. . . . . . . . . . . . . . . . . . "A noxious stimulus is a stimulus strong enough to threaten the body\u2019s integrity (i.e. cause damage to tissue). Noxious stimulation induces peripheral afferents responsible for transducing pain (including A-delta and C- nerve fibers, as well as free nerve endings), throughout the nervous system of an organism. Because of rare genetic conditions that inhibit the ability to perceive physical pain, such as congenital insensitivity to pain and anhydrosis (CIPA), noxious stimulation does not invariably lead to tissue damage."@en . . . . . . . . . "Noxious stimulus"@pt . "Noxious stimulus"@en . "Um noxious stimulus \u00E9 \"um evento real ou potencialmente danoso ao tecido\". \u00C9 um pr\u00E9-requisito para a nocicep\u00E7\u00E3o, que em si \u00E9 um pr\u00E9-requisito para a dor nociceptiva. O noxious stimuli pode ser tanto mec\u00E2nico (por exemplo, ou outra deforma\u00E7\u00E3o do tecido), qu\u00EDmico (por exemplo, exposi\u00E7\u00E3o a \u00E1cidos ou ), ou t\u00E9rmico (por exemplo, temperaturas elevadas ou baixas)."@pt . "3004"^^ . "A noxious stimulus is a stimulus strong enough to threaten the body\u2019s integrity (i.e. cause damage to tissue). Noxious stimulation induces peripheral afferents responsible for transducing pain (including A-delta and C- nerve fibers, as well as free nerve endings), throughout the nervous system of an organism. The ability to perceive noxious stimuli is a prerequisite for nociception, which itself is a prerequisite for nociceptive pain. A noxious stimulus has been seen to drives nocifensive behavioral responses, which are responses to noxious or painful stimuli. These include reflexive, escape behaviors, to avoid harm to an organism's body. Because of rare genetic conditions that inhibit the ability to perceive physical pain, such as congenital insensitivity to pain and anhydrosis (CIPA), noxious stimulation does not invariably lead to tissue damage. Noxious stimuli can either be mechanical (e.g. pinching or other tissue deformation), chemical (e.g. exposure to acid or irritant), or thermal (e.g. high or low temperatures). There are some types of tissue damage that are not detected by any sensory receptors, and thus cannot cause pain. Therefore, not all noxious stimuli are adequate stimuli of nociceptors. The adequate stimuli of nociceptors are termed nociceptive stimuli."@en . . "19697528"^^ . . . . . . "Um noxious stimulus \u00E9 \"um evento real ou potencialmente danoso ao tecido\". \u00C9 um pr\u00E9-requisito para a nocicep\u00E7\u00E3o, que em si \u00E9 um pr\u00E9-requisito para a dor nociceptiva. O noxious stimuli pode ser tanto mec\u00E2nico (por exemplo, ou outra deforma\u00E7\u00E3o do tecido), qu\u00EDmico (por exemplo, exposi\u00E7\u00E3o a \u00E1cidos ou ), ou t\u00E9rmico (por exemplo, temperaturas elevadas ou baixas). Existem alguns tipos de danos aos tecidos que n\u00E3o s\u00E3o detectados por quaisquer receptores sensoriais, e, assim, n\u00E3o podem causar dor. Portanto, nem todos os noxious stimuli s\u00E3o est\u00EDmulos adequados dos nociceptores. Os est\u00EDmulos adequados dos nociceptores s\u00E3o denominados . Um est\u00EDmulo nociceptivo \u00E9 definido como \"\"um evento real ou potencialmente danoso ao tecido transduzido e codificado por nociceptores.\""@pt . . . . . . . . "1108425586"^^ .