The 2010 Total 24 Hours of Spa was the 63rd running of the Spa 24 Hours. Following the break-up of the FIA GT Championship, the 2010 running of the Spa 24 Hours served as part of the FIA GT2 European Cup, with cars from the GT3, GT4, and national-level GT categories also being allowed to participate. Due to a transaxle gearbox the BMW M3 GT2 was not allowed to compete in the GT2 class, forcing them to race in GTN instead. This was the last year GT2 cars were eligible for the race.