. . . "Holtfreter's solution (Holtfreter's medium) is a balanced salt solution that was developed by the developmental biologist Johannes Holtfreter for studying amphibian embryos and to reduce bacterial infections. As a specialised aqueous solution, it finds use in aquaria to prevent infections for early stage amphibians, where it is typically mixed with soft tap water. Amphibians such as axolotls prefer a hard water solution."@en . . . . . . "31332741"^^ . . . . . . . "Holtfreter's solution"@en . . . . . . . . . . . . . . . . . . . . . "1086099038"^^ . . . . . . . "Holtfreter's solution (Holtfreter's medium) is a balanced salt solution that was developed by the developmental biologist Johannes Holtfreter for studying amphibian embryos and to reduce bacterial infections. As a specialised aqueous solution, it finds use in aquaria to prevent infections for early stage amphibians, where it is typically mixed with soft tap water. Amphibians such as axolotls prefer a hard water solution."@en . "2003"^^ .