165 se v mozku v\u00E1\u017Ee na receptory, na kter\u00E9 se v\u00E1\u017Ee tak\u00E9 psychotomimeticky aktivn\u00ED (\u2212)-trans-\u03949-tetrahydrokanabinol, rostlinn\u00FD kanabinoid z Cannabis sativa (ha\u0161i\u0161, marihuana). Anandamid je bu\u010F , nebo neurotransmiter. Tato ned\u00E1vno objeven\u00E1 informa\u010Dn\u00ED molekula hraje roli v bolesti, depresi, chuti k j\u00EDdlu, pam\u011Bti a plodnosti. Anandamid se vyskytuje v mal\u00FDch mno\u017Estv\u00EDch v kakaov\u00FDch bobech a v \u010Dokol\u00E1d\u011B. Dva nejhojn\u011Bj\u0161\u00ED N-acylethanolaminy nalezen\u00E9 v \u010Dokol\u00E1d\u011B ( a ) neaktivuj\u00ED kanabinoidn\u00ED receptor, ale \u00FA\u010Dinn\u011B inhibuj\u00ED rozpad anandamidu. Nazna\u010Duje to, \u017Ee tyto l\u00E1tky mohou p\u0159isp\u00EDvat k neodolateln\u00E9 touze po \u010Dokol\u00E1d\u011B t\u00EDm, \u017Ee zabra\u0148uj\u00ED rozpadu anandamidu a ten se v m\u00EDstech jeho \u00FA\u010Dinku hromad\u00ED."@cs . "\u0410\u043D\u0430\u043D\u0434\u0430\u043C\u0438\u0434 (\u044D\u0442\u0430\u043D\u043E\u043B\u0430\u043C\u0438\u0434 \u0430\u0440\u0430\u0445\u0438\u0434\u043E\u043D\u043E\u0432\u043E\u0439 \u043A\u0438\u0441\u043B\u043E\u0442\u044B; \u0441\u043E\u043A\u0440. \u0410\u0415\u0410) \u2014 \u043E\u0440\u0433\u0430\u043D\u0438\u0447\u0435\u0441\u043A\u043E\u0435 \u0441\u043E\u0435\u0434\u0438\u043D\u0435\u043D\u0438\u0435, \u044D\u043D\u0434\u043E\u0433\u0435\u043D\u043D\u044B\u0439 \u043A\u0430\u043D\u043D\u0430\u0431\u0438\u043D\u043E\u0438\u0434\u043D\u044B\u0439 \u043D\u0435\u0439\u0440\u043E\u0442\u0440\u0430\u043D\u0441\u043C\u0438\u0442\u0442\u0435\u0440. \u042D\u0442\u043E \u0441\u043E\u0435\u0434\u0438\u043D\u0435\u043D\u0438\u0435 \u0441\u043E\u0434\u0435\u0440\u0436\u0438\u0442\u0441\u044F \u0432\u043E \u043C\u043D\u043E\u0433\u0438\u0445 \u043E\u0440\u0433\u0430\u043D\u0430\u0445 \u0436\u0438\u0432\u043E\u0442\u043D\u044B\u0445 \u0438 \u0447\u0435\u043B\u043E\u0432\u0435\u043A\u0430. \u0421\u043E\u0435\u0434\u0438\u043D\u0435\u043D\u0438\u0435 \u0432\u043F\u0435\u0440\u0432\u044B\u0435 \u0432\u044B\u0434\u0435\u043B\u0435\u043D\u043E \u0447\u0435\u0448\u0441\u043A\u0438\u043C \u0445\u0438\u043C\u0438\u043A\u043E\u043C-\u0430\u043D\u0430\u043B\u0438\u0442\u0438\u043A\u043E\u043C \u041B\u044E\u043C\u0438\u0440\u043E\u043C \u0425\u0430\u043D\u0443\u0448\u0435\u043C (\u0447\u0435\u0448. Lum\u00EDr Ond\u0159ej Hanu\u0161) \u0438 \u0430\u043C\u0435\u0440\u0438\u043A\u0430\u043D\u0441\u043A\u0438\u043C \u043C\u043E\u043B\u0435\u043A\u0443\u043B\u044F\u0440\u043D\u044B\u043C \u0444\u0430\u0440\u043C\u0430\u043A\u043E\u043B\u043E\u0433\u043E\u043C (\u0430\u043D\u0433\u043B. William Anthony Devane) \u0432 \u043B\u0430\u0431\u043E\u0440\u0430\u0442\u043E\u0440\u0438\u0438 \u0420\u0430\u0444\u0430\u044D\u043B\u044F \u041C\u0435\u0448\u0443\u043B\u0430\u043C\u0430 \u043D\u0430 \u043A\u0430\u0444\u0435\u0434\u0440\u0435 \u0445\u0438\u043C\u0438\u0438 \u043F\u0440\u0438\u0440\u043E\u0434\u043D\u044B\u0445 \u0432\u0435\u0449\u0435\u0441\u0442\u0432 (Department of Natural Products) \u0415\u0432\u0440\u0435\u0439\u0441\u043A\u043E\u0433\u043E \u0443\u043D\u0438\u0432\u0435\u0440\u0441\u0438\u0442\u0435\u0442\u0430 \u0432 \u0418\u0435\u0440\u0443\u0441\u0430\u043B\u0438\u043C\u0435 \u0432 1992 \u0433\u043E\u0434\u0443; \u0432 \u0434\u0430\u043B\u044C\u043D\u0435\u0439\u0448\u0435\u043C \u0438\u043C\u0438 \u0436\u0435 \u0431\u044B\u043B\u0430 \u043E\u043F\u0440\u0435\u0434\u0435\u043B\u0435\u043D\u0430 \u0435\u0433\u043E \u0441\u0442\u0440\u0443\u043A\u0442\u0443\u0440\u0430. \u041D\u0430\u0437\u0432\u0430\u043D\u0438\u0435 \u0432\u0435\u0449\u0435\u0441\u0442\u0432\u0430 \u0432\u0437\u044F\u0442\u043E \u0438\u0437 \u0441\u0430\u043D\u0441\u043A\u0440\u0438\u0442\u0430. \u0421\u043B\u043E\u0432\u043E \u0430\u043D\u0430\u043D\u0434\u0430 (\u0441\u0430\u043D\u0441\u043A\u0440. \u0906\u0928\u0902\u0926, \u0101nanda IAST) \u043F\u0435\u0440\u0435\u0432\u043E\u0434\u0438\u0442\u0441\u044F \u043A\u0430\u043A \u00AB\u0431\u043B\u0430\u0436\u0435\u043D\u0441\u0442\u0432\u043E\u00BB \u0438\u043B\u0438 \u00AB\u0438\u0434\u0435\u0430\u043B\u044C\u043D\u043E\u0435 \u0441\u0447\u0430\u0441\u0442\u044C\u0435\u00BB, \u0430 \u0441\u043B\u043E\u0432\u043E \u0430\u043C\u0438\u0434 \u043E\u0431\u043E\u0437\u043D\u0430\u0447\u0430\u0435\u0442 \u0445\u0438\u043C\u0438\u0447\u0435\u0441\u043A\u0438\u0439 \u043A\u043B\u0430\u0441\u0441 \u0432\u0435\u0449\u0435\u0441\u0442\u0432\u0430."@ru . . . . . . . "Anandamide (ANA), also known as N-arachidonoylethanolamine (AEA), is a fatty acid neurotransmitter. Anandamide was the first endocannabinoid to be discovered: it participates in the body's endocannabinoid system by binding to cannabinoid receptors, the same receptors that the psychoactive compound THC in cannabis acts on. Anandamide is found in nearly all tissues in a wide range of animals. Anandamide has also been found in plants, including small amounts in chocolate. The name 'anandamide' is taken from the Sanskrit word ananda, which means \"joy, bliss, delight\", plus amide."@en . . . . . . . . . "Anandamid (arachidonoylethanolamid; AEA) je kanabinoidn\u00ED ligand (endokanabinoid; endokanabinoidn\u00ED neurotransmiter) na kanabinoidn\u00ED receptory. Nal\u00E9z\u00E1 se v n\u011Bkter\u00FDch zv\u00ED\u0159ec\u00EDch a lidsk\u00FDch org\u00E1nech, p\u0159edev\u0161\u00EDm pak v mozku. Izoloval jej a jeho strukturu ur\u010Dil \u010Desk\u00FD analytick\u00FD chemik Lum\u00EDr Ond\u0159ej Hanu\u0161 a americk\u00FD molekul\u00E1rn\u00ED farmakolog v laborato\u0159i Raphaela Mechoulama na Hebrejsk\u00E9 Univerzit\u011B v Jeruzal\u00E9m\u011B v roce 1992. Jeho n\u00E1zev je odvozen ze sanskrtsk\u00E9ho slova ananda, co\u017E znamen\u00E1 \u201Ebla\u017Eenost\u201C \u010Di \u201Edokonal\u00E9 \u0161t\u011Bst\u00ED\u201C a slova amid, kter\u00E9 vyjad\u0159uje chemickou podstatu t\u00E9to l\u00E1tky. Je to endogenn\u00ED kanabinoid, nebo\u0165 se v mozku v\u00E1\u017Ee na receptory, na kter\u00E9 se v\u00E1\u017Ee tak\u00E9 psychotomimeticky aktivn\u00ED (\u2212)-trans-\u03949-tetrahydrokanabinol, rostlinn\u00FD kanabinoid z Cannabis sativa (ha\u0161i\u0161, marihuana). Anandamid je bu\u010F , ne"@cs . . . . . . "\u82B1\u751F\u56DB\u70EF\u4E59\u9187\u80FA\uFF0C\u4EA6\u7A31N-\u82B1\u751F\u56DB\u70EF\u4E59\u9187\u80FA\u6216AEA\uFF0C\u662F\u4E00\u7A2E\u5167\u6E90\u6027\u7684\u5927\u9EBB\u9187\u985E\u795E\u7D93\u50B3\u5C0E\u7269\u8CEA\u3002\u6B64\u547D\u540D\u53D6\u81EA\u68B5\u6587\uFF08\u548C\u5370\u5EA6\u534A\u5CF6\u5B97\u6559\u7528\u8A9E\uFF09\u7684\u300C\u963F\u96E3\u9640\uFF08ananda\uFF09\u300D\uFF0C\u610F\u4E3A\u300C\u559C\u6085\u3001\u6975\u6A02\u3001\u6B23\u559C\u300D\uFF0C\u4EE5\u53CA\u91AF\u80FA\u3002\u5B83\u662F\u7531N-\u82B1\u751F\u56DB\u70EF\u9170\u78F7\u8102\u9170\u4E59\u9187\u80FA\u900F\u904E\u591A\u7A2E\u9014\u5F91\u5408\u6210\u3002\u82B1\u751F\u56DB\u70EF\u4E59\u9187\u80FA\uFF0C\u4E3B\u8981\u662F\u7531(FAAH)\u5C07\u5176\u964D\u89E3\u6210\u4E59\u9187\u80FA\u548C\u82B1\u751F\u56DB\u70EF\u9178\u3002\u5982\u6B64\uFF0C(FAAH)\u7684\u6291\u5236\u7269\u5C0E\u81F4\u82B1\u751F\u56DB\u70EF\u4E59\u9187\u80FA\u5C64\u7D1A\u7684\u63D0\u5347\uFF0C\u4E26\u88AB\u7528\u4E8E\u6CBB\u7642\u3002"@zh . . . . "N-\uC544\uB77C\uD0A4\uB3C4\uB178\uC77C \uC5D0\uD0C4\uC62C\uC544\uBBFC(N-arachidonoylethanolamine) \uB610\uB294 AEA\uB85C\uB3C4 \uC54C\uB824\uC9C4 \uC544\uB09C\uB2E4\uBBF8\uB4DC(Anandamide, \uC544\uB09C\uB2E4\uB9C8\uC774\uB4DC)\uB294 \uD544\uC218 \uC624\uBA54\uAC00-6 \uC9C0\uBC29\uC0B0\uC778 \uC5D0\uC774\uCF54\uC0AC\uD14C\uD2B8\uB77C\uC5D0\uB178\uC0B0(eicosatetraenoic acid \uB610\uB294 \uC544\uB77C\uD0A4\uB3C8\uC0B0)\uC758 \uBE44\uC0B0\uD654\uB300\uC0AC\uC5D0\uC11C \uC720\uB798\uB41C \uC9C0\uBC29\uC0B0 \uC2E0\uACBD\uC804\uB2EC\uBB3C\uC9C8\uC774\uB2E4."@ko . . . . "Anandamide_skeletal.svg"@en . . . . "L\u2019anandamide ou N-arachidonoylethanolamide ou AEA, est un neurotransmetteur cannabino\u00EFde endog\u00E8ne pr\u00E9sent dans l'organisme des animaux comme des humains, en particulier dans le cerveau. Il est aussi pr\u00E9sent en faible quantit\u00E9 dans le cacao. Son nom est la contraction du sanskrit ananda, qui signifie \u00AB b\u00E9atitude \u00BB et amide, sa fonction chimique. Elle est synth\u00E9tis\u00E9e \u00E0 partir du N-arachidonoyl phosphatidyl\u00E9thanolamine par de nombreuses voies m\u00E9taboliques. Elle est d\u00E9grad\u00E9e essentiellement par l'enzyme Fatty Acid Amide Hydrolase (FAAH), qui convertit l'anandamide en \u00E9thanolamine et en acide arachidonique. Ainsi, les inhibiteurs de la FAAH entra\u00EEnent une augmentation des niveaux d'anandamide et sont utilis\u00E9s pour un usage th\u00E9rapeutique."@fr . "\u0623\u0646\u0627\u0646\u062F\u0627\u0645\u064A\u062F"@ar . . . . . . . . . . . "arachidonoylethanolamide"@en . . . . "N-\uC544\uB77C\uD0A4\uB3C4\uB178\uC77C \uC5D0\uD0C4\uC62C\uC544\uBBFC(N-arachidonoylethanolamine) \uB610\uB294 AEA\uB85C\uB3C4 \uC54C\uB824\uC9C4 \uC544\uB09C\uB2E4\uBBF8\uB4DC(Anandamide, \uC544\uB09C\uB2E4\uB9C8\uC774\uB4DC)\uB294 \uD544\uC218 \uC624\uBA54\uAC00-6 \uC9C0\uBC29\uC0B0\uC778 \uC5D0\uC774\uCF54\uC0AC\uD14C\uD2B8\uB77C\uC5D0\uB178\uC0B0(eicosatetraenoic acid \uB610\uB294 \uC544\uB77C\uD0A4\uB3C8\uC0B0)\uC758 \uBE44\uC0B0\uD654\uB300\uC0AC\uC5D0\uC11C \uC720\uB798\uB41C \uC9C0\uBC29\uC0B0 \uC2E0\uACBD\uC804\uB2EC\uBB3C\uC9C8\uC774\uB2E4."@ko . . . . . . . . . . . . . . . . . . . . . . . . . "(5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-tetraenamide"@en . . . . . "L'anandamide, o arachidonoiletanolammide (AEA), fa parte di una nuova classe di mediatori lipidici, ad azione prevalentemente autocrina e paracrina, collettivamente noti come endocannabinoidi.L'AEA \u00E8 un neuro-modulatore che mima gli effetti dei composti psicoattivi presenti nella cannabis, noti come cannabinoidi. Questo composto, il cui nome deriva dal sanscrito \"\u0101nanda\", beatitudine interiore, \u00E8 stato isolato e caratterizzato dal chimico ceco Lum\u00EDr Ond\u0159ej Hanu\u0161 e dal farmacologo americano nel laboratorio di Raphael Mechoulam dell'Universit\u00E0 di Gerusalemme nel 1992."@it . . "\u0410\u043D\u0430\u043D\u0434\u0430\u043C\u0456\u0434"@uk . "\u0623\u0646\u0627\u0646\u062F\u0627\u0645\u064A\u062F (Anandamide \u0648\u064A\u0631\u0645\u0632 \u0644\u0647 AEA \u0645\u0646 N-arachidonoylethanolamine \u0646-\u0623\u0631\u0627\u0643\u064A\u062F\u0648\u0646\u064A\u0644 \u0625\u064A\u062B\u0627\u0646\u0648\u0644 \u0623\u0645\u064A\u0646) \u0647\u0648 \u0623\u062D\u062F \u0627\u0644\u0646\u0648\u0627\u0642\u0644 \u0627\u0644\u0639\u0635\u0628\u064A\u0629 \u0645\u0646 \u0641\u0635\u064A\u0644\u0629 \u0627\u0644\u0643\u0627\u0646\u0627\u0628\u064A\u0646\u0648\u064A\u062F \u0630\u0627\u062A \u0627\u0644\u0645\u0646\u0634\u0623 \u0627\u0644\u062F\u0627\u062E\u0644\u064A \u0641\u064A \u062C\u0633\u0645 \u0627\u0644\u0625\u0646\u0633\u0627\u0646\u060C \u0623\u064A \u0623\u0646 \u0627\u0644\u062C\u0633\u0645 \u064A\u0642\u0648\u0645 \u0628\u062A\u0631\u0643\u064A\u0628\u0647\u0627\u060C \u0648\u0647\u0648 \u0645\u0634\u062A\u0642 \u0645\u0646 \u062D\u0645\u0636 \u0627\u0644\u0623\u0631\u0627\u0643\u064A\u062F\u0648\u0646\u064A\u0643. \u0627\u0634\u062A\u0642 \u0627\u0644\u0627\u0633\u0645 \u0645\u0646 \u0627\u0644\u0643\u0644\u0645\u0629 \u0627\u0644\u0633\u0646\u0633\u0643\u0631\u064A\u062A\u064A\u0629 \u0100nanda \u0623\u0646\u0627\u0646\u062F\u0627 \u0648\u0627\u0644\u062A\u064A \u062A\u0639\u0646\u064A \u0627\u0644\u0633\u0639\u0627\u062F\u0629\u060C \u0645\u0639 \u0625\u0636\u0627\u0641\u0629 \u0643\u0644\u0645\u0629 \u0623\u0645\u064A\u062F \u0644\u0647\u0627."@ar . . . . . . . . . "Anandamid (AEA) \u2013 organiczny zwi\u0105zek chemiczny z grupy psychoaktywnych kannabinoid\u00F3w wyst\u0119puj\u0105cy w organizmach \u017Cywych. Wchodzi w sk\u0142ad uk\u0142adu endokannabinoidowego. Jest neuroprzeka\u017Anikiem wydzielaj\u0105cym si\u0119 podczas snu i relaksu. Dzia\u0142a zar\u00F3wno o\u015Brodkowo jak i obwodowo. Anandamid jest alkaloidem kakaowca. Zwi\u0105zek ten sprzyja \u2013 w niskich st\u0119\u017Ceniach \u2013 podtrzymaniu ci\u0105\u017Cy, natomiast w wysokich powoduje poronienia \u2013 zaobserwowali badacze z USA. Do takich wniosk\u00F3w doszli naukowcy z zespo\u0142u Sudhansu Dey z Vanderbilt University Medical Center w Nashville, kt\u00F3rzy prowadzili badania nad rol\u0105 anandamidu na proces zagnie\u017Cd\u017Cania (tzw. implantacji) zarodk\u00F3w mysich w macicy. Anandamid oddzia\u0142uje te\u017C na receptory CB1 znajduj\u0105ce si\u0119 na kom\u00F3rkach zarodka. Naukowcy obserwowali ju\u017C wcze\u015Bniej, \u017Ce jego produkcja ro\u015Bnie w organizmie samic tu\u017C przed implantacj\u0105 zarodka i spada w czasie tego procesu. Nie potrafili jednak oceni\u0107 wp\u0142ywu anandamidu na przebieg samej implantacji. Okaza\u0142o si\u0119, \u017Ce w niskich st\u0119\u017Ceniach anandamid aktywuje enzym zwany kinaz\u0105 i w ten spos\u00F3b u\u0142atwia implantacj\u0119 zarodka w macicy. Jednak ju\u017C przy czterokrotnie wy\u017Cszym st\u0119\u017Ceniu, zamiast aktywowa\u0107 ERK, anandamid blokuje procesy prowadz\u0105ce do implantacji zarodka. Badania opublikowane w 2003 roku wykaza\u0142y, \u017Ce u biegaczy i rowerzyst\u00F3w, kt\u00F3rzy \u0107wiczyli z umiarkowan\u0105 intensywno\u015Bci\u0105 w d\u0142ugim okresie, nast\u0119puje du\u017Cy wzrost poziomu anandamidu. Sk\u0142ania to badaczy do pogl\u0105du, \u017Ce wydzielaj\u0105cy si\u0119 podczas wysi\u0142ku anandamid mo\u017Ce wywo\u0142ywa\u0107 odurzenie kannabinoidowe i wyst\u0105pienie fenomenu euforii biegacza, objawiaj\u0105cego si\u0119 popraw\u0105 nastroju oraz zwi\u0119kszeniem wytrzyma\u0142o\u015Bci i odporno\u015Bci organizmu na b\u00F3l. Stwierdzono r\u00F3wnie\u017C, \u017Ce anandamid jest produkowany w ciele nie tylko w odpowiedzi na wysi\u0142ek fizyczny, ale r\u00F3wnie\u017C podczas technik \u201Epracy z cia\u0142em\u201D (ang. bodywork) takich jak np. masa\u017C."@pl . "Anandamid, \u00E4ven kallad arakidonyletanolamin, \u00E4r en endokannabinoid som uppt\u00E4cktes av \u00E5r 1992. Namnet kommer fr\u00E5n ananda (sanskrit f\u00F6r \"lycksalighet\") och amid. Man fann f\u00F6rst att \u03949-tetrahydrocannabinol, vilken \u00E4r en av de psykoaktiva cannabinoider man finner i cannabis, dockar i vad man b\u00F6rjade kalla cannabinoidreceptorer i hj\u00E4rnan. Man b\u00F6rjade d\u00E5 s\u00F6ka efter den kroppsegna substans som normalt dockar i dem. Cannabidiol utvinns vanligtvis fr\u00E5n hampa och saknar de psykoaktiva egenskaperna som har. Senare forskning har visat att intag av CBD-olja p\u00E5visat en \u00F6kad koncentration av anandamid i kroppen genom att bromsa \u00E5terupptaget och nedbrytningen av substansen. Anandamid syntetiseras, likt arakidonsyra och kv\u00E4veoxid, vid behov till skillnad fr\u00E5n \"vanliga\" signalsubstanser som l\u00E4ggs p\u00E5 lagri"@sv . . . . "\u30A2\u30CA\u30F3\u30C0\u30DF\u30C9"@ja . "\u0623\u0646\u0627\u0646\u062F\u0627\u0645\u064A\u062F (Anandamide \u0648\u064A\u0631\u0645\u0632 \u0644\u0647 AEA \u0645\u0646 N-arachidonoylethanolamine \u0646-\u0623\u0631\u0627\u0643\u064A\u062F\u0648\u0646\u064A\u0644 \u0625\u064A\u062B\u0627\u0646\u0648\u0644 \u0623\u0645\u064A\u0646) \u0647\u0648 \u0623\u062D\u062F \u0627\u0644\u0646\u0648\u0627\u0642\u0644 \u0627\u0644\u0639\u0635\u0628\u064A\u0629 \u0645\u0646 \u0641\u0635\u064A\u0644\u0629 \u0627\u0644\u0643\u0627\u0646\u0627\u0628\u064A\u0646\u0648\u064A\u062F \u0630\u0627\u062A \u0627\u0644\u0645\u0646\u0634\u0623 \u0627\u0644\u062F\u0627\u062E\u0644\u064A \u0641\u064A \u062C\u0633\u0645 \u0627\u0644\u0625\u0646\u0633\u0627\u0646\u060C \u0623\u064A \u0623\u0646 \u0627\u0644\u062C\u0633\u0645 \u064A\u0642\u0648\u0645 \u0628\u062A\u0631\u0643\u064A\u0628\u0647\u0627\u060C \u0648\u0647\u0648 \u0645\u0634\u062A\u0642 \u0645\u0646 \u062D\u0645\u0636 \u0627\u0644\u0623\u0631\u0627\u0643\u064A\u062F\u0648\u0646\u064A\u0643. \u0627\u0634\u062A\u0642 \u0627\u0644\u0627\u0633\u0645 \u0645\u0646 \u0627\u0644\u0643\u0644\u0645\u0629 \u0627\u0644\u0633\u0646\u0633\u0643\u0631\u064A\u062A\u064A\u0629 \u0100nanda \u0623\u0646\u0627\u0646\u062F\u0627 \u0648\u0627\u0644\u062A\u064A \u062A\u0639\u0646\u064A \u0627\u0644\u0633\u0639\u0627\u062F\u0629\u060C \u0645\u0639 \u0625\u0636\u0627\u0641\u0629 \u0643\u0644\u0645\u0629 \u0623\u0645\u064A\u062F \u0644\u0647\u0627."@ar . "\uC544\uB09C\uB2E4\uBBF8\uB4DC"@ko . . . . . . . . . . "-N-icosa-5,8,11,14-tetraenamide"@en .