<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageExternalLink>	<https://dx.doi.org/10.1093/annonc/mdu180> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/property/symptoms>	"None, feeling tired, shortness of breath, easy bleeding, frequent infections"@en .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Myelodysplastic> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Myelodysplastic/myeloproliferative_disorder> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/property/icdo>	"9980"^^<http://www.w3.org/2001/XMLSchema#integer> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/treatment>	<http://dbpedia.org/resource/Stem_cell_transplantation> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Transient_myeloproliferative_disease> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2000/01/rdf-schema#comment>	"Les s\u00EDndromes mielodispl\u00E0stiques (SMD, abans coneguda com a \"pre-leuc\u00E8mia\") s\u00F3n un conjunt divers de trastorns hematol\u00F2gics (relacionats amb la sang) que inclouen la producci\u00F3 inefica\u00E7 (o displ\u00E0sia) de la classe mieloide de les c\u00E8l\u00B7lules de la sang. La SMD s'ha trobat en humans, gats i gossos. Les s\u00EDndromes mielodispl\u00E0stiques s\u00F3n trastorns de les c\u00E8l\u00B7lules mare en la medul\u00B7la \u00F2ssia. En la SMD, l'hematopoesi (producci\u00F3 de sang) \u00E9s desordenada i inefica\u00E7. El nombre i la qualitat de les c\u00E8l\u00B7lules formadores de sang disminueixen, reduint encara m\u00E9s la producci\u00F3 de sang."@ca .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2000/01/rdf-schema#comment>	"\u041C\u0456\u0454\u043B\u043E\u0434\u0438\u0441\u043F\u043B\u0430\u0441\u0442\u0438\u0301\u0447\u043D\u0456 \u0441\u0438\u043D\u0434\u0440\u043E\u0301\u043C\u0438 \u0430\u0431\u043E \u041C\u0414\u0421 (\u0430\u043D\u0433\u043B. Myelodysplastic syndromes) \u2014 \u0433\u0440\u0443\u043F\u0430 \u043D\u0430\u0431\u0443\u0442\u0438\u0445 \u0437\u043B\u043E\u044F\u043A\u0456\u0441\u043D\u0438\u0445 \u043A\u043B\u043E\u043D\u0430\u043B\u044C\u043D\u0438\u0445 \u043F\u043E\u0440\u0443\u0448\u0435\u043D\u044C \u0441\u0442\u043E\u0432\u0431\u0443\u0440\u043E\u0432\u0438\u0445 \u0433\u0435\u043C\u0430\u0442\u043E\u043F\u043E\u0435\u0442\u0438\u0447\u043D\u0438\u0445 \u043A\u043B\u0456\u0442\u0438\u043D, \u044F\u043A\u0456 \u043C\u0430\u044E\u0442\u044C \u0440\u0456\u0437\u043D\u043E\u043C\u0430\u043D\u0456\u0442\u043D\u0456 \u043A\u043B\u0456\u043D\u0456\u0447\u043D\u0456 \u043F\u0440\u043E\u044F\u0432\u0438, \u043C\u043E\u0440\u0444\u043E\u043B\u043E\u0433\u0456\u0447\u043D\u0456 \u0445\u0430\u0440\u0430\u043A\u0442\u0435\u0440\u0438\u0441\u0442\u0438\u043A\u0438 \u0442\u0430 \u0446\u0438\u0442\u043E\u0433\u0435\u043D\u0435\u0442\u0438\u0447\u043D\u0456 \u0430\u043D\u043E\u043C\u0430\u043B\u0456\u0457. \u041D\u0430\u0439\u0445\u0430\u0440\u0430\u043A\u0442\u0435\u0440\u043D\u0456\u0448\u0438\u043C \u043F\u0440\u043E\u044F\u0432\u043E\u043C \u041C\u0414\u0421 \u0454 \u043D\u0435\u0435\u0444\u0435\u043A\u0442\u0438\u0432\u043D\u0435 \u043A\u0440\u043E\u0432\u043E\u0442\u0432\u043E\u0440\u0435\u043D\u043D\u044F \u2014 \u0440\u043E\u0437\u0432\u0438\u0432\u0430\u0454\u0442\u044C\u0441\u044F \u043F\u0435\u0440\u0438\u0444\u0435\u0440\u0438\u0447\u043D\u0430 \u0446\u0438\u0442\u043E\u043F\u0435\u043D\u0456\u044F (\u043E\u0434\u043D\u043E-, \u0434\u0432\u043E- \u0447\u0438 \u0442\u0440\u0438\u0440\u043E\u0441\u0442\u043A\u043E\u0432\u0430)."@uk .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/medicalDiagnosis>	<http://dbpedia.org/resource/Bone_marrow_biopsy> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/property/wikiPageUsesTemplate>	<http://dbpedia.org/resource/Template:ICDO> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Karyogram> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2000/01/rdf-schema#label>	"\u9AA8\u9AD3\u589E\u751F\u5F02\u5E38\u7EFC\u5408\u5F81"@zh .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Hemoglobin> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2002/07/owl#sameAs>	<http://it.dbpedia.org/resource/Sindrome_mielodisplasica> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Azurophilic_granule> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Red_blood_cell> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Megakaryoblast> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Megakaryocyte> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Chloroma> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2000/01/rdf-schema#comment>	"Myelodysplastick\u00FD syndrom neboli MDS je onemocn\u011Bn\u00ED krvetvorby zp\u016Fsoben\u00E9 mutac\u00ED kmenov\u00E9 krvetvorn\u00E9 bu\u0148ky, kter\u00E1 vede k tvorb\u011B patologick\u00E9ho klonu bun\u011Bk jedn\u00E9 nebo v\u00EDce krevn\u00EDch \u0159ad. Jde tedy o \u201Eklon\u00E1ln\u00ED onemocn\u011Bn\u00ED kostn\u00ED d\u0159en\u011B\u201C. A\u010Dkoli se jedn\u00E1 p\u0159ev\u00E1\u017En\u011B o onemocn\u011Bn\u00ED star\u0161\u00EDch lid\u00ED, m\u016F\u017Ee postihnout i mlad\u0161\u00ED jedince."@cs .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2000/01/rdf-schema#comment>	"\uACE8\uC218\uC774\uD615\uC131\uC99D\uD6C4\uAD70(\u9AA8\u9AD3\u7570\u5F62\u6210\u75C7\u5019\u7FA4, myelodysplastic syndrome)\uC740 \uACE8\uC218\uC758 \uC870\uD608\uBAA8\uC138\uD3EC\uC5D0 \uBB38\uC81C\uAC00 \uC0DD\uAE30\uB294 \uC9C8\uBCD1\uC774\uB2E4. \uACE8\uC218 \uD615\uC131\uC774\uC0C1 \uC99D\uD6C4\uAD70\uC774\uB77C\uACE0\uB3C4 \uD55C\uB2E4. \uC801\uD608\uAD6C, \uBC31\uD608\uAD6C \uB4F1 \uD608\uC561 \uC138\uD3EC\uAC00 \uAC10\uC18C\uB418\uB294 \uC99D\uC0C1\uC774 \uC0DD\uAE30\uBA70 \uBE48\uD608\uC774\uB098 \uBC31\uD608\uBCD1 \uB4F1 \uB2E4\uB978 \uC9C8\uD658\uC758 \uC6D0\uC778\uC774 \uB420 \uC218 \uC788\uB2E4."@ko .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Radiation> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/property/treatment>	"Supportive care, medications, stem cell transplantation"@en .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/treatment>	<http://dbpedia.org/resource/Supportive_care> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/WikicatHematologicNeoplasms> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2000/01/rdf-schema#label>	"Syndrome my\u00E9lodysplasique"@fr .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/property/icd>	"238.7"^^<http://www.w3.org/2001/XMLSchema#double> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/property/wikiPageUsesTemplate>	<http://dbpedia.org/resource/Template:Infobox_medical_condition_(new)> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/5-azacytidine> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2002/07/owl#sameAs>	<http://lt.dbpedia.org/resource/Mielodisplastiniai_sindromai> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Trabecula> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2000/01/rdf-schema#comment>	"\u9AA8\u9AD3\u589E\u751F\u5F02\u5E38\u7EFC\u5408\u5F81\uFF08\u82F1\u8A9E\uFF1AMyelodysplastic syndromes\uFF0C\u7C21\u7A31MDS\uFF09\u53C8\u8B6F\u70BA\u9AA8\u9AD3\u767C\u80B2\u4E0D\u826F\u75C7\u5019\u7FA4\u3001\u9AA8\u9AD3\u751F\u6210\u4E0D\u826F\u75C7\u5019\u7FA4\u3001\u9AA8\u9AD3\u5316\u751F\u4E0D\u826F\u75C7\u5019\u7FA4\uFF0C\u70BA\u4E00\u7A2E\u56E0\u9AA8\u9AD3\u4E2D\u672A\u6210\u719F\u8840\u7403\u4E0D\u6B63\u5E38\u589E\u751F\u5C0E\u81F4\u7684\u8840\u764C\uFF0C\u4E14\u9019\u4E9B\u816B\u7624\u7D30\u80DE\u4E26\u4E0D\u6703\u8F49\u70BA\u6210\u719F\u8840\u7403\u7D30\u80DE\u3002\u60A3\u75C5\u521D\u671F\u4E00\u822C\u6C92\u6709\u75C7\u72C0\u3002\u75BE\u75C5\u665A\u671F\u75C7\u72C0\u5305\u542B\u75B2\u52DE\u3001\u547C\u5438\u56F0\u96BE\u3001\u6613\u51FA\u8840\uFF0C\u4E26\u6703\u589E\u52A0\u611F\u67D3\u98A8\u96AA\u3002\u6709\u4E9B\u578B\u5225\u751A\u81F3\u6703\u9032\u5C55\u5230\u6025\u6027\u9AA8\u9AD3\u6027\u767D\u8840\u75C5\u3002 \u98A8\u96AA\u56E0\u5B50\u5305\u542B\u904E\u53BB\u66FE\u63A5\u53D7\u904E\u5316\u7642\u6216\u653E\u7642\u3001\u66FE\u7D93\u63A5\u89F8\u904E\u67D0\u4E9B\u7279\u5B9A\u7684\u5316\u5B78\u7269\u8CEA\uFF0C\u5982\u3001\u8FB2\u85E5\u3001\u82EF\u3001\u6C5E\u6216\u925B\u7B49\u3002\u8840\u7403\u7D44\u6210\u7684\u6539\u8B8A\u53EF\u80FD\u6703\u5F15\u8D77\u7D05\u8840\u7403\u3001\uFF0C\u6216\u767D\u8840\u7403\u6E1B\u5C11\u3002\u6709\u4E9B\u578B\u6703\u5C0E\u81F4\u9AA8\u9AD3\u6216\u5468\u908A\u8840\u7684\u4E0D\u6210\u719F\u589E\u52A0\u3002MDS\u7684\u5206\u578B\u53EF\u900F\u904E\u5468\u908A\u8840\u6AA2\u548C\u9AA8\u9AD3\u8840\u7403\u6AA2\u67E5\u7684\u7279\u5B9A\u8B8A\u5316\u800C\u5B9A\u3002 \u6CBB\u7642\u65B9\u6CD5\u5305\u542B\u652F\u6301\u7642\u6CD5\u3001\u85E5\u7269\u7642\u6CD5\uFF0C\u4EE5\u53CA\u9AA8\u9AD3\u79FB\u690D\u3002\u652F\u6301\u7642\u6CD5\u5305\u542B\u8F38\u8840\u3001\uFF0C\u548C\u4F7F\u7528\u6297\u7EC6\u83CC\u836F\u3002\u6CBB\u7642\u85E5\u7269\u5305\u542B\u3001\uFF0C\u4EE5\u53CA\u963F\u624E\u80DE\u82F7\u7B49\u7B49\u3002\u6709\u4E9B\u75C5\u60A3\u53EF\u900F\u904E\u5316\u5B66\u7597\u6CD5\u5F8C\u7684\u9AA8\u9AD3\u79FB\u690D\u6CBB\u7652\u3002 \u7D04100,000\u67097\u4EBA\u7F79\u60A3MDS\uFF0C\u65B0\u767C\u75C5\u4F8B\u5247\u7D04\u6BCF\u5E74\u6BCF100,000\u4EBA4\u4F8B\u3002\u767C\u75C5\u5E74\u9F61\u5927\u7D04\u518D70\u6B72\u4E0A\u4E0B\u3002\u75C7\u72C0\u9700\u8996\u53D7\u5F71\u97FF\u7D30\u80DE\u7A2E\u985E\u3001\u8840\u4E2D\u82BD\u7D30\u80DE\u6578\u91CF\uFF0C\u4EE5\u53CA\u67D3\u8272\u9AD4\u8B8A\u5316\u7A0B\u5EA6\u800C\u5B9A\u3002\u8A72\u75C5\u8A3A\u65B7\u5F8C\u7684\u5E73\u5747\u5B58\u6D3B\u5E74\u4EFD\u7D04\u70BA2.5\u5E74\u3002\u8A72\u75C5\u6700\u65E9\u65BC1900\u5E74\u4EE3\u9996\u6B21\u767C\u73FE\uFF0C\u800C\u4ECA\u540D\u5247\u65BC1976\u5E74\u958B\u59CB\u4F7F\u7528\u3002"@zh .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Dyserythropoiesis> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Myeloblasts> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Flow_cytometry> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Hemolytic_anemia> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Clonal_hematopoiesis> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2002/07/owl#sameAs>	<http://www4.wiwiss.fu-berlin.de/diseasome/resource/diseases/789> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/White_blood_cell> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2002/07/owl#sameAs>	<http://yago-knowledge.org/resource/Myelodysplastic_syndrome> .
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<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Refractory_anemia_with_ring_sideroblasts> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Refractory_cytopenia_with_multilineage_dysplasia> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2000/01/rdf-schema#comment>	"Myelodysplasie of myelodysplastisch syndroom (MDS) staat voor een aantal stoornissen van het beenmerg waardoor de productie van bloedcellen is verstoord. Door een mutatie van de hematopo\u00EBtische stamcel gaat deze zich veelvuldig delen waarbij de normale hematopo\u00EBse wordt verdrongen en daardoor tekortschiet. Deze storing uit zich in de aanmaak van misvormde bloedcellen of bloedcellen die niet volledig uitrijpen. Het gevolg is een gebrek aan bloedplaatjes en aan rode en witte bloedcellen. Daarnaast bestaat het risico dat voorlopercellen zich ontwikkelen naar leukemie (in ca. 1/3 van de gevallen)."@nl .
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<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Agent_Orange> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/PsychologicalFeature100023100> .
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<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Pallor> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2000/01/rdf-schema#comment>	"La definizione di sindromi mielodisplasiche (dette anche mielodisplasie) si riferisce ad un insieme di anomalie delle cellule midollari le cui manifestazioni principali sono citopenia periferica e disemopoiesi. Gli aspetti displastici sono indicatori per diagnosticare tale sindrome. La mielodisplasia \u00E8 considerata una neoplasia mieloide ematica."@it .
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<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Isocitrate_dehydrogenase> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Osteoclast> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/property/caption>	"Blood smear from a person with myelodysplastic syndrome. A hypogranular neutrophil with a pseudo-Pelger-Huet nucleus is shown. There are also abnormally shaped red blood cells, in part related to removal of the spleen."@en .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Nitrosourea> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Refractory_anemia_with_excess_blasts> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/icd10>	"D46." .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Refractory_anemia_with_excess_blasts_in_transformation> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/symptom>	<http://dbpedia.org/resource/Infections> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Refractory_anemia_with_ringed_sideroblasts> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Cognition100023271> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Pat_Hingle> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Peripheral_blood> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Combination_medication> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Dyspnea> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2000/01/rdf-schema#comment>	"Los s\u00EDndromes mielodispl\u00E1sicos o anemia refractaria son un grupo de neoplasias hematol\u00F3gicas caracterizadas por diferenciaci\u00F3n anormal, dismorfolog\u00EDa y citopenias producidas por apoptosis exagerada de precursores hematopoy\u00E9ticos en la m\u00E9dula \u00F3sea, anormalidades cromos\u00F3micas, mutaciones gen\u00E9ticas som\u00E1ticas; que, en general, tienen tendencia a evolucionar a leucemia mieloide aguda.\u200B Ocurren con mayor frecuencia en personas mayores, pero tambi\u00E9n pueden acontecer en los j\u00F3venes.\u200B"@es .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Gain-of-function_mutation> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/property/wikiPageUsesTemplate>	<http://dbpedia.org/resource/Template:TOC_limit> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Embryogenesis> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Refractory_neutropenia> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2002/07/owl#sameAs>	<http://de.dbpedia.org/resource/Myelodysplastisches_Syndrom> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Deferasirox> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Monocytes> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Metaphase> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Deferiprone> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2002/07/owl#sameAs>	<http://sv.dbpedia.org/resource/Myelodysplastiskt_syndrom> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Deferoxamine> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Cellular_differentiation> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Pathology> .
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\u062A\u0639\u0631\u0641 \u0641\u064A \u0627\u0644\u0645\u0627\u0636\u064A \u0628\u0627\u0633\u0645 -\u0645\u064F\u0642\u064E\u062F\u0650\u0651\u0645\u0627\u062A\u064F \u0627\u0644\u0627\u0628\u0652\u064A\u0650\u0636\u0627\u0636- \u0648\u0647\u064A \u062D\u0627\u0644\u0629 \u0637\u0628\u064A\u0629 \u062A\u0646\u0637\u0648\u064A \u0639\u0644\u0649 \u0625\u0646\u062A\u0627\u062C \u062E\u0644\u0627\u064A\u0627 \u062F\u0645 \u0646\u0642\u0648\u064A\u0647 \u063A\u064A\u0631 \u0641\u0639\u0627\u0644\u0629. \u064A\u062A\u0635\u0641 \u0627\u0644\u0645\u0631\u0636 \u0628\u0623\u0646\u0647 \u0645\u062C\u0645\u0648\u0639\u0629 \u0645\u0646 \u0627\u0644\u0623\u0639\u0631\u0627\u0636 \u0627\u0644\u062A\u064A \u062A\u0624\u062F\u064A \u0625\u0644\u0649 \u0647\u0628\u0648\u0637 \u0643\u0644 \u0645\u0646 \u0643\u0631\u064A\u0627\u062A \u0627\u0644\u062F\u0645 \u0627\u0644\u062D\u0645\u0631\u0627\u0621 \u0648\u0627\u0644\u0628\u064A\u0636\u0627\u0621 \u0648\u0627\u0644\u0635\u0641\u0627\u0626\u062D \u0627\u0644\u062F\u0645\u0648\u064A\u0629. \u062A\u062D\u062F\u062B \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u063A\u0627\u0644\u0628\u0627 \u0639\u0646\u062F \u0627\u0644\u0628\u0627\u0644\u063A\u064A\u0646 \u0648\u0646\u0627\u062F\u0631\u0627 \u062D\u062F\u0648\u062B\u0647\u0627 \u0639\u0646\u062F \u0627\u0644\u0623\u0637\u0641\u0627\u0644 \u0623\u0648 \u062A\u062D\u062A \u0633\u0646 \u0627\u0644\u062E\u0645\u0633\u064A\u0646\u060C \u0648\u0645\u0639\u062F\u0644 \u0639\u0645\u0631 \u0627\u0644\u0645\u0631\u064A\u0636 \u0639\u0646\u062F \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u0645\u0627 \u0628\u064A\u0646 65-75 \u0639\u0627\u0645\u0627.\u063A\u0627\u0644\u0628\u0627\u064B \u0645\u0627 \u064A\u0635\u0628\u062D \u0644\u062F\u0649 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0645\u0635\u0627\u0628\u064A\u0646 \u0628\u0647\u0630\u0647 \u0627\u0644\u0645\u062A\u0644\u0627\u0632\u0645\u0647 \u0641\u0642\u0631 \u062F\u0645 \u062D\u0627\u062F\u060C \u0648\u064A\u062D\u062A\u0627\u062C\u0648\u0646 \u0644\u0646\u0642\u0644 \u062F\u0645 \u0645\u062A\u0643\u0631\u0631. \u0648\u0641\u064A \u0645\u0639\u0638\u0645 \u0627\u0644\u062D\u0627\u0644\u0627\u062A \u064A\u062A\u0641\u0627\u0642\u0645 \u0627\u0644\u0645\u0631\u0636\u060C \u0648\u064A\u0635\u0627\u0628 \u0627\u0644\u0645\u0631\u064A\u0636 \u0628\u0640 \u0642\u0644\u0629 \u0627\u0644\u0643\u0631\u064A\u0627\u062A \u0648\u0630\u0644\u0643 \u0628\u0633\u0628\u0628 \u0627\u0644\u0641\u0634\u0644 \u0627\u0644\u0645\u064F\u0637\u0631\u0650\u062F \u0644\u0646\u062E\u0627\u0639 \u0627\u0644\u0639\u0638\u0645. \u0648\u062A\u062A\u062D\u0648\u0644 \u0627\u0644\u0645\u062A\u0644\u0627\u0632\u0645\u0629 \u0644\u062F\u0649 \u062B\u0644\u062B \u0627\u0644\u0645\u0631\u0636\u0649 \u0625\u0644\u0649 \u0645\u0631\u0636 \u0633\u0631\u0637\u0627\u0646\u064A \u062E\u0628\u064A\u062B \u064A\u0633\u0645\u0649 \u0627\u0628\u064A\u0636\u0627\u0636 \u0627\u0644\u062F\u0645 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<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Hepatitis> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2000/01/rdf-schema#label>	"S\u00EDndrome mielodispl\u00E1sico"@es .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2002/07/owl#sameAs>	<http://bs.dbpedia.org/resource/Mijelodisplazijski_sindrom> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Refractory_thrombocytopenia> .
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<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Chronic_eosinophilic_leukemia> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2000/01/rdf-schema#label>	"Sindrome mielodisplasica"@it .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Vacuole> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Bleeding> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Blast_cell> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Spleen> .
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<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/abstract>	"Unter dem Begriff myelodysplastisches Syndrom (MDS, Myelodysplasie oder Plural myelodysplastische Syndrome) wird eine Gruppe von Erkrankungen des Knochenmarks zusammengefasst, bei denen die Blutbildung nicht von gesunden, sondern von genetisch ver\u00E4nderten Ursprungszellen (Stammzellen) ausgeht. Das Knochenmark von Patienten, die an myelodysplastischen Syndromen leiden, ist nicht mehr in der Lage, aus diesen Stammzellen vollst\u00E4ndig reife und funktionst\u00FCchtige Blutzellen zu bilden. In fortgeschrittenen Stadien dieser Erkrankungen werden immer mehr unreife Blutzellen produziert. Der Blutbildungsprozess ist also nachhaltig gest\u00F6rt und kann bei manchen Patienten zu einem sp\u00E4teren Zeitpunkt auch zu einer akuten myeloischen Leuk\u00E4mie (AML) f\u00FChren. Die myelodysplastischen Syndrome treten vor allem in h\u00F6herem Alter \u2013 ab ca. 60 Jahre \u2013 auf und verlaufen von Patient zu Patient sehr unterschiedlich. Das mediane Erkrankungsalter liegt bei ca. 75 Jahren, Frauen sind etwas seltener betroffen als M\u00E4nner. Die Behandlungsm\u00F6glichkeiten haben sich in den letzten Jahren entscheidend verbessert, sind aber angesichts der komplexen Krankheitsentstehung sehr differenziert und ber\u00FCcksichtigen vor allem die Unterscheidung in Niedrigrisiko- und Hochrisiko-MDS."@de .
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<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/abstract>	"S\u00EDndrome mielodispl\u00E1sica (SMD) refere-se a um grupo de neoplasias das c\u00E9lulas sangu\u00EDneas precursoras da medula \u00F3ssea, caracterizada por um aumento na quantidade das c\u00E9lulas imaturas, que podem se deslocar para ba\u00E7o e f\u00EDgado, e uma produ\u00E7\u00E3o de c\u00E9lulas sangu\u00EDneas ineficientes e anormais (anemia, leucopenia ou trombocitopenia). H\u00E1 um risco de 20 a 30% de se transformar em leucemia mieloide aguda. Todas as tr\u00EAs linhas celulares da medula \u00F3ssea podem estar envolvidas (s\u00E9rie branca ou granuloc\u00EDtica, s\u00E9rie vermelha ou eritroc\u00EDtica e s\u00E9rie plaquet\u00E1ria ou megacarioc\u00EDtica). A SMD \u00E9 mais comum em idosos com uma m\u00E9dia de idade de 70 anos. A cada ano aparecem 4 novos casos em cada 100.000 habitantes. H\u00E1 maior predomin\u00E2ncia desta doen\u00E7a no sexo masculino. A sobrevida m\u00E9dia \u00E9 de 2,5 a 3 anos."@pt .
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<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/abstract>	"Myelodysplasie of myelodysplastisch syndroom (MDS) staat voor een aantal stoornissen van het beenmerg waardoor de productie van bloedcellen is verstoord. Door een mutatie van de hematopo\u00EBtische stamcel gaat deze zich veelvuldig delen waarbij de normale hematopo\u00EBse wordt verdrongen en daardoor tekortschiet. Deze storing uit zich in de aanmaak van misvormde bloedcellen of bloedcellen die niet volledig uitrijpen. Het gevolg is een gebrek aan bloedplaatjes en aan rode en witte bloedcellen. Daarnaast bestaat het risico dat voorlopercellen zich ontwikkelen naar leukemie (in ca. 1/3 van de gevallen). De aandoening komt vooral voor onder ouderen (60 tot 80 jaar) en in die leeftijdsgroep wat meer bij mannen dan bij vrouwen. De behandeling is (vooral in de oudere leeftijdscategorie) vooral gericht op symptoombestrijding. Meer mensen overlijden ten gevolge van deze ziekte doordat ze te weinig bloedcellen hebben, dan ten gevolge van leukemie. Het is dus belangrijk dat mensen die aan deze ziekte lijden genoeg bloedplaatjes (trombocyten), witte bloedcellen (leukocyten) en rode bloedcellen (erytrocyten) hebben. Myelodysplasie komt in vele gradaties voor. De behandeling (eventueel chemotherapie en zelfs stamceltransplantaties) hangt hier dus ook sterk van af. Een belangrijke oorzaak van MDS is chemotherapie. Ook al klinkt het tegenstrijdig, maar sommige celdodende middelen kunnen op hun beurt ook weer een kwaadaardige beenmergziekte, namelijk MDS of acute myelo\u00EFde leukemie (AML) veroorzaken. Onder andere Susan Sontag en Gerrie M\u00FChren zijn hieraan overleden."@nl .
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<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/abstract>	"Myelodysplastiskt syndrom (MDS) \u00E4r en samlande beteckning f\u00F6r flera olika hematologiska tillst\u00E5nd som involverar felaktig bildning av myeloida eller blodbildande celler. Patienter med MDS utvecklar ofta en kraftig blodbrist, anemi, ofta kombinerat med brist p\u00E5 vita blodkroppar, leukopeni, och minskning av antalet blodpl\u00E4ttar, trombocytopeni. Myelodysplastiska sjukdomar beror p\u00E5 skador i blodbildande stamceller i benm\u00E4rgen. Hematopoesen (blodbildningen) blir ineffektiv och oordnad. Antalet blodkroppsbildande celler sjunker, vilket ger en allt s\u00E4mre blodnybildning. Patienterna behandlas ofta med t\u00E4ta blodtransfusioner. Hos ungef\u00E4r en tredjedel av patienterna med MDS \u00F6verg\u00E5r sjukdomen efter en tid till en akut myeloisk leukemi, AML, vanligtvis inom n\u00E5gon m\u00E5nad till ett par \u00E5r."@sv .
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<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/abstract>	"Myelodysplastick\u00FD syndrom neboli MDS je onemocn\u011Bn\u00ED krvetvorby zp\u016Fsoben\u00E9 mutac\u00ED kmenov\u00E9 krvetvorn\u00E9 bu\u0148ky, kter\u00E1 vede k tvorb\u011B patologick\u00E9ho klonu bun\u011Bk jedn\u00E9 nebo v\u00EDce krevn\u00EDch \u0159ad. Jde tedy o \u201Eklon\u00E1ln\u00ED onemocn\u011Bn\u00ED kostn\u00ED d\u0159en\u011B\u201C. A\u010Dkoli se jedn\u00E1 p\u0159ev\u00E1\u017En\u011B o onemocn\u011Bn\u00ED star\u0161\u00EDch lid\u00ED, m\u016F\u017Ee postihnout i mlad\u0161\u00ED jedince. V perifern\u00ED krvi doch\u00E1z\u00ED k pancytopenii neboli k sou\u010Dasn\u00E9mu poklesu po\u010Dtu v\u0161ech typ\u016F krevn\u00EDch bun\u011Bk, tedy \u010Derven\u00FDch a b\u00EDl\u00FDch krvinek a krevn\u00EDch desti\u010Dek. Naopak kostn\u00ED d\u0159e\u0148 m\u00E1 norm\u00E1ln\u00ED nebo nadm\u011Brn\u00FD po\u010Det bun\u011Bk se zn\u00E1mkami dysplazie. Zhruba v 10 % p\u0159\u00EDpad\u016F m\u016F\u017Ee m\u00EDt i sn\u00ED\u017Een\u00FD po\u010Det bun\u011Bk a je pak obt\u00ED\u017En\u011B rozli\u0161iteln\u00E1 od aplastick\u00E9 an\u00E9mie, co\u017E je \u201Echudokrevnost, kter\u00E1 m\u00E1 p\u016Fvod v nedostate\u010Dn\u00E9 tvorb\u011B krvinek v kostn\u00ED d\u0159eni\u201C. V pozdn\u00ED f\u00E1zi m\u016F\u017Ee MDS p\u0159ej\u00EDt do akutn\u00ED myeloidn\u00ED leukemie. Incidence je 4,5 nemocn\u00FDch na 100 tis\u00EDc obyvatel, v\u00FDskyt nemocn\u00FDch stoup\u00E1 u osob nad 60 let."@cs .
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<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/abstract>	"Les syndromes my\u00E9lodysplasiques (SMD, plus fr\u00E9quemment dits MDS pour myelodysplastic syndrome, en anciennement appel\u00E9s \u00AB an\u00E9mies r\u00E9fractaires \u00BB) sont des maladies de la moelle osseuse ou affections clonales my\u00E9lo\u00EFdes des cellules souches h\u00E9matopo\u00EF\u00E9tiques, qui ne sont pas des carences en mol\u00E9cules n\u00E9cessaires \u00E0 la synth\u00E8se de ces cellules. On a montr\u00E9 qu'une dysfonction des cellules prog\u00E9nitrices de l'os pouvaient induire une my\u00E9lodysplasie, secondairement suivie d'une leuc\u00E9mie. Les trois lign\u00E9es cellulaires sanguines (globules rouges, globules blancs et plaquettes) pr\u00E9sentent un trouble de diff\u00E9renciation qui aboutit \u00E0 une production insuffisante d'une, deux ou des trois sortes de cellules. De plus la moelle osseuse produit des cellules anormales dites \u00AB my\u00E9lodysplasiques \u00BB. Il s\u2019agit d\u2019une affection du sujet \u00E2g\u00E9, dont la m\u00E9diane d\u2019\u00E2ge au moment du diagnostic se situe aux environs de 70 ans. Chez l\u2019adulte, 8 \u00E0 10 % des cas surviennent en dessous de 50 ans. L'origine de ces maladies reste inconnue, probablement parfois g\u00E9n\u00E9tique (cong\u00E9nitale) ou due \u00E0 une mutation g\u00E9n\u00E9tique acquise. Des agents \u00AB environnementaux \u00BB sont possibles : une partie des patients atteints du syndrome my\u00E9lodysplasique a subi une chimioth\u00E9rapie (particuli\u00E8rement par des agents alkylants tels que le melphalan, gaz moutarde, cyclophosphamide, busulfan, et le chlorambucil) ou les radiations (th\u00E9rapeutiques ou accidentelles)."@fr .
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<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Binucleated_cells> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/property/medication>	<http://dbpedia.org/resource/Lenalidomide> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2002/07/owl#sameAs>	<http://fa.dbpedia.org/resource/\u0633\u0646\u062F\u0631\u0645_\u0645\u06CC\u0644\u0648\u062F\u06CC\u0633\u067E\u0644\u0627\u0633\u062A\u06CC\u06A9> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2000/01/rdf-schema#comment>	"\u9AA8\u9AC4\u7570\u5F62\u6210\u75C7\u5019\u7FA4\uFF08\u3053\u3064\u305A\u3044\u3044\u3051\u3044\u305B\u3044\u3057\u3087\u3046\u3053\u3046\u3050\u3093\u3001\u82F1: myelodysplastic syndromes\u3001\u7565\u79F0: MDS\uFF09\u3068\u306F\u9AA8\u9AC4\u6A5F\u80FD\u306E\u7570\u5E38\u306B\u3088\u3063\u3066\u524D\u767D\u8840\u75C5\u72B6\u614B\u3068\u306A\u308A\u3001\u9020\u8840\u969C\u5BB3\u3092\u8D77\u3053\u3059\u75C7\u5019\u7FA4\u3067\u3042\u308B\u3002"@ja .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Category:Wikipedia_medicine_articles_ready_to_translate> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Human_leukocyte_antigen> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Acquired_aplastic_anemia> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2002/07/owl#sameAs>	<http://he.dbpedia.org/resource/\u05D4\u05EA\u05E1\u05DE\u05D5\u05E0\u05EA_\u05D4\u05DE\u05D9\u05D0\u05DC\u05D5\u05D3\u05D9\u05E1\u05E4\u05DC\u05E1\u05D8\u05D9\u05EA> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Acute_megakaryoblastic_leukemia> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://www.wikidata.org/entity/Q12136> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Topoisomerase_inhibitor> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/property/medication>	<http://dbpedia.org/resource/Azacitidine> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Acute_myeloid_leukemia> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2002/07/owl#sameAs>	<http://hr.dbpedia.org/resource/Sindrom_mijelodisplazije> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Syndrome105870790> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/All-trans-retinoic_acid> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/thumbnail>	<http://commons.wikimedia.org/wiki/Special:FilePath/Hypogranular_neutrophil_with_a_pseudo-Pelger-Huet_nucleus_in_MDS.jpg?width=300> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Roald_Dahl> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/property/wikiPageUsesTemplate>	<http://dbpedia.org/resource/Template:Curlie> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/medication>	<http://dbpedia.org/resource/Antithymocyte_globulin> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2002/07/owl#sameAs>	<http://pl.dbpedia.org/resource/Zespo\u0142y_mielodysplastyczne> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2002/07/owl#sameAs>	<http://no.dbpedia.org/resource/Myelodysplastisk_syndrom> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2000/01/rdf-schema#comment>	"A myelodysplastic syndrome (MDS) is one of a group of cancers in which immature blood cells in the bone marrow do not mature, and as a result, do not develop into healthy blood cells. Early on, no symptoms typically are seen. Later, symptoms may include feeling tired, shortness of breath, bleeding disorders, anemia, or frequent infections. Some types may develop into acute myeloid leukemia."@en .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/abstract>	"\u9AA8\u9AD3\u589E\u751F\u5F02\u5E38\u7EFC\u5408\u5F81\uFF08\u82F1\u8A9E\uFF1AMyelodysplastic syndromes\uFF0C\u7C21\u7A31MDS\uFF09\u53C8\u8B6F\u70BA\u9AA8\u9AD3\u767C\u80B2\u4E0D\u826F\u75C7\u5019\u7FA4\u3001\u9AA8\u9AD3\u751F\u6210\u4E0D\u826F\u75C7\u5019\u7FA4\u3001\u9AA8\u9AD3\u5316\u751F\u4E0D\u826F\u75C7\u5019\u7FA4\uFF0C\u70BA\u4E00\u7A2E\u56E0\u9AA8\u9AD3\u4E2D\u672A\u6210\u719F\u8840\u7403\u4E0D\u6B63\u5E38\u589E\u751F\u5C0E\u81F4\u7684\u8840\u764C\uFF0C\u4E14\u9019\u4E9B\u816B\u7624\u7D30\u80DE\u4E26\u4E0D\u6703\u8F49\u70BA\u6210\u719F\u8840\u7403\u7D30\u80DE\u3002\u60A3\u75C5\u521D\u671F\u4E00\u822C\u6C92\u6709\u75C7\u72C0\u3002\u75BE\u75C5\u665A\u671F\u75C7\u72C0\u5305\u542B\u75B2\u52DE\u3001\u547C\u5438\u56F0\u96BE\u3001\u6613\u51FA\u8840\uFF0C\u4E26\u6703\u589E\u52A0\u611F\u67D3\u98A8\u96AA\u3002\u6709\u4E9B\u578B\u5225\u751A\u81F3\u6703\u9032\u5C55\u5230\u6025\u6027\u9AA8\u9AD3\u6027\u767D\u8840\u75C5\u3002 \u98A8\u96AA\u56E0\u5B50\u5305\u542B\u904E\u53BB\u66FE\u63A5\u53D7\u904E\u5316\u7642\u6216\u653E\u7642\u3001\u66FE\u7D93\u63A5\u89F8\u904E\u67D0\u4E9B\u7279\u5B9A\u7684\u5316\u5B78\u7269\u8CEA\uFF0C\u5982\u3001\u8FB2\u85E5\u3001\u82EF\u3001\u6C5E\u6216\u925B\u7B49\u3002\u8840\u7403\u7D44\u6210\u7684\u6539\u8B8A\u53EF\u80FD\u6703\u5F15\u8D77\u7D05\u8840\u7403\u3001\uFF0C\u6216\u767D\u8840\u7403\u6E1B\u5C11\u3002\u6709\u4E9B\u578B\u6703\u5C0E\u81F4\u9AA8\u9AD3\u6216\u5468\u908A\u8840\u7684\u4E0D\u6210\u719F\u589E\u52A0\u3002MDS\u7684\u5206\u578B\u53EF\u900F\u904E\u5468\u908A\u8840\u6AA2\u548C\u9AA8\u9AD3\u8840\u7403\u6AA2\u67E5\u7684\u7279\u5B9A\u8B8A\u5316\u800C\u5B9A\u3002 \u6CBB\u7642\u65B9\u6CD5\u5305\u542B\u652F\u6301\u7642\u6CD5\u3001\u85E5\u7269\u7642\u6CD5\uFF0C\u4EE5\u53CA\u9AA8\u9AD3\u79FB\u690D\u3002\u652F\u6301\u7642\u6CD5\u5305\u542B\u8F38\u8840\u3001\uFF0C\u548C\u4F7F\u7528\u6297\u7EC6\u83CC\u836F\u3002\u6CBB\u7642\u85E5\u7269\u5305\u542B\u3001\uFF0C\u4EE5\u53CA\u963F\u624E\u80DE\u82F7\u7B49\u7B49\u3002\u6709\u4E9B\u75C5\u60A3\u53EF\u900F\u904E\u5316\u5B66\u7597\u6CD5\u5F8C\u7684\u9AA8\u9AD3\u79FB\u690D\u6CBB\u7652\u3002 \u7D04100,000\u67097\u4EBA\u7F79\u60A3MDS\uFF0C\u65B0\u767C\u75C5\u4F8B\u5247\u7D04\u6BCF\u5E74\u6BCF100,000\u4EBA4\u4F8B\u3002\u767C\u75C5\u5E74\u9F61\u5927\u7D04\u518D70\u6B72\u4E0A\u4E0B\u3002\u75C7\u72C0\u9700\u8996\u53D7\u5F71\u97FF\u7D30\u80DE\u7A2E\u985E\u3001\u8840\u4E2D\u82BD\u7D30\u80DE\u6578\u91CF\uFF0C\u4EE5\u53CA\u67D3\u8272\u9AD4\u8B8A\u5316\u7A0B\u5EA6\u800C\u5B9A\u3002\u8A72\u75C5\u8A3A\u65B7\u5F8C\u7684\u5E73\u5747\u5B58\u6D3B\u5E74\u4EFD\u7D04\u70BA2.5\u5E74\u3002\u8A72\u75C5\u6700\u65E9\u65BC1900\u5E74\u4EE3\u9996\u6B21\u767C\u73FE\uFF0C\u800C\u4ECA\u540D\u5247\u65BC1976\u5E74\u958B\u59CB\u4F7F\u7528\u3002"@zh .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/property/field>	<http://dbpedia.org/resource/Oncology> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/property/risks>	"Previous chemotherapy, radiation therapy, certain chemicals such as tobacco smoke, pesticides, and benzene, exposure to mercury or lead"@en .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/French-American-British_classification> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Auer_rods> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/ICD-O> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Acute_leukemia> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2000/01/rdf-schema#comment>	"Zespo\u0142y mielodysplastyczne (mielodysplazja szpiku) (ang. myelodysplastic syndrome, MDS) \u2013 klonalne zaburzenie hematopoetycznej kom\u00F3rki macierzystej uniemo\u017Cliwiaj\u0105ce r\u00F3\u017Cnicowanie i dojrzewanie kom\u00F3rek, przejawiaj\u0105ce si\u0119 jedno-, dwu- lub tr\u00F3jliniow\u0105 cytopeni\u0105 i najcz\u0119\u015Bciej bogatokom\u00F3rkowym szpikiem. Jest to grupa blisko zwi\u0105zanych jednostek chorobowych, w kt\u00F3rych proces tworzenia krwinek jest zak\u0142\u00F3cony przez niezdolno\u015B\u0107 niedojrza\u0142ych kom\u00F3rek do prawid\u0142owego wzrostu i rozwoju. Czasami nazywany stanem przedbia\u0142aczkowym, poniewa\u017C w zaawansowanych postaciach stosunkowo cz\u0119sto transformuje w kierunku ostrych bia\u0142aczek."@pl .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2002/07/owl#sameAs>	<http://la.dbpedia.org/resource/Syndroma_myelodysplastica> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Transfusions> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Apoptosis> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Medical_history> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/abstract>	"La definizione di sindromi mielodisplasiche (dette anche mielodisplasie) si riferisce ad un insieme di anomalie delle cellule midollari le cui manifestazioni principali sono citopenia periferica e disemopoiesi. Gli aspetti displastici sono indicatori per diagnosticare tale sindrome. La mielodisplasia \u00E8 considerata una neoplasia mieloide ematica."@it .
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<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/abstract>	"A myelodysplastic syndrome (MDS) is one of a group of cancers in which immature blood cells in the bone marrow do not mature, and as a result, do not develop into healthy blood cells. Early on, no symptoms typically are seen. Later, symptoms may include feeling tired, shortness of breath, bleeding disorders, anemia, or frequent infections. Some types may develop into acute myeloid leukemia. Risk factors include previous chemotherapy or radiation therapy, exposure to certain chemicals such as tobacco smoke, pesticides, and benzene, and exposure to heavy metals such as mercury or lead. Problems with blood cell formation result in some combination of low red blood cell, platelet, and white blood cell counts. Some types have an increase in immature blood cells, called blasts, in the bone marrow or blood. The types of MDS are based on specific changes in the blood cells and bone marrow. Treatments may include supportive care, drug therapy, and hematopoietic stem cell transplantation. Supportive care may include blood transfusions, medications to increase the making of red blood cells, and antibiotics. Drug therapy may include the medications lenalidomide, antithymocyte globulin, and azacitidine. Certain people can be cured with chemotherapy followed by a stem-cell transplant from a donor. About seven per 100,000 people are affected, with about four per 100,000 people newly acquiring the condition each year. The typical age of onset is 70 years. The outlook depends on the type of cells affected, the number of blasts in the bone marrow or blood, and the changes present in the chromosomes of the affected cells. The typical survival time following diagnosis is 2.5 years. The conditions were first recognized in the early 1900s. The current name came into use in 1976."@en .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2000/01/rdf-schema#comment>	"Unter dem Begriff myelodysplastisches Syndrom (MDS, Myelodysplasie oder Plural myelodysplastische Syndrome) wird eine Gruppe von Erkrankungen des Knochenmarks zusammengefasst, bei denen die Blutbildung nicht von gesunden, sondern von genetisch ver\u00E4nderten Ursprungszellen (Stammzellen) ausgeht. Das Knochenmark von Patienten, die an myelodysplastischen Syndromen leiden, ist nicht mehr in der Lage, aus diesen Stammzellen vollst\u00E4ndig reife und funktionst\u00FCchtige Blutzellen zu bilden."@de .
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<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2000/01/rdf-schema#comment>	"Les syndromes my\u00E9lodysplasiques (SMD, plus fr\u00E9quemment dits MDS pour myelodysplastic syndrome, en anciennement appel\u00E9s \u00AB an\u00E9mies r\u00E9fractaires \u00BB) sont des maladies de la moelle osseuse ou affections clonales my\u00E9lo\u00EFdes des cellules souches h\u00E9matopo\u00EF\u00E9tiques, qui ne sont pas des carences en mol\u00E9cules n\u00E9cessaires \u00E0 la synth\u00E8se de ces cellules. On a montr\u00E9 qu'une dysfonction des cellules prog\u00E9nitrices de l'os pouvaient induire une my\u00E9lodysplasie, secondairement suivie d'une leuc\u00E9mie."@fr .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Dyscrasia114053717> .
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<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/abstract>	"Les s\u00EDndromes mielodispl\u00E0stiques (SMD, abans coneguda com a \"pre-leuc\u00E8mia\") s\u00F3n un conjunt divers de trastorns hematol\u00F2gics (relacionats amb la sang) que inclouen la producci\u00F3 inefica\u00E7 (o displ\u00E0sia) de la classe mieloide de les c\u00E8l\u00B7lules de la sang. La SMD s'ha trobat en humans, gats i gossos. Els pacients amb SMD sovint desenvolupen an\u00E8mia severa i requereixen transfusions de sang freq\u00FCents. En la majoria dels casos, la malaltia empitjora i el pacient desenvolupa citop\u00E8nies (recomptes baixos de c\u00E8l\u00B7lules sangu\u00EDnies), a causa del deteriorament progressiu de la medul\u00B7la \u00F2ssia. En al voltant d'un ter\u00E7 dels pacients amb SMD, la malaltia es transforma en la leuc\u00E8mia mieloide aguda (LMA), en general en q\u00FCesti\u00F3 de mesos a uns anys. Les s\u00EDndromes mielodispl\u00E0stiques s\u00F3n trastorns de les c\u00E8l\u00B7lules mare en la medul\u00B7la \u00F2ssia. En la SMD, l'hematopoesi (producci\u00F3 de sang) \u00E9s desordenada i inefica\u00E7. El nombre i la qualitat de les c\u00E8l\u00B7lules formadores de sang disminueixen, reduint encara m\u00E9s la producci\u00F3 de sang. A Catalunya, t\u00E9 una taxa de superviv\u00E8ncia a cinc anys per a homes al voltant del 44% i per a dones al voltant del 37%."@ca .
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<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Myeloproliferative_syndrome> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/WikicatSyndromes> .
<http://dbpedia.org/resource/Myelodysplastic_syndrome>	<http://www.w3.org/2000/01/rdf-schema#comment>	"S\u00EDndrome mielodispl\u00E1sica (SMD) refere-se a um grupo de neoplasias das c\u00E9lulas sangu\u00EDneas precursoras da medula \u00F3ssea, caracterizada por um aumento na quantidade das c\u00E9lulas imaturas, que podem se deslocar para ba\u00E7o e f\u00EDgado, e uma produ\u00E7\u00E3o de c\u00E9lulas sangu\u00EDneas ineficientes e anormais (anemia, leucopenia ou trombocitopenia). H\u00E1 um risco de 20 a 30% de se transformar em leucemia mieloide aguda. Todas as tr\u00EAs linhas celulares da medula \u00F3ssea podem estar envolvidas (s\u00E9rie branca ou granuloc\u00EDtica, s\u00E9rie vermelha ou eritroc\u00EDtica e s\u00E9rie plaquet\u00E1ria ou megacarioc\u00EDtica)."@pt .
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