. . . . "Platinum-based antineoplastic drugs (informally called platins) are chemotherapeutic agents used to treat cancer. They are coordination complexes of platinum. These drugs are used to treat almost half of people receiving chemotherapy for cancer. In this form of chemotherapy, commonly used drugs include cisplatin, oxaliplatin, and carboplatin, but several have been proposed or are under development. Addition of platinum-based chemotherapy drugs to chemoradiation in women with early cervical cancer seems to improve survival and reduce risk of recurrence."@en . . . . "36491756"^^ . . . . . . . . . . . "1082533784"^^ . . "Les sels de platine sont une classe de m\u00E9dicaments de chimioth\u00E9rapie. Cette classe regroupe trois mol\u00E9cules couramment utilis\u00E9es : le cisplatine, l'oxaliplatine, et le carboplatine. Ce sont des agents alkylants de l'ADN, qui inhibent la r\u00E9plication cellulaire et induisent la mort cellulaire pr\u00E9f\u00E9rentielle des cellules canc\u00E9reuses."@fr . . . . . . . . . . . "\u041F\u0440\u0435\u043F\u0430\u0440\u0430\u0301\u0442\u044B \u043F\u043B\u0430\u0301\u0442\u0438\u043D\u044B \u2014 \u0446\u0438\u0442\u043E\u0441\u0442\u0430\u0442\u0438\u0447\u0435\u0441\u043A\u0438\u0435 \u043F\u0440\u043E\u0442\u0438\u0432\u043E\u043E\u043F\u0443\u0445\u043E\u043B\u0435\u0432\u044B\u0435 \u0445\u0438\u043C\u0438\u043E\u0442\u0435\u0440\u0430\u043F\u0435\u0432\u0442\u0438\u0447\u0435\u0441\u043A\u0438\u0435 \u043B\u0435\u043A\u0430\u0440\u0441\u0442\u0432\u0435\u043D\u043D\u044B\u0435 \u043F\u0440\u0435\u043F\u0430\u0440\u0430\u0442\u044B \u0430\u043B\u043A\u0438\u043B\u0438\u0440\u0443\u044E\u0449\u0435\u0433\u043E \u0442\u0438\u043F\u0430, \u0441\u043E\u0434\u0435\u0440\u0436\u0430\u0449\u0438\u0435 \u0432 \u0441\u043E\u0441\u0442\u0430\u0432\u0435 \u043C\u043E\u043B\u0435\u043A\u0443\u043B \u0434\u0432\u0443\u0445\u0432\u0430\u043B\u0435\u043D\u0442\u043D\u0443\u044E \u043F\u043B\u0430\u0442\u0438\u043D\u0443 (II) \u0438 \u043D\u0435\u0444\u043E\u0440\u043C\u0430\u043B\u044C\u043D\u043E \u043D\u0430\u0437\u044B\u0432\u0430\u0435\u043C\u044B\u0435 \u043F\u0440\u043E\u0441\u0442\u043E \u00AB\u043F\u043B\u0430\u0442\u0438\u043D\u043E\u0439\u00BB. \u0412\u0441\u0435 \u044D\u0442\u0438 \u043F\u0440\u0435\u043F\u0430\u0440\u0430\u0442\u044B \u044F\u0432\u043B\u044F\u044E\u0442\u0441\u044F \u043A\u043E\u043E\u0440\u0434\u0438\u043D\u0430\u0446\u0438\u043E\u043D\u043D\u044B\u043C\u0438 \u043A\u043E\u043C\u043F\u043B\u0435\u043A\u0441\u0430\u043C\u0438 \u0434\u0432\u0443\u0445\u0432\u0430\u043B\u0435\u043D\u0442\u043D\u043E\u0439 \u043F\u043B\u0430\u0442\u0438\u043D\u044B."@ru . . . . . . "\u041F\u0440\u0435\u043F\u0430\u0440\u0430\u0301\u0442\u044B \u043F\u043B\u0430\u0301\u0442\u0438\u043D\u044B \u2014 \u0446\u0438\u0442\u043E\u0441\u0442\u0430\u0442\u0438\u0447\u0435\u0441\u043A\u0438\u0435 \u043F\u0440\u043E\u0442\u0438\u0432\u043E\u043E\u043F\u0443\u0445\u043E\u043B\u0435\u0432\u044B\u0435 \u0445\u0438\u043C\u0438\u043E\u0442\u0435\u0440\u0430\u043F\u0435\u0432\u0442\u0438\u0447\u0435\u0441\u043A\u0438\u0435 \u043B\u0435\u043A\u0430\u0440\u0441\u0442\u0432\u0435\u043D\u043D\u044B\u0435 \u043F\u0440\u0435\u043F\u0430\u0440\u0430\u0442\u044B \u0430\u043B\u043A\u0438\u043B\u0438\u0440\u0443\u044E\u0449\u0435\u0433\u043E \u0442\u0438\u043F\u0430, \u0441\u043E\u0434\u0435\u0440\u0436\u0430\u0449\u0438\u0435 \u0432 \u0441\u043E\u0441\u0442\u0430\u0432\u0435 \u043C\u043E\u043B\u0435\u043A\u0443\u043B \u0434\u0432\u0443\u0445\u0432\u0430\u043B\u0435\u043D\u0442\u043D\u0443\u044E \u043F\u043B\u0430\u0442\u0438\u043D\u0443 (II) \u0438 \u043D\u0435\u0444\u043E\u0440\u043C\u0430\u043B\u044C\u043D\u043E \u043D\u0430\u0437\u044B\u0432\u0430\u0435\u043C\u044B\u0435 \u043F\u0440\u043E\u0441\u0442\u043E \u00AB\u043F\u043B\u0430\u0442\u0438\u043D\u043E\u0439\u00BB. \u0412\u0441\u0435 \u044D\u0442\u0438 \u043F\u0440\u0435\u043F\u0430\u0440\u0430\u0442\u044B \u044F\u0432\u043B\u044F\u044E\u0442\u0441\u044F \u043A\u043E\u043E\u0440\u0434\u0438\u043D\u0430\u0446\u0438\u043E\u043D\u043D\u044B\u043C\u0438 \u043A\u043E\u043C\u043F\u043B\u0435\u043A\u0441\u0430\u043C\u0438 \u0434\u0432\u0443\u0445\u0432\u0430\u043B\u0435\u043D\u0442\u043D\u043E\u0439 \u043F\u043B\u0430\u0442\u0438\u043D\u044B."@ru . . "\u041F\u0440\u0435\u043F\u0430\u0440\u0430\u0442\u044B \u043F\u043B\u0430\u0442\u0438\u043D\u044B"@ru . "Sel de platine"@fr . . . . . . . . . . . . "7219"^^ . . . . "Les sels de platine sont une classe de m\u00E9dicaments de chimioth\u00E9rapie. Cette classe regroupe trois mol\u00E9cules couramment utilis\u00E9es : le cisplatine, l'oxaliplatine, et le carboplatine. Ce sont des agents alkylants de l'ADN, qui inhibent la r\u00E9plication cellulaire et induisent la mort cellulaire pr\u00E9f\u00E9rentielle des cellules canc\u00E9reuses."@fr . . . . . "Platinum-based antineoplastic"@en . . . . . . . . . "Platinum-based antineoplastic drugs (informally called platins) are chemotherapeutic agents used to treat cancer. They are coordination complexes of platinum. These drugs are used to treat almost half of people receiving chemotherapy for cancer. In this form of chemotherapy, commonly used drugs include cisplatin, oxaliplatin, and carboplatin, but several have been proposed or are under development. Addition of platinum-based chemotherapy drugs to chemoradiation in women with early cervical cancer seems to improve survival and reduce risk of recurrence. In total, these drugs can cause a combination of more than 40 specific side effects which include neurotoxicity, which is manifested by peripheral neuropathies including polyneuropathy."@en . . .