About: De novo gene birth

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De novo gene birth is the process by which new genes evolve from DNA sequences that were ancestrally non-genic. De novo genes represent a subset of novel genes, and may be protein-coding or instead act as RNA genes. The processes that govern de novo gene birth are not well understood, although several models exist that describe possible mechanisms by which de novo gene birth may occur.

Attributes	Values
rdfs:label	De novo gene birth (en) Gène de novo (fr)
rdfs:comment	Un gène de novo est un gène nouveau qui ne provient pas de gènes préexistants mais de l'ADN non codant. Son apparition se produit chez un individu, pas dans l'espèce entière ; il se répand ensuite sous l'effet de la sélection naturelle ou de la dérive génétique, et s'améliore sous la pression sélective. Inconnus jusqu'en 2006, les gènes de novo pourraient constituer quelques dizaines de pour cent des gènes de nombreuses espèces. (fr) De novo gene birth is the process by which new genes evolve from DNA sequences that were ancestrally non-genic. De novo genes represent a subset of novel genes, and may be protein-coding or instead act as RNA genes. The processes that govern de novo gene birth are not well understood, although several models exist that describe possible mechanisms by which de novo gene birth may occur. (en)
foaf:depiction
dcterms:subject	Modification of genetic information Genes
Wikipage page ID	60852153 (xsd:integer)
Wikipage revision ID	1124523673 (xsd:integer)
Link from a Wikipage to another Wikipage	BLAST Primate Protein secondary structure Rodent Methylation Pristionchus Pristionchus pacificus Bombyx mori Brassicaceae Homo sapiens House mouse DNA methylation DNA microarray Intrinsically disordered proteins Mass spectrometry Saccharomyces cerevisiae Pseudogene Gene duplication Genome-wide association study Genomic phylostratigraphy Open reading frame Overlapping gene François Jacob Gadidae Gene Orphan gene Oryza Ant Antifreeze protein Arabidopsis thaliana Bernard Dujon Lepidoptera Horizontal gene transfer Population genetics Saccharomyces paradoxus Susumu Ohno Brown rat Drosophila erecta Drosophila melanogaster Drosophila simulans Drosophila yakuba Fusion gene GC-content HKA test RNA-Seq Synteny Modification of genetic information Histone Leishmania major J. B. S. Haldane Bacteriophage Protamine Arthropod Genes Effective population size DN/dS ratio Sensu stricto Recombination hotspot Sequence homology Long non-coding RNA Simpson's paradox Western blot Evolvability Molecular evolution Non-coding DNA Saccharomyces POLG Ribosome profiling Quantitative PCR dbr:Wikt:de_novo
sameAs	De novo gene birth De novo gene birth De novo gene birth
dbp:wikiPageUsesTemplate	dbt:Reflist dbt:Short_description dbt:Academic_peer_reviewed
thumbnail	wiki-commons:Special:FilePath/De_Novo_Gene_Birth_Figure_1.png?width=300
has abstract	De novo gene birth is the process by which new genes evolve from DNA sequences that were ancestrally non-genic. De novo genes represent a subset of novel genes, and may be protein-coding or instead act as RNA genes. The processes that govern de novo gene birth are not well understood, although several models exist that describe possible mechanisms by which de novo gene birth may occur. Although de novo gene birth may have occurred at any point in an organism's evolutionary history, ancient de novo gene birth events are difficult to detect. Most studies of de novo genes to date have thus focused on young genes, typically taxonomically restricted genes (TRGs) that are present in a single species or lineage, including so-called orphan genes, defined as genes that lack any identifiable homolog. It is important to note, however, that not all orphan genes arise de novo, and instead may emerge through fairly well characterized mechanisms such as gene duplication (including retroposition) or horizontal gene transfer followed by sequence divergence, or by gene fission/fusion. Although de novo gene birth was once viewed as a highly unlikely occurrence, several unequivocal examples have now been described, and some researchers speculate that de novo gene birth could play a major role in evolutionary innovation. (en) Un gène de novo est un gène nouveau qui ne provient pas de gènes préexistants mais de l'ADN non codant. Son apparition se produit chez un individu, pas dans l'espèce entière ; il se répand ensuite sous l'effet de la sélection naturelle ou de la dérive génétique, et s'améliore sous la pression sélective. Inconnus jusqu'en 2006, les gènes de novo pourraient constituer quelques dizaines de pour cent des gènes de nombreuses espèces. (fr)
prov:wasDerivedFrom	wikipedia-en:De_novo_gene_birth?oldid=1124523673&ns=0
page length (characters) of wiki page	125679 (xsd:nonNegativeInteger)
foaf:isPrimaryTopicOf	wikipedia-en:De_novo_gene_birth
is rdfs:seeAlso of	Genome evolution Orphan gene
is Link from a Wikipage to another Wikipage of	De novo Intergenic region Intrinsically disordered proteins Gene duplication Genome evolution

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