The 2016–17 George Mason Patriots women's basketball team represents George Mason University during the 2016–17 NCAA Division I women's basketball season. The Patriots, led by third year head coach Nyla Milleson, played their home games at EagleBank Arena and were members of the Atlantic 10 Conference. They finished the season 13–17, 6–10 in A-10 play to finish in tenth place. They lost in the first round of the A-10 women's tournament to Duquesne.