The 2022 Blue-Emu Maximum Pain Relief 200 was the fifth stock car race of the 2022 NASCAR Camping World Truck Series and the 20th iteration of the event. The race was held on Thursday, April 7, 2022, in Martinsville, Virginia at Martinsville Speedway, a 0.526 miles (0.847 km) permanent oval-shaped short track. The race was run over 200 laps. William Byron of Spire Motorsports would win the race after leading 94 laps. This was Byron's eighth career truck series win, and his first of the season. This was also the second win for Spire Motorsports in NASCAR. To fill out the podium, Johnny Sauter of ThorSport Racing and Kyle Busch of Kyle Busch Motorsports would finish 2nd and 3rd, respectively.