The 1960 Penn Quakers football team was an American football team that represented the University of Pennsylvania during the 1960 NCAA University Division football season. A year after winning the Ivy League, Penn dropped to sixth place in 1960. In their first year under head coach John Stiegman, the Quakers compiled a 3–6 record and were outscored 149 to 104. George Koval was the team captain. Penn's 2–5 conference record was the sixth-best in the Ivy League standings. The Quakers were outscored 108 to 69 by Ivy opponents.