"Flowering Locus C (FLC) is a MADS-box gene that in late-flowering ecotypes of the plant Arabidopsis thaliana is responsible for vernalization. In a new seedling FLC is expressed, which prevents flowering. Upon exposure to cold, less FLC is expressed (to a degree depending on the amount of cold), and flowering becomes possible. FLC is extensively regulated through epigenetic modifications and transcriptional control. The expression of FLC is affected by other genes including , and (VRN2)."@en . . . . . "Flowering Locus C"@ru . . . . . . . "1110779806"^^ . "Flowering Locus C (FLC) \u00E8 un gene MADS-box responsabile della vernalizzazione negli ecotipi a fioritura ritardata di Arabidopsis thaliana. Sul gene FLC \u00E8 possibile individuare: \n* dominio MADS (che lega il DNA) \n* dominio I (lega altri fattori formando omodimeri o eterodimeri) \n* dominio K (promuove l'interazione con altre proteine di attivazione trascrizionale) \n* dominio C-terminale L'espressione di FLC \u00E8 influenzata da altri geni tra cui , e ."@it . . . . "Flowering Locus C"@it . . . . . . "Flowering Locus C (FLC) is a MADS-box gene that in late-flowering ecotypes of the plant Arabidopsis thaliana is responsible for vernalization. In a new seedling FLC is expressed, which prevents flowering. Upon exposure to cold, less FLC is expressed (to a degree depending on the amount of cold), and flowering becomes possible. FLC is extensively regulated through epigenetic modifications and transcriptional control. The expression of FLC is affected by other genes including , and (VRN2). Wild Arabidopsis plants have different alleles for the FLC gene, which correspond to ecotypes which either (a) flower rapidly and produce a number of generations during one summer (summer-annual), or (b) flower only after vernalization (winter-annual or late-flowering). This kind of variation can also be provided by variation in the (FRI) gene."@en . . . "Flowering Locus C (FLC) \u2014 \u0433\u0435\u043D MADS-box, \u043A\u043E\u0442\u043E\u0440\u044B\u0439 \u0443 \u043F\u043E\u0437\u0434\u043D\u043E\u0446\u0432\u0435\u0442\u0443\u0449\u0438\u0445 \u044D\u043A\u043E\u0442\u0438\u043F\u043E\u0432 \u0440\u0430\u0441\u0442\u0435\u043D\u0438\u044F Arabidopsis thaliana \u043E\u0442\u0432\u0435\u0447\u0430\u0435\u0442 \u0437\u0430 \u044F\u0440\u043E\u0432\u0438\u0437\u0430\u0446\u0438\u044E. \u0413\u0435\u043D FLC \u044D\u043A\u0441\u043F\u0440\u0435\u0441\u0441\u0438\u0440\u0443\u0435\u0442\u0441\u044F \u0443 \u043C\u043E\u043B\u043E\u0434\u044B\u0445 \u0441\u0430\u0436\u0435\u043D\u0446\u0435\u0432 \u0438 \u043F\u043E\u0434\u0430\u0432\u043B\u044F\u0435\u0442 \u0438\u0445 \u0446\u0432\u0435\u0442\u0435\u043D\u0438\u0435, \u0438\u043D\u0433\u0438\u0431\u0438\u0440\u0443\u044F \u044D\u043A\u0441\u043F\u0440\u0435\u0441\u0441\u0438\u044E \u0431\u0435\u043B\u043A\u0430 FT (Flowering Locus T), \u043A\u043E\u0442\u043E\u0440\u044B\u0439 \u0438 \u0437\u0430\u043F\u0443\u0441\u043A\u0430\u0435\u0442 \u0446\u0432\u0435\u0442\u0435\u043D\u0438\u0435. \u041F\u043E\u0441\u043B\u0435 \u0432\u044B\u0434\u0435\u0440\u0436\u0438\u0432\u0430\u043D\u0438\u044F \u043D\u0430 \u0445\u043E\u043B\u043E\u0434\u0443, \u044D\u043A\u0441\u043F\u0440\u0435\u0441\u0441\u0438\u044F FLC \u0441\u043D\u0438\u0436\u0430\u0435\u0442\u0441\u044F \u043F\u0440\u043E\u043F\u043E\u0440\u0446\u0438\u043E\u043D\u0430\u043B\u044C\u043D\u043E \u043F\u043E\u043D\u0438\u0436\u0435\u043D\u0438\u044E \u0442\u0435\u043C\u043F\u0435\u0440\u0430\u0442\u0443\u0440\u044B \u0438 \u0446\u0432\u0435\u0442\u0435\u043D\u0438\u0435 \u0441\u0442\u0430\u043D\u043E\u0432\u0438\u0442\u0441\u044F \u0432\u043E\u0437\u043C\u043E\u0436\u043D\u044B\u043C. \u0412\u043E \u0432\u0440\u0435\u043C\u044F \u044F\u0440\u043E\u0432\u0438\u0437\u0430\u0446\u0438\u0438 \u0443\u0440\u043E\u0432\u0435\u043D\u044C FLC \u043F\u043E\u043D\u0438\u0436\u0430\u0435\u0442\u0441\u044F, \u0447\u0442\u043E \u0447\u0430\u0441\u0442\u0438\u0447\u043D\u043E \u0432\u044B\u0437\u0432\u0430\u043D\u043E \u0434\u0435\u0439\u0441\u0442\u0432\u0438\u0435\u043C \u0434\u0440\u0443\u0433\u043E\u0433\u043E \u0431\u0435\u043B\u043A\u0430 VIN3 (Vernalization Insensitive 3). VIN3 \u043F\u043E\u044F\u0432\u043B\u044F\u0435\u0442\u0441\u044F \u0432 \u0440\u0430\u0441\u0442\u0435\u043D\u0438\u0438 \u0442\u043E\u043B\u044C\u043A\u043E \u043F\u043E\u0441\u043B\u0435 \u0442\u043E\u0433\u043E, \u043A\u0430\u043A \u043E\u043D\u043E \u043F\u043E\u0434\u0432\u0435\u0440\u0433\u043B\u043E\u0441\u044C \u0432\u043E\u0437\u0434\u0435\u0439\u0441\u0442\u0432\u0438\u044E \u043D\u0438\u0437\u043A\u043E\u0439 \u0442\u0435\u043C\u043F\u0435\u0440\u0430\u0442\u0443\u0440\u044B, \u0438 \u043E\u043D \u043F\u043E\u0441\u0442\u0435\u043F\u0435\u043D\u043D\u043E \u0438\u0441\u0447\u0435\u0437\u0430\u0435\u0442 \u043F\u043E\u0441\u043B\u0435 \u0432\u043E\u0437\u0432\u0440\u0430\u0449\u0435\u043D\u0438\u044F \u0440\u0430\u0441\u0442\u0435\u043D\u0438\u044F \u0432 \u0431\u043E\u043B\u0435\u0435 \u0442\u0451\u043F\u043B\u044B\u0435 \u0443\u0441\u043B\u043E\u0432\u0438\u044F. \u041F\u043E\u0441\u043B\u0435 \u0438\u0441\u0447\u0435\u0437\u043D\u043E\u0432\u0435\u043D\u0438\u044F VIN3 \u0431\u0435\u043B\u043A\u0438 VRN1 (Vernalization1) \u0438 VRN2 (Vernalization2) \u043F\u043E\u0434\u0434\u0435\u0440\u0436\u0438\u0432\u0430\u044E\u0442 \u043D\u0438\u0437\u043A\u0438\u0439 \u0443\u0440"@ru . . "3498"^^ . . "Flowering Locus C"@en . "21746104"^^ . . . "Flowering Locus C (FLC) \u00E8 un gene MADS-box responsabile della vernalizzazione negli ecotipi a fioritura ritardata di Arabidopsis thaliana. Sul gene FLC \u00E8 possibile individuare: \n* dominio MADS (che lega il DNA) \n* dominio I (lega altri fattori formando omodimeri o eterodimeri) \n* dominio K (promuove l'interazione con altre proteine di attivazione trascrizionale) \n* dominio C-terminale FLC \u00E8 espresso nelle giovani piante sin dalla gametogenesi e inibisce la fioritura. Dopo aver attraversato un periodo freddo, l'espressione di FLC viene inibita e, di conseguenza, la pianta differenzia i tessuti fiorali. La regolazione di questo gene si basa prevalentemente su fenomeni epigenetici e sul controllo trascrizionale. L'espressione di FLC \u00E8 influenzata da altri geni tra cui , e . Gli ecotipi selvatici Arabidopsis hanno differenti alleli per il gene FLC, dando o piante che fioriscono rapidamente producendo pi\u00F9 generazioni durante un'estate (fioritura anticipata), o piante che fioriscono solo dopo vernalizzazione (fioritura ritardata). Variazioni di questo genere posso dipendere anche dal gene FRI, induttore di FLC."@it . . . "Flowering Locus C (FLC) \u2014 \u0433\u0435\u043D MADS-box, \u043A\u043E\u0442\u043E\u0440\u044B\u0439 \u0443 \u043F\u043E\u0437\u0434\u043D\u043E\u0446\u0432\u0435\u0442\u0443\u0449\u0438\u0445 \u044D\u043A\u043E\u0442\u0438\u043F\u043E\u0432 \u0440\u0430\u0441\u0442\u0435\u043D\u0438\u044F Arabidopsis thaliana \u043E\u0442\u0432\u0435\u0447\u0430\u0435\u0442 \u0437\u0430 \u044F\u0440\u043E\u0432\u0438\u0437\u0430\u0446\u0438\u044E. \u0413\u0435\u043D FLC \u044D\u043A\u0441\u043F\u0440\u0435\u0441\u0441\u0438\u0440\u0443\u0435\u0442\u0441\u044F \u0443 \u043C\u043E\u043B\u043E\u0434\u044B\u0445 \u0441\u0430\u0436\u0435\u043D\u0446\u0435\u0432 \u0438 \u043F\u043E\u0434\u0430\u0432\u043B\u044F\u0435\u0442 \u0438\u0445 \u0446\u0432\u0435\u0442\u0435\u043D\u0438\u0435, \u0438\u043D\u0433\u0438\u0431\u0438\u0440\u0443\u044F \u044D\u043A\u0441\u043F\u0440\u0435\u0441\u0441\u0438\u044E \u0431\u0435\u043B\u043A\u0430 FT (Flowering Locus T), \u043A\u043E\u0442\u043E\u0440\u044B\u0439 \u0438 \u0437\u0430\u043F\u0443\u0441\u043A\u0430\u0435\u0442 \u0446\u0432\u0435\u0442\u0435\u043D\u0438\u0435. \u041F\u043E\u0441\u043B\u0435 \u0432\u044B\u0434\u0435\u0440\u0436\u0438\u0432\u0430\u043D\u0438\u044F \u043D\u0430 \u0445\u043E\u043B\u043E\u0434\u0443, \u044D\u043A\u0441\u043F\u0440\u0435\u0441\u0441\u0438\u044F FLC \u0441\u043D\u0438\u0436\u0430\u0435\u0442\u0441\u044F \u043F\u0440\u043E\u043F\u043E\u0440\u0446\u0438\u043E\u043D\u0430\u043B\u044C\u043D\u043E \u043F\u043E\u043D\u0438\u0436\u0435\u043D\u0438\u044E \u0442\u0435\u043C\u043F\u0435\u0440\u0430\u0442\u0443\u0440\u044B \u0438 \u0446\u0432\u0435\u0442\u0435\u043D\u0438\u0435 \u0441\u0442\u0430\u043D\u043E\u0432\u0438\u0442\u0441\u044F \u0432\u043E\u0437\u043C\u043E\u0436\u043D\u044B\u043C. \u0412\u043E \u0432\u0440\u0435\u043C\u044F \u044F\u0440\u043E\u0432\u0438\u0437\u0430\u0446\u0438\u0438 \u0443\u0440\u043E\u0432\u0435\u043D\u044C FLC \u043F\u043E\u043D\u0438\u0436\u0430\u0435\u0442\u0441\u044F, \u0447\u0442\u043E \u0447\u0430\u0441\u0442\u0438\u0447\u043D\u043E \u0432\u044B\u0437\u0432\u0430\u043D\u043E \u0434\u0435\u0439\u0441\u0442\u0432\u0438\u0435\u043C \u0434\u0440\u0443\u0433\u043E\u0433\u043E \u0431\u0435\u043B\u043A\u0430 VIN3 (Vernalization Insensitive 3). VIN3 \u043F\u043E\u044F\u0432\u043B\u044F\u0435\u0442\u0441\u044F \u0432 \u0440\u0430\u0441\u0442\u0435\u043D\u0438\u0438 \u0442\u043E\u043B\u044C\u043A\u043E \u043F\u043E\u0441\u043B\u0435 \u0442\u043E\u0433\u043E, \u043A\u0430\u043A \u043E\u043D\u043E \u043F\u043E\u0434\u0432\u0435\u0440\u0433\u043B\u043E\u0441\u044C \u0432\u043E\u0437\u0434\u0435\u0439\u0441\u0442\u0432\u0438\u044E \u043D\u0438\u0437\u043A\u043E\u0439 \u0442\u0435\u043C\u043F\u0435\u0440\u0430\u0442\u0443\u0440\u044B, \u0438 \u043E\u043D \u043F\u043E\u0441\u0442\u0435\u043F\u0435\u043D\u043D\u043E \u0438\u0441\u0447\u0435\u0437\u0430\u0435\u0442 \u043F\u043E\u0441\u043B\u0435 \u0432\u043E\u0437\u0432\u0440\u0430\u0449\u0435\u043D\u0438\u044F \u0440\u0430\u0441\u0442\u0435\u043D\u0438\u044F \u0432 \u0431\u043E\u043B\u0435\u0435 \u0442\u0451\u043F\u043B\u044B\u0435 \u0443\u0441\u043B\u043E\u0432\u0438\u044F. \u041F\u043E\u0441\u043B\u0435 \u0438\u0441\u0447\u0435\u0437\u043D\u043E\u0432\u0435\u043D\u0438\u044F VIN3 \u0431\u0435\u043B\u043A\u0438 VRN1 (Vernalization1) \u0438 VRN2 (Vernalization2) \u043F\u043E\u0434\u0434\u0435\u0440\u0436\u0438\u0432\u0430\u044E\u0442 \u043D\u0438\u0437\u043A\u0438\u0439 \u0443\u0440\u043E\u0432\u0435\u043D\u044C FLC. \u042D\u043A\u0441\u043F\u0440\u0435\u0441\u0441\u0438\u044F \u0433\u0435\u043D\u0430 FLC \u0440\u0435\u0433\u0443\u043B\u0438\u0440\u0443\u0435\u0442\u0441\u044F \u044D\u043F\u0438\u0433\u0435\u043D\u0435\u0442\u0438\u0447\u0435\u0441\u043A\u0438\u043C\u0438 \u043C\u043E\u0434\u0438\u0444\u0438\u043A\u0430\u0446\u0438\u044F\u043C\u0438 \u0438 \u0442\u0440\u0430\u043D\u0441\u043A\u0440\u0438\u043F\u0446\u0438\u043E\u043D\u043D\u044B\u043C \u043A\u043E\u043D\u0442\u0440\u043E\u043B\u0435\u043C. \u041D\u0430 \u044D\u043A\u0441\u043F\u0440\u0435\u0441\u0441\u0438\u044E FLC \u043E\u043A\u0430\u0437\u044B\u0432\u0430\u044E\u0442 \u0432\u043B\u0438\u044F\u043D\u0438\u0435 \u0434\u0440\u0443\u0433\u0438\u0435 \u0433\u0435\u043D\u044B, \u043D\u0430\u043F\u0440\u0438\u043C\u0435\u0440: , \u0438 (VRN2). \u0414\u0438\u043A\u0438\u0435 \u0440\u0430\u0441\u0442\u0435\u043D\u0438\u044F Arabidopsis \u043D\u0435\u0441\u0443\u0442 \u0440\u0430\u0437\u043D\u044B\u0435 \u0430\u043B\u043B\u0435\u043B\u0438 \u0433\u0435\u043D\u0430 FLC, \u0441\u043E\u043E\u0442\u0432\u0435\u0442\u0441\u0442\u0432\u0443\u044E\u0449\u0438\u0435 \u0440\u0430\u0437\u043D\u044B\u043C \u044D\u043A\u043E\u0442\u0438\u043F\u0430\u043C: (a) \u0437\u0430\u0446\u0432\u0435\u0442\u0430\u0435\u0442 \u0431\u044B\u0441\u0442\u0440\u043E \u0438 \u0434\u0430\u0451\u0442 \u043C\u043D\u043E\u0436\u0435\u0441\u0442\u0432\u043E \u043F\u043E\u043A\u043E\u043B\u0435\u043D\u0438\u0439 \u0437\u0430 \u043E\u0434\u043D\u043E \u043B\u0435\u0442\u043E \u0438\u043B\u0438 (b) \u0446\u0432\u0435\u0442\u0451\u0442 \u0442\u043E\u043B\u044C\u043A\u043E \u043F\u043E\u0441\u043B\u0435 \u044F\u0440\u043E\u0432\u0438\u0437\u0430\u0446\u0438\u0438. \u0422\u0430\u043A\u0430\u044F \u0432\u0430\u0440\u0438\u0430\u0431\u0438\u043B\u044C\u043D\u043E\u0441\u0442\u044C \u0442\u0430\u043A\u0436\u0435 \u043C\u043E\u0436\u0435\u0442 \u0431\u044B\u0442\u044C \u0432\u044B\u0437\u0432\u0430\u043D\u0430 \u0440\u0430\u0437\u043D\u044B\u043C\u0438 \u0430\u043B\u043B\u0435\u043B\u044F\u043C\u0438 \u0433\u0435\u043D\u0430 (FRI)."@ru . . . . . . . .