Edmund Keene (1714 – 6 July 1781) was an English churchman and academic, who was Master of Peterhouse, Cambridge and later served first as Bishop of Chester, then Bishop of Ely. Younger brother of the diplomat Benjamin Keene, the family were close friends of Sir Robert Walpole, British Prime Minister from 1721 to 1742. This connection helped him secure a series of lucrative positions in his early career but it was his relationship with Walpole's successor Thomas Pelham-Holles, 1st Duke of Newcastle that proved most beneficial.