The 2018–19 Drexel Dragons women's basketball team represents Drexel University during the 2018–19 NCAA Division I women's basketball season. The Dragons, led by sixteenth-year head coach Denise Dillon, play their home games at the Daskalakis Athletic Center in Philadelphia, Pennsylvania as members of the Colonial Athletic Association. They finished the season 24–9, 14–4 in CAA play to finish in second place. They advanced to the championship game of the CAA women's tournament where they lost to Towson. They received an at-large bid to the Women's National Invitational Tournament where they lost in the first round to Harvard.