The 2020–21 Grand Canyon Antelopes men's basketball team represented Grand Canyon University during the 2020–21 NCAA Division I men's basketball season. They are led by head coach Bryce Drew in his first season. The Antelopes play their home games at GCU Arena in Phoenix, Arizona as members of the Western Athletic Conference. They finished the season 17-7, 9-3 in WAC Play to finish a tie for the regular season championship. They defeated Seattle and New Mexico State to win the WAC tournament. They received the conference’s automatic bid to the NCAA tournament where they lost in the first round to Iowa.