The 2018–19 UEFA Youth League knockout phase (play-offs and round of 16 onwards) began on 19 February and concluded on 29 April 2019 with the final at Colovray Stadium in Nyon, Switzerland. It decided the champions of the 2018–19 UEFA Youth League. A total of 24 teams competed in the knockout phase (play-offs and round of 16 onwards). Times are CET/CEST, as listed by UEFA (local times, if different, are in parentheses).