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DNA binding sites are a type of binding site found in DNA where other molecules may bind. DNA binding sites are distinct from other binding sites in that (1) they are part of a DNA sequence (e.g. a genome) and (2) they are bound by DNA-binding proteins. DNA binding sites are often associated with specialized proteins known as transcription factors, and are thus linked to transcriptional regulation. The sum of DNA binding sites of a specific transcription factor is referred to as its cistrome. DNA binding sites also encompasses the targets of other proteins, like restriction enzymes, site-specific recombinases (see site-specific recombination) and methyltransferases.

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  • مواقع ربط الحمض النووي (ar)
  • DNA binding site (en)
  • DNA结合位点 (zh)
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  • DNA结合位点(英語:DNA binding sites)是存在于DNA上的与其它分子相绑定的各类结合位点。 DNA结合位点与其它结合位点的区别在于: * 它们是DNA序列(如一个基因组)中的一部分; * 它们被所绑定。 DNA结合位点常常与一类被称为转录因子的特殊蛋白相联系起来,并因此联系到转录调控。针对特定的一个转录因子的DNA结合位点总和常被命名为该转录因子的顺反组。DNA结合位点也包括了其它蛋白的靶点,如限制性核酸内切酶、位点特异性重组酶(见)及类。 因此,DNA结合位点可被定义为:特异性地被一种或多种或蛋白复合物所结合的一段短DNA序列(典型的是4~30个碱基长,对重组位点来说则长达200bp)。 (zh)
  • توجد مواقع الربط على جزئ الحمض النووي DNA binding site حيث ترتبط عليها العديد من الجزيئات.تختلف مواقع الربط الحمض النووي عن غيرها من المواقع حيث: 1.انها جزء من تسلسل الحمض النووي «على سبيل المثال الجينوم» 2.انها ترتبط عن طريق روابط الحمض النووي البروتيني. ترتبط مواقع ربط الحمض النووي في كثير من الاحيان مع بروتينات متخصصة المعروفة باسم عوامل النسخ والتي ترتبط بالتنظيم النسخي.ويشار إلى مجموع مواقع ربط الحمض النووي لعامل النسخ ب "cestrome".وتشمل مواقع ربط الحمض النووي اهداف البروتينات الأخرى مثل انزيمات التقييد ومواقع الدمج الخاصة وناقلة الميثيل-دنا. (ar)
  • DNA binding sites are a type of binding site found in DNA where other molecules may bind. DNA binding sites are distinct from other binding sites in that (1) they are part of a DNA sequence (e.g. a genome) and (2) they are bound by DNA-binding proteins. DNA binding sites are often associated with specialized proteins known as transcription factors, and are thus linked to transcriptional regulation. The sum of DNA binding sites of a specific transcription factor is referred to as its cistrome. DNA binding sites also encompasses the targets of other proteins, like restriction enzymes, site-specific recombinases (see site-specific recombination) and methyltransferases. (en)
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